Ferulic-acid-4-O-sulfate-Ferulic-acid-4-sulfate-DataSheet-生命科學試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEFerulicacid4-O-sulfateCat.No.:HY-147323CASNo.:86321-29-1Synonyms:Ferulicacid4-sulfate分?式:C??H??O?S分?量:274.25作?靶點:DrugMetabolite作?通路:MetabolicEnzyme/Protease儲存?式:Powder-20°C3yearsInsolvent-80°C6months-20°C1month溶解性數(shù)據(jù)體外實驗DMSO:10mg/mL(36.46mM;ultrasonicandwarmingandheatto60°C)MassSolvent1mg5mg10mgConcentration制備儲備液1mM3.6463mL18.2315mL36.4631mL5mM0.7293mL3.6463mL7.2926mL10mM0.3646mL1.8232mL3.6463mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲備液；?旦配成溶液，請分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲備液的保存?式和期限：-80°C,6months;-20°C,1month。-80°C儲存時，請在6個?內(nèi)使?，-20°C儲存時，請在1個?內(nèi)使?。BIOLOGICALACTIVITY?物活性Ferulicacid4-O-sulfate(Ferulicacid4-sulfate)Ferulicacid(HY-N0060)的代謝物。Ferulicacid4-O-sulfate可以放松??的動脈，降低?壓。體外研究Ferulicacid4-O-sulfate(0.1-30μM)causessignificantconcentration-dependentrelaxationsinmouseaorta,femoralandsaphenousarteries[1].1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemE體內(nèi)研究Ferulicacid4-O-sulfate(16.13and161.3μg/kg;i.v.;once)relaxesarteriesandlowersbloodpressureinmice[1].AnimalModel:MaleSwissmice[1]Dosage:16.13and161.3μg/kgAdministration:Intravenousinjection,onceResult:Significantlydecreasedthemeanarterialpressure(MAP)immediatelyafterintravenousinjection.REFERENCES[1].VanRymenantE,etal.Ferulicacid-4-O-sulfateratherthanferulicacidrelaxesarteriesandlowersbloodpressureinmice.JNutrBiochem.2017Jun;44:44-51.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-589559