N-5-Aminopentyl-acetamide-Monoacetylcadaverine-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEN-(5-Aminopentyl)acetamideCat. No.: HY-101403CAS No.: 32343-73-0Synonyms: Monoacetylcadaverine分式: CHNO分量: 144.21作靶點(diǎn): Endogenous Metabolite作通路: Metabolic Enzyme/Protease儲(chǔ)存式: Pure form -20C 3 years4C 2 yearsIn solvent -80C 6 month

2、s-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 30 mg/mL (208.03 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 6.9343 mL 34.6717 mL 69.3433 mL5 mM 1.3869 mL 6.9343 mL 13.8687 mL10 mM 0.6934 mL 3.4672 mL 6.9343 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。BIOLOGICAL ACT

3、IVITY物活性 N-(5-Aminopentyl)acetamide多胺胺的?；问?。IC50 & Target Human Endogenous Metabolite體外研究Polyamine is a small organic polycation composed of a hydrocarbon backbone with multiple amino groups1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEwhich ubiquitously exists in all living organisms from bacter

4、ia to higher animals. The critical step of polyaminebiosynthesis generally includes the amino acid-decarboxylating reaction to produce the primary diamines,such as cadaverine from lysine. Synthesized polyamines are implicated in a wide variety of cytoplasmicreactions such as DNA replication and prot

5、ein synthesis, and are essential for proper growth and proliferationof the organisms 1. Cadaverine is a linear molecule that terminate at both ends with an amine functionalgroup. These functional groups confer to the molecules multiple positive charges at physiological pH.Cadaverine is produced thro

6、ugh the action of basic amino acid decarboxylases and is found associated withthe outer membrane 2.REFERENCES1. Kojima S, et al. Molecular basis for the maintenance of envelope integrity in Selenomonas ruminantium:cadaverine biosynthesis andcovalent modification into the peptidoglycan play a major role. J Nutr Sci Vitaminol (Tokyo). 2012;58(3):153-60.2. Dela Vega AL, et al. Polyamines decrease Escherichia coli outer membrane permeability.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.