第二代雜化顆粒化學(xué)

––TetraethoxysilaneEtOEtOCH2CH2 SiOSiOEt4 +EtOSi2OSiOEthyleneEthyleneBridgedHybridOHOHOHOHOHHCCHOHOH OOO OOOOO SiSiSiSiSiSiSiSi OOOOO2SiOSiSiSiSiSiSiSi H2COOOO OOOOOO1.71.7–– –––XTerraXTerra?MS0%InitialACQUITYACQUITYUPLC**NUSPP=4428NUSPACN/H2O梯度,1.8反壓增高10.000 Efficiency––ACQUITYACQUITY亞乙基橋雜化顆130?,200?,4567=T39<?Eab#c(de;M)+ lM'N '),-.BEHOPQRSTCyano9E]PGHQ`mpH nsUPLCUPLC?BEH130?BEH–––130?BEH >,@ABCDBEHKLM130?BEH130?BEHShield–130?BEH! MNI–#$130?BEHC6(Hexyl)1234567:300?BEHC18三鍵鍵合300?BEHC4<VWX_CUPLCUPLC?HSSUPLCUPLC?CSHZorbax?SBC18ACQUITYUPLCHSSXTerra?XTerra?ACQUITYUPLCPhenylACQUITYUPLC LunaYMCJ'sphere?ACQUITYUPLCHSSYMCJ'sphere?Resolve?ACQUITYUPLCACQUITYUPLCHSSC18ACQUITYUPLCWatersSpherisorb?S5(ln[] ACQUITYUPLC2.1x50mm,1.7μm2.1x50mm,1.8μmMobilePhaseA:0.1%HCOOHinHOMobilePhaseB:0.1%HCOOHinACNFlowRate:1.0mL/min TimeInjectionVolume:1SampleConc:0.01-0.02Temperature:35CDetection:UV@240nmInstrument:ACQUITYUPLCPDA2-Salicylic2-526UPLCUPLC?VanGuard:: 15000 ?_`??- ?? 115243ACQUITYBEH2.1x50mm1.7USPResolution:15243CORTECSUPLC2.1x50mm1.6USPResolution:-7.CompetitorFully-porousCat0.52.1x50mm1.8mRuntime:6minP=31peaksperminuteCORTECSUPLCC+at1.02.1x50mm1.6mRuntime:3minP=65peaksperminuteNote:thegradientisscaledtoaccountforthechangeinflowComparativeseparationsmaynotberepresentativeinall2.1x2.1x100mm1.7mRuntime:12minP=21peaksperminute2.1x50mm1.6mRuntime:6minP=40peaksperminuteNote:thegradientisscaledtoaccountforthechangeincolumnComparativeseparationsmaynotberepresentativeinallZT< BEH無以倫比的pH穩(wěn)定性流動(dòng)相與溫度通用性

HSS可無縫轉(zhuǎn)換至

CSH可無縫轉(zhuǎn)換至

更高的柱效與分離?9?f?;?