20α-Dihydroprogesterone-20-OH-P-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemE20α-DihydroprogesteroneCat.No.:HY-113062CASNo.:145-14-2Synonyms:20-OH-P分?式:C??H??O?分?量:316.48作?靶點(diǎn):EndogenousMetabolite;CytochromeP450作?通路:MetabolicEnzyme/Protease儲(chǔ)存?式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性數(shù)據(jù)體外實(shí)驗(yàn)DMSO:50mg/mL(157.99mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM3.1598mL15.7988mL31.5976mL5mM0.6320mL3.1598mL6.3195mL10mM0.3160mL1.5799mL3.1598mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；?旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲(chǔ)備液的保存?式和期限：-80°C,6months;-20°C,1month。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?。BIOLOGICALACTIVITY?物活性20α-DihydroprogesteroneProgesterone(HY-N0437)的代謝物。20α-Dihydroprogesterone抑制乳腺組織中的細(xì)胞增殖和遷移。20α-Dihydroprogesterone在細(xì)胞MCF-7aro中抑制芳?化酶(aromatase)，IC50約為5μM。1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemEIC50&TargetHumanEndogenousMetaboliteREFERENCES[1].PasqualiniJR,etal.,Theanti-aromataseeffectofprogesteroneandofitsnaturalmetabolites20alpha-and5alpha-dihydroprogesteroneintheMCF-7arobreastcancercellline.AnticancerRes.2008Jul-Aug;28(4B):2129-33.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:021-53700