DNQX-FG-9041-DataSheet-生命科學試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEDNQXCat. No.: HY-15067CAS No.: 2379-57-9Synonyms: FG 9041分式: CHNO分量: 252.14作靶點: iGluR作通路: Membrane Transporter/Ion Channel; Neuronal Signaling儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO :

2、 35 mg/mL (138.81 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.9661 mL 19.8303 mL 39.6605 mL5 mM 0.7932 mL 3.9661 mL 7.9321 mL10 mM 0.3966 mL 1.9830 mL 3.9661 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗 請根據(jù)您的實驗動物和給藥式選擇適當?shù)娜芙獍福渲魄罢埾扰渲瞥吻宓膬湟?，再依?/p>

3、添加助溶劑(為保證實驗結(jié)果的可靠性，體內(nèi)實驗的作液，建議您現(xiàn)現(xiàn)配，當天使；澄清的儲備液可以根據(jù)儲存條件，適當保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (9.92 mM); Clear solution1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemEBIOLOGICAL ACTIVITY物活性 DNQX (FG 9041)個AMPA受體的拮抗劑。IC50 & Target AMPA rec

4、eptor 1.體外研究 DNQX (FG 9041), added 2 h after cell plating, induces a dose-dependent neurotoxicity.REFERENCES1. Watkins JC et al. Structure-activity relationships in the development of excitatory amino acid receptor agonists and competitiveantagonists. Trends Pharmacol Sci. 1990 Jan;11(1):25-33.2. Honor T et al. Quinoxalinediones: potent competitive non-NMDA glutamate receptor antagonists. Science. 1988 Aug 5;241(4866):701-3.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>