代謝綜合征MS因子分析

北京地區(qū)中老年人群代謝綜合征(MS)的因子分析潘麗麗陸菊明單彬張高魁盧艷慧王淑玉鄭華李春霖劉力生鄭潤(rùn)平田慧潘長(zhǎng)玉

1背景：代謝綜合征（MS）存在較多爭(zhēng)議（是否存在，定義，病理生理機(jī)制等）目的：用因子分析的方法分析MS各組分在不同人群（NGT,IGT,DM和CHD）的聚集情況

2因子分析的基本原理及適用研究范圍·1904年ChalesSpearman心理學(xué)領(lǐng)域·體育、教育、心理及經(jīng)濟(jì)等領(lǐng)域·近年在代謝綜合征（MS）領(lǐng)域也有應(yīng)用·將多個(gè)實(shí)測(cè)變量轉(zhuǎn)換成少數(shù)幾“因子”3因子分析應(yīng)用舉例100名學(xué)生各科考試成績(jī)?nèi)缦拢?/p>

4因子分析應(yīng)用舉例5?對(duì)象?方法?結(jié)果?討論

6研究對(duì)象①糖尿病病史的患者②TG>10mmol/L③數(shù)據(jù)有缺失CHD組NGT組IGT組新診斷DM組去除1090人入選對(duì)象1254人平均年齡60.49歲男570人，女684人2004年6月至8月北京石景山地區(qū)≥40歲（平均年齡61歲）流行病學(xué)調(diào)查人群，共計(jì)2344人無(wú)DM病史者行75gOGTT測(cè)量FBG、2hBGFINS、2hINS、TG、HDL、WC、BMI7研究對(duì)象特點(diǎn)8?對(duì)象?方法?結(jié)果?討論

9研究方法SAS軟件EFA10?對(duì)象?方法?結(jié)果?討論

11NGT組變量因子1因子2因子3因子4FINS0.47463＊0.50406＊-0.03534-0.33922PINS0.061570.81385＊0.02423-0.25946BMI0.87355＊0.062320.13458-0.17114WC0.87462＊0.082050.22071-0.16651SBP0.195650.140930.87211＊-0.03310DBP0.095600.037650.88247＊-0.16616TG0.131680.212390.16357-0.69793＊HDL-0.26611-0.01808-0.081270.69679＊FBG0.364780.40208＊0.072660.42109＊PBG0.034620.77241＊0.158710.07128方差貢獻(xiàn)率0.32950.13430.12060.1030累計(jì)方差0.32950.46380.58440.687412研究結(jié)果SBPDBPBMI、WC

PINSFBGPBGFINSTGHDL4123NGT組13IGT組變量因子1因子2因子3FINS0.61468＊-0.199010.67766＊PINS0.30795-0.189760.70573＊BMI0.72796＊0.003520.50434＊WC0.76850＊-0.011850.44926＊SBP0.065600.94944＊-0.09848DBP0.041050.95242＊-0.05673TG0.76565＊-0.14737-0.00467HDL-0.94916＊-0.16047-0.10582FBG0.13982-0.65519＊-0.13143PBG0.01195-0.37847-0.71218＊方差貢獻(xiàn)率0.40670.24920.1014累積方差0.40670.65590.757214研究結(jié)果IGT組TGHDLFINSBMIWC

PINSPBGFBGSBPDBP12315新診斷DM組變量因子1因子2因子3因子4FINS-0.003350.14159-0.113970.86475＊PINS-0.50761＊-0.086150.003920.62025＊BMI-0.002750.74897＊0.095900.32732WC0.089850.76849＊0.128670.18351SBP0.06551-0.136590.93111＊0.08432DBP-0.127460.215080.75733＊-0.29704TG-0.213800.66815＊-0.16039-0.30557HDL-0.31116-0.51533＊0.077810.03122FBG0.92229＊0.11557-0.03902-0.05787PBG0.93796＊-0.087370.02370-0.01327方差貢獻(xiàn)率0.26820.20330.14720.1036累積方差0.26820.47150.61860.722216研究結(jié)果新診斷DM組FBGPBGPINSFINS

BMI、WCTG、HDLSBP、DBP123417CHD組變量因子1因子2因子3因子4FINS0.75411＊0.35167-0.00353-0.11093PINS0.74685＊0.03896-0.019390.15823BMI0.79305＊-0.042030.08846-0.23972WC0.75372＊-0.166070.03146-0.39796SBP0.066880.096850.89470＊0.04950DBP-0.01053-0.018440.91698＊-0.00852TG0.306520.236840.02281-0.67834HDL-0.009170.003230.062110.88406＊FBG-0.058720.93574＊0.03994-0.16222PBG0.132090.93079＊0.045970.00688方差貢獻(xiàn)率0.29450.18660.16320.1144累計(jì)方差0.29450.48110.64430.758818研究結(jié)果CHD組FINSPINSBMIWCFBGPBGSBPDBPHDLTG123419?對(duì)象?方法?結(jié)果?討論

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