Dienogest-STS-557-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEDienogestCat. No.: HY-B0084CAS No.: 65928-58-7Synonyms: STS 557分式: CHNO分量: 311.42作靶點: Progesterone Receptor; Autophagy作通路: Others; Autophagy儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 2

2、5 mg/mL (80.28 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.2111 mL 16.0555 mL 32.1110 mL5 mM 0.6422 mL 3.2111 mL 6.4222 mL10 mM 0.3211 mL 1.6055 mL 3.2111 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內實驗請根據(jù)您的實驗動物和給藥式選擇適當?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次添加助溶?為保證實驗結果的可靠性，體內實驗的作液，建

3、議您現(xiàn)現(xiàn)配，當天使；澄清的儲備液可以根據(jù)儲存條件，適當保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (8.03 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (8.03 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oil1/2 Maste

4、r of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.5 mg/mL (8.03 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Dienogest(STS-557)孕酮受體激動劑，有服的宮內膜活性，可作于宮內膜異位。REFERENCES1. Oettel M, et al. Effect of ethinyl estradiol-dienogest combination on serum androgen concentrations. Zentralbl Gynakol.1997;119(12):5

5、97-606.2. Meena R, et al. Extended intervention time and evaluation of sperm suppression by dienogest plus testosterone undecanoate in malerat. Contraception. 2012 Jan;85(1):113-21.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58955