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Unit1
1、Somefactorsthatmayleadtothecomplaint:
·Neuronoverload
·Patients*highexpectations
·Mistrustandmisunderstandingbetweenthepatientandthedoctor
2、Mrs.Osorio’cosndition:
·A56-year-oldwoman
·Somewhatoverweight
·Reasonablywell-controlleddiabetesandhypertension
·Cholesterolonthehighsidewithoutanymedicationsforit
·Notenoughexercisessheshouldtake
·HerbonesalittlethinonherlastDEXAscan
3、Goodthings:
·Bloodtestsdone
·Glucosealittlebetter
·HerbloodpressurealittlebetterbutnotsogreatBadthings:
·Cholesterolnotsogreat
·Herweightalittleup
·HerbonesalittlethinonherlastDEXAscan4
4、Thesituation:
·Theauthorwasinamoderatestateofpanic:jugglingsomanythoughtsabout
Mrs.Osorio’sconditionsandtryingtoresolvethemallbeforetheclockrandown.
·Mrs.Osoriomadeatrivialrequest,notsoimportantascomparedtoher
conditions.
·Mrs.Osorioseemedtocareonlyabouther“innocentan—dcompletelyjustified
—request”:theformsignedbyherdoctor.
·Thedoctortriedtooratleastpretendedtopayattentiontothepatientwhile
1
completingdocumentation.
5Similarities:
Incomputermultitasking,amicroprocessoractuallyperformsonlyonetaskata
time.Likemicroprocessors,wehumanbeingscarftactuallyconcentrateontwo
thoughtsatthesameexacttime.Multitaskingisjustanillusionbothincomputers
andhumanbeings.
Differences:
Theconceptofmultitaskingoriginatedincomputerscience.
Atbest,humanbeingscanjuggleonlyahandfulofthoughtsinamultitasking
manner,butcomputerscandomuchbetter.
Themorethoughtshumanbeingsjuggle,thelesshumanbeingsareableto
attunefullytoanygiventhought,butcomputerscandomuchbetter.
6
7medicalissuestoconsider
5separatethoughts,atleast,foreachissue
7x5=35thoughts
10patientsthatafternoon
35x10=350thoughts
5residentsundertheauthorssupervision
4patientsseenbyeachresident
10thoughts,atleast,generatedfromeachpatient
5x4x10=anther200thoughts
350+200=550thoughtstobehandledintotal
Ifthedoctordoesagoodjobjuggling98%ofthetime,thatstillleavesabout10
thoughtsthatmightgetlostintheprocess.
7Possiblesolutions:
Computer-generatedreminders
2
Casemanagers
Ancillaryservices
Thesimplestsolution:time
Unit2
1Theauthorimplies:
Peoplesinadequateconsciousnessabouttheconsequenceofneglectingthere
emerginginfectiousdiseases
-
Unjustifiabilityofpeoplescomplacencyaboutthepreventionandcontrolofthe
infectiousdiseases
Unfinishedwaragainstinfectiousdiseases
2Victorydeclarations:
SurgeonGeneralWilliamStewart'shyperbolicstatementofclosing
infectiousdisease.
thebookon
Astringofimpressivevictoriesincurredbyantibioticsandvaccines
Thethoughtthatthewaragainstinfectiousdiseaseswasalmostover
Whatfollowedeversince:
AppearanceofnewdiseasessuchasAIDSandEbola
Comebackoftheoldafflictions:
DiphtheriaintheformerSovietUnion
TBinurbancenterslikeNewYorkCity
RisingGroupAstreptococcalconditionslikescarletfever
Thefearofapowerfulnewflustrainsweepingtheworld
3Elaborateonthejoinedbattle:
3
WHOestablishedanewdivisiondevotedtoworldwidesurveillanceandcontrol
ofemergingdiseaseinOctober1995.
CDClaunchedapreventionstrategyin1994.
Congressraisedfundfrom$6.7millionin1995to$26millionin1997.
4Thebordersaremeaninglesstopathogenicmicrobes,whichcantravelfrom
onecountrytoanotherremotecountryinaveryshorttime.
5TB:
PrisonsandhomelesssheltersasidealplacesforTBspread
Emergingofdrug-resistantstrainorevenmulti-drug-resistantstrain
ArideontheHIVw^onbyattackingtheimmunocompromised
GroupAstrep:
Achangeinvirulence
Mutationintheexteriorofthebacterium
Flu:
Constantchangesinitscoat(surfaceantigens)andresultantchangesinitslevel
ofvirulence
6Examples:
ExperimentinEnglandisseeingthewaningimmunitybecauseofnovaccination.
Duetopoorvaccinationefforts,thediphtheriasituationintheformerSoviet
Unionisserious.
'
ThevaccinationratesaredroppinginsomeAmericancities,anditwillleadto
morediphtheriaandwhoopingcough.
7Thefourareasoffocus:
4
Theneedforsurveillance
Updatedsciencecapableofdealingwithdiscoveriesinthefield
Appropriatepreventionandcontrol
Strongpublichealthinfrastructure
8TheinfectiousdiseasessuchasTB,flu,diphtheriaandscarletfeverwillnever
reallygoaway,andthewaragainstthemwillneverend.
Unit3
1Terry'slifebefore
ShelovedpracticingTaeKwonDo
Shelovedthesurgeofadrenalinethatcamewiththecontrolledcombatof
tournaments.
Shecompetednationally,evenwonbronzemedalinthetrialsforthePan
AmericanGames.
Sheattendedmedicalschool,practicedasaninternalmedicineresident,and
becameanacademicgeneralinternist.
Shegotmarriedandgotasonandadaughter.
2ThesymptomsofMSandautoimmunedisease:
Lossofstaminaandstrength
Problemswithbalance
Boutsofhorrificfacialpain
Dipsinvisualacuity
5
3Terrydidthefollowingbeforesheself-experimented:
Shestartedinjections.
Sheadoptedmanypharmacotherapies.
Shebeganherownstudyofliterature:
ShereadarticlesonwebsitessuchasPubMed.
ShesearchedforarticlestestingnewMSdrugsinanimalmodels.
Sheturnedtoarticlesconcerningneurodegenerationofalltypes
Parkinson'sdisease,Huntington'sdisease,andLouGehrig'sdisease.
dementia
Sherelearnedbasicsciencessuchascellularphysiology,biochemistry,and
neurophysiology.
4ApproachesTerrymainlyused:
Self-experimentationwithvariousnutrientstoslowneurodegenerationbasedon
literaturereportsonanimalmodels
Self-experimentationwithneuromuscularelectricalstimulationwhichisnotan
approvedtreatmentforMS
Onlinesearchtoidentifythesourcesofmicronutrientsandhavinganewdiet
Reductionoffoodallergiesandtoxicload
5Casesmentionedinthetext:
Increasedmercurystoresinthebrainsofpeoplewithdentalfillings
HighlevelsoftheherbicideatrazineinprivatewellsinIowa
Thestrongassociationbetweenpesticideexposureandneurodegeneration
Theassociationofsinglenucleotidepolymorphismsinvolvingmetabolismof
sulfurand/orBvitamins
Inefficientclearingoftoxins
6
6With70%to90%oftheriskfordiabetes,heartdisease,cancer,and
autoimmunitybeingduetoenvironmentalfactorsotherthanthegenes,wecan
takemanyhealthproblemsandthehealthcarecrisisunderourcontrol,for
example,optimizingournutritionandreducingourtoxicload.
Unit4
1Twoconcepts:
Complementarymedicinereferstotheuseofconventionaltherapiestogetherwith
alternativetreatmentssuchasusingacupunctureinadditiontousualcaretohelp
lessenpain.ComplementaryandalternativemedicineisshortenedasCAM.
Alternativemedicinereferstohealingtreatmentsthatarenotpartofconventional
therapieslikeacupuncture,massagetherapy,orherbalmedicine.Theyare
calledsobecausepeopleusedtoconsiderpracticesliketheseoutsidethe
mainstream.
2
TCMdoesnotrequireadvanced,complicated,andinmostcases,expensive
facilities.
TCMemploysneedles,cups,coins,tomentionbutafew.
MostproceduresandoperationsofTCMarenoninvasive.
Thesubstancesusedasmedicinearerawherbsorabstractsfromthem,and
theyareindeedallnatural,fromnature.
TCMhasbeenpracticedaslongastheChinesehistory,sotheefficiencyis
provenandensured.
7
Ongoingresearcharoundtheworldonacupuncture,herbs,massageandTaiChi
haveshedlightonsomeofthetheoriesandpracticesofTCM
3Itmaybeusedasanadjuncttreatment,analternative,orpartofa
comprehensivemanagementprogramforanumberofconditions:post-operative
andchemotherapyinducednauseaandvomiting,post-operativedentalpain,
addiction,strokerehabilitation,headache,menstrualcramps,tenniselbow,
fibromyalgia,myofascialpain,osteoarthritis,lowbackpain,carpaltunnel
syndrome,andasthma.
4Awell-justifiedNO:
Moreintenseresearchtouncoveradditionalareasfortheuseofacupuncture
Higheradoptionofacupunctureasacommontherapeuticmodalitynotonlyin
treatmentbutalsoinpreventionofdiseaseandpromotionofwellness
Explorationandperfectionofinnovativemethodsofacupuncturepoint
stimulationwithtechnologicaladvancement
Improvedunderstandingofneuroscienceandotheraspectsofhuman
physiologyandfunctionbybasicresearchonacupuncture
Greaterinterestbystakeholders
Anincreasingnumberofphysicianacupuncturists
5
Appropriateusesofherbsdependonproperguidance:
ProperTCMdiagnosisofthezhengofthepatient
Correctselectionofthecorrespondingtherapeuticstrategiesandprinciples
thatguidethechoiceofherbsandherbalformulas
Digressionfromeitheroftheaboveguidencewillleadtomisusesofherbs,and
willresultincomplicationsinpatient
8
6
Randomizedcontrolledtrials
Advantages:
Eliminationofthepotentialbiasintheallocationofparticipantstothe
interventiongrouporcontrolgroup
Tendencytoproducecomparablegroups
Guaranteedvalidityofstatisticaltestsofsignificance
Limitations:
Difficultyingeneralizingtheresultsobtainedfromtheselectedsamplingtothe
populationasawhole
Apoorchoiceforresearchwheretemporalfactorsarean
issue
Extremelyheavyresources,requiringverylargesample
groups
Quasi-experiments
Advantages:
Controlgroupcomparisonspossible
Reducedthreatstoexternalvalidityasnaturalenvironmentsdonot
sufferthesameproblemsofartificialityascomparedtoawell-controlled
laboratorysetting.
Generalizationsofthefindingstobemadeaboutpopulationsince
quasiexperimentsarenaturalexperiments
Limitations
Potentialfornon-equivalentgroupsasquasi-experimentaldesignsdo
notuserandomsamplinginconstructingexperimentalandcontrol
9
groups.
Potentialforlowinternalvalidityasaresultofnotusingrandomsampling
methodstoconstructtheexperimentalandcontrolgroups
Cohortstudies
Advantages:
Clearindicationofthetemporalsequencebetweenexposureand
outcome
Particularuseforevaluatingtheeffectsofrareorunusualexposure
Abilitytoexaminemultipleoutcomesofasingleriskfactor
Limitations:
Larger,longer,andmoreexpensive
Pronetocertaintypesofbias
Notpracticalforrareoutcomes
Case-controlstudies
Advantages:
Theonlyfeasiblemethodinthecaseofrarediseasesandthosewithlong
periodsbetweenexposureandoutcome
Timeandcosteffectivewithrelativelyfewersubjectsascomparedtoother
observationalmethods
Limitations
Unabletoprovidethesamelevelofevidenceasrandomizedcontrolledtrials
asitisobservationalinnature
Difficulttoestablishthetimelineofexposuretodiseaseoutcome
N=1trials
Advantages
Easytomanage
Inexpensive
10
Limitations
Findingsdifficulttobegeneralizedtothewholepopulation
Weakestevidenceduetothenumberofthesubject
7
Synthesisofevidenceiscompletelydependenton:
Thecompletenessoftheliteraturesearch(unavailableforforeignstudies)
Theaccuracyofevaluation
Therearesituationsinwhichnoanswercanbefoundforthequestionsof
interestinRCTsanddatabaseanalyses.
There'stherequirementofusinglessstringentinformationratherthanhard
data
8
Assessmentoftheintrinsicvalueoftraditionalmedicineinsociety
Researchandeducation
Political,economic,andsocialfactors
11
Unit5
1
Dis-easereferstotheimbalancearisingfrom
Continuousstress
Pain
Hardships
Diseaseisahealthcrisisascribabletovariousdis-eases.
Promptingeliminationofdis-easescanalleviatesomediseases.
2
Wellnessisastateinvolvingeveryaspectofourbeing:body,mindandspirit.
Manifestationsofahealthyperson:
Energyandvitality
Acertainzipingait
Awarmfeelingofpeaceofheartseenthroughbehavior
3
Constantmessages,positiveandnegativearesenttoourmindaboutthe
healthofourbody.
Physicalsymptomsaresuppressedbypeoplewhogothroughlifeonautomatic
pilot.
Beingwellequalstobeingdisease-orillness-freeinthemindsofthem.
Theyconfusedwellnesswithanabsenceofsymptoms.
4
People'smindsareinfectedbyspin:
Half-truth
Fearfulfictions
Blatantdeceit:someasaformofself-deceit
Spinisaresultofunconsciousliving.
12
Thekindoffalsenessispandemic.
5
Ourbodyintelligenceissuppressedordormantfromalackofuse.
Therearetremendousamountofstressonadailybasis.
Ourbodiesareeasilyignoredforyearsbecauseofalackofrecreationtime.
Limiting,self-defeatingandevenself-destructivebehaviorsundermineour
wellbeingandkeepthemfromachievingourfullpotential.
6
Wegrowmorereluctanttotakerisks.
Welosetheabilitytofeelandacknowledgeourdeepestfeelingsandthe
couragetospeakourtruth.
Wecontinuetodenyandrepressourfeelingstoprotectourselves.
Fear,denialanddisconnectionfromourbodiesandfeelingsbecomean
unconscious,self-protectivehabit,akindofdefaultresponsetolife.
7
Amulti-facetedprocess:
Lookingforrootsofandresolutionsfortheissuesindifferentdimensions
Buildingourwellnesstoolboxslowly
Picturingourwholestateofbeing
Attentiontothelittlestuff:
Examiningourliveshonestlyandsettingclearintentionstochange
Strivingtomaintainabalanceofourmind,bodyandspirit
Takingsmallstepsinthewaytoperceiveandresolveconflict
8
Trytoawakenandevolveinordertolivemoreconsciously.
Getintouchwithourgenuinefeelingsandemotions.
Cometotermswiththetoxicemotions
13
Unit6
1Inthepast,mostpeoplediedathome.Butnow,moreandmorepeoplearecared
inhospitalsandnursinghomesattheirendoflife,whichofcoursebringsanew
setofquestionstoconsider.
2
Sixty-fouryearsoldwithahistoryofcongestiveheartfailure
Decidingtodoeverythingmedicallypossibletoextendhislife
Availabilityofaround-the-clockmedicalservicesandafullrangeoftreatment
choices,tests,andothermedicalcare
Relaxedvisitinghours,andpersonalitemsfromhome
3Availabilityofaround-the-clockmedicalresources,includingdoctors,nurses,and
facility.
4
Takingonajobwhichisbigphysically,emotionally,andfinancially
Hiringahomenurseforadditionalhelp
Arrangingforservices(suchasvisitingnurses)andspecialequipment(likea
hospitalbedorbedsidecommode)
5
Healthinsurance
Planningbyaprofessional,suchasahospitaldischargeplaimerorasocial
worker
Helpfromlocalgovernmentalagencies
Doctor'ssupervisionathome
6
Traditionally,itisonlyaboutsymptomcare.
Recently,itisacomprehensiveapproachtoimprovingthequalityoflifefor
peoplewhoarelivingwithpotentiallyfataldiseases.
14
7
Stoppingtreatmentspecificallyaimedatcuringanillnessequalsdiscontinuingall
treatment.
Choosingahospiceisapermanentdecision.
Unit7
1
Adyingpatient
Decisionwhethertowithdrawlife-supportmachinesandmedicationandstart
comfortmeasures
Thefamily'srefusaltomakeanydecisionorwithdrawanytreatments
2
Thedoctorasexclusivedecision-maker
Thepatientasparticipantwithlittlesayinthefinalchoice
3
4
Respectforthepatient,especiallythepatientsautonomy
Patient-centeredcare
Thepatientasdecision-makerbasedontheinformationprovidedbythedoctor
Patientsareforcedtomakedecisionstheyneverwantto.
Patients,atleastalargemajorityofthem,prefertheirdoctorstomakefinal
decisions.
Shiftingresponsibilityofdecision-makingtopatientswillbringaboutmorestress
topatientsandtheirfamilies,especiallywhenthebestoptionforthepatientis
uncertain.
15
5Doctorsareverymuchcautiousaboutcommittingsomekindofethical
transgression.
6
Shoulderingresponsibilitytogetherwiththepatientmaybebetterthanhaving
thepatientmakedecisionsontheirown.
Balancingbetweenpaternalismandrespectforpatientsautonomyconstitutesa
largepartofmedicalpractice.
Unit8
1
Research:
Anactivitytotesthypothesis,topermitconclusionstobedrawn,andtherebyto
developorcontributetogeneralizableknowledge
Practice:
Interventionssolelytoenhancethewell-beingofanindividualpatientorclien
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