Nandrolone-phenylpropionate-DataSheet-生命科學(xué)試劑-MedChemExpress

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemENandrolonephenylpropionateCat.No.:HY-101767CASNo.:62-90-8分?式:C??H??O?分?量:406.56作?靶點(diǎn):AndrogenReceptor作?通路:Others儲(chǔ)存?式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性數(shù)據(jù)體外實(shí)驗(yàn)DMSO:100mg/mL(245.97mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM2.4597mL12.2983mL24.5966mL5mM0.4919mL2.4597mL4.9193mL10mM0.2460mL1.2298mL2.4597mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；?旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲(chǔ)備液的保存?式和期限：-80°C,6months;-20°C,1month。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?。體內(nèi)實(shí)驗(yàn)請(qǐng)根據(jù)您的實(shí)驗(yàn)動(dòng)物和給藥?式選擇適當(dāng)?shù)娜芙?案。以下溶解?案都請(qǐng)先按照InVitro?式配制澄的儲(chǔ)備液，再依次添加助溶劑：(為保證實(shí)驗(yàn)結(jié)果的可靠性，澄的儲(chǔ)備液可以根據(jù)儲(chǔ)存條件，適當(dāng)保存；體內(nèi)實(shí)驗(yàn)的?作液，建議您現(xiàn)?現(xiàn)配，當(dāng)天使?；以下溶劑前顯?的百分?指該溶劑在您配制終溶液中的體積占?；如在配制過程中出現(xiàn)沉淀、析出現(xiàn)象，可以通過加熱和/或超聲的?式助溶)1.請(qǐng)依序添加每種溶劑：10%DMSO>>90%(20%SBE-β-CDinsaline)Solubility:≥2.5mg/mL(6.15mM);Clearsolution1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemE2.請(qǐng)依序添加每種溶劑：10%DMSO>>90%cornoilSolubility:≥2.5mg/mL(6.15mM);ClearsolutionBIOLOGICALACTIVITY?物活性Nandrolonephenylpropionate，19-nortestosterone的衍?物，?種合成代謝類醇，可促進(jìn)蛋?質(zhì)合成。Nandrolonephenylpropionate?于緩解組織分解代謝，可以?于?質(zhì)疏松癥和特納綜合征的研究。體內(nèi)研究Nandrolonephenylpropionate(4.0mg/kg/d;daily;for14days)treatmentsignificantlyincreasestheweightgainofrats.Nandrolonephenylpropionatetreatmentincreasesthemixedmuscleproteinfractionalsyntheticrate(FSR).AndthemusclefreecathepsinDactivityissignificantlyincreasedbyNandrolonephenylpropionatetreatment,indicatingincreasedmuscleproteindegradation,totalcathepsinDactivityisunchanged[1].REFERENCES[1].NWDumelow,etal.Effectofnandrolonephenylpropionateonproteinmetabolisminrats.HormMetabRes.1985Aug;17(8):431.[2].KNoda,etal.Effectsoftheanabolicsteroidnandrolonephenylpropionateoncraniofacialgrowthinrats.JMorphol.1994Apr;220(1):25-33.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-