2022年醫(yī)學(xué)專題-肝性腦病英文PPT

HepaticEncephalopathy

（HE）DongXuan第一頁，共二十頁。Parts

DefinitionCausesHypothesisSymptomsandSignsExaminationsTreatment第二頁，共二十頁。severeliverdiseases.metabolicdisordercentralnervoussystemdisorder

mainclinicalsymptoms

disturbanceofconsciousnessbehaviordisordercoma

points第三頁，共二十頁。DefinitionHEisacomplex,potentiallyreversibledisturbanceincentralnervoussystemthatoccursasaconsequenceofsevereliverdiseases.第四頁，共二十頁。CausesMainCirrhosisSeverehepatitisFulminantliverfailureSeverebiliaryinfectionAcutefattyliverofpregnancyperiod70%causedbycirrhosis

第五頁，共二十頁。PrecipitatingfactorsofHE1)GastrointestinalBleeding2)Abuseofsedativesandnarcotic3)Massiveparacentesisandexcessivediuresis4)InfectionsHypovolemia,shock,hypoxiaProteinbreakdownAmmoniaproduction benzodiazepinesandbarbituratesFluidorelectrolyteabnormalitiesandacidbasedisturbancetissuebreakdown第六頁，共二十頁。SeveralmainhypothesesAmmoniaIntoxicationFalseNeurotransmittersAminoAcidimbalanceTheGamma-AminobutyricAcidhypothesis第七頁，共二十頁。Symptoms(prodromalstage)Slightlyalteredmoodorbehaviors(precomastage)

Somnipathyandinappropriatebehaviors(lethargic

stage)Drowsy

andpsychopath(comastage)DeepcomacentralnervoussystemFourstagesofhepaticencephalopathy

第八頁，共二十頁。第九頁，共二十頁。FlappingtremorPatientB.Doctorandpatient第十頁，共二十頁。ClassificationLevelMentalStatusFlappingtremorⅠSlightlyWeakpositive

ⅡSomnipathyandPositiveinappropriateⅢDrowsyandPositivepsychopathⅣDeepcomaNegative

第十一頁，共二十頁。Examinations1)Bloodammoniachronic()acute()2)EEGslowsmallvalue3)PsychometrictestAdvantages:simple,noequipmentDisadvantage:influencedbyageandeducation第十二頁，共二十頁。Numberconnectiontest第十三頁，共二十頁。Graphicsconnectiontest第十四頁，共二十頁。Imagingexamination(CTorMRI)AcuteHE:CerebraledemaChronicHE:Encephalatrophy

第十五頁，共二十頁。Criticalfricker-fusionfrequencyThroughtestingtheretinalglialcelllesiontojudgethebrainastrocyteshaveswellingAdvantages:sensitive,simpleandreliable第十六頁，共二十頁。TreatmentPrinciples1）Eliminatingorcorrectingprecipitatingfactors2）Reducingplasmaammoniaandothertoxin3）Correctingplasmaaminoacidimbalanceandsupplyingnormalneurotransmitters第十七頁，共二十頁。4)Improvinghepatocytefunctions5)Livertransplantation第十八頁，共二十頁。Thankyou第十九頁，共二十頁。內(nèi)容(nèiróng)總結(jié)HepaticEncephalopathy

（HE）。1)