化妝品衛(wèi)生規(guī)范(2007版)化妝品組分中限用防腐劑

1、精品文檔表4化妝品組分中限用防腐劑(按INCI名稱英文字母順序排列)序號物質(zhì)名稱化妝品中大允許使用濃 度使用范圍和限制條件標(biāo)簽上必須標(biāo)印的使用條件和注意事項中文名稱英文名稱INCI名稱12-漠-2-硝基丙烷-1,3二醇Bronopol (INN)2-Bromo-2-nitropropane-1,3-diol0.1%避免形成亞硝胺25-漠-5-硝基-1,3-二嗯烷5-Bromo-5-nitro-1,3-dioxane5-Bromo-5-nitro-1,3-dioxane0.1%僅用于淋洗類產(chǎn)品；避 免形成亞硝胺37-乙基二環(huán)嗯建琳5-Ethyl-3,7-dioxa-1-azabicyclo3.3

2、.0octane7-Ethylbicyclooxazolidine0.3%禁用于口腔衛(wèi)生產(chǎn)品和 接觸粘膜的產(chǎn)品4烷基(C12-C22)三甲基鏤漠化物或氯化物(2)Alkyl(C 12-C22) trimethyl ammonium, bromide and chlorideAlkyl(C 12G2) trimonium bromide and chloride0.1%5苯扎氯鏤,苯扎漠鏤, 苯扎糖精鏤Benzalkonium chloride, bromide andsaccharinateBenzalkonium chloride, bromide and saccharinate0.1%(

3、以苯扎氯鏤計)避免接觸眼睛6士索氯鏤Benzethonium chlorideBenzethonium chloride0.1%(1)淋洗類產(chǎn)品(2)口腔衛(wèi)生用品之外的駐留類產(chǎn)品7苯甲酸及其鹽類和酯類(2)Benzoic acid, its salts and estersBenzoic acid, its salts and esters0.5%(以酸計)8苯甲醇Benzyl alcoholBenzyl alcohol1.0%9甲醛葦醇半縮醛BenzylhemiformalBenzylhemiformal0.15%僅用于淋洗類產(chǎn)品10漠氯芬6,6-Dibromo-4,4-dichloro-

4、2,2 -methylene-diphenolBromochlorophen0.1%11氯已定及其二葡萄糖酸 鹽，二醋酸鹽和二鹽酸 鹽Chlorhexidine (INN) and its digluconate,diacetate and dihydrochlorideChlorhexidine and its digluconate, diacetate and dihydrochloride0.3%(以氯己定表示)12氯乙酰胺2-ChloroacetamideChloroacetamide0.3%含氯乙酰胺13三氯叔丁醇Chlorobutanol (INN)Chlorobutanol0.

5、5%禁用于噴霧產(chǎn)品含三氯叔丁醇14正氯酚2-Benzyl-4-chlorophenolChlorophene0.2%15氯二甲酚4-Chloro-3,5-xylenolChloroxylenol0.5%16氯苯甘醴3-(p-chlorophenoxy)-propane-1,2diolChlorphenesin0.3%序號物質(zhì)名稱化妝品中大允許使用濃度使用范圍和限制條件標(biāo)簽上必須標(biāo)印的使用條件和注意事項中文名稱英文名稱INCI名稱17氯咪巴唾1-(4-chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-oneClimbazole0.5%18脫

6、氫醋酸及其鹽類3-Acetyl-6-methylpyran-2,4Dehydroacetic acid0.6%（以酸計）禁用于噴霧產(chǎn)品(3H)-dione and its salts19雙（羥甲基）咪座烷基月尿N-(Hydroxymethyl)- N-(dihydroxy methyl-1,3-dioxo-2,5-imidazolinid yl-4)- N -(hydroxymethyl) ureaDiazolidinyl urea0.5%20二漠己瞇及其鹽類，包 括二漠已瞇羥乙磺酸鹽3,3 -Dibromo- 4,4 -hexamethylene dioxydibenzamidine and

7、 its salts (including isethionate)Dibromohexamidine and itssalts, includingdibromohexamidine isethionate0.1%21二氯苯甲醇2,4-Dichlorobenzyl alcoholDichlorobenzyl alcohol0.15%22二甲基嗯唾烷4,4-Dimethyl-1,3-oxazolidineDimethyl oxazolidine0.1%終產(chǎn)品的pH不得低于623DMDM乙內(nèi)酰月尿1,3-Bis(hydroxymethyl)-5,5-dimethylimidazolidine-2

8、,4-dioneDMDM hydantoin0.6%24甲醛和多聚甲醛（2）Formaldehyde and paraformaldehydeFormaldehyde and paraformaldehyde0.2%（口腔衛(wèi)生產(chǎn)品除外）0.1%（口腔衛(wèi)生產(chǎn)品）（以游離甲醛計）禁用于噴霧產(chǎn)品25甲酸及其鈉鹽Formic acid and its sodium saltFormic acid and its sodium salt0.5%（以酸計）26戊二醛Glutaraldehyde (Pentane-1,5-dial)Glutaral0.1%禁用于噴霧產(chǎn)品含戊二醛（當(dāng)成品中 戊二醛濃度超過0.

9、05% 時）27己瞇定及其鹽，包括己 瞇定二個羥乙基磺酸鹽 和己瞇定對羥基苯甲酸 鹽1,6-Di(4-amidinophenoxy)- n-hexa ne and its salts (including isethionate and p -hydroxybenzoate)Hexamidine and its salts, including hexamidine diisethionate and hexamidine paraben0.1%28?？颂孢錒exetidine (INN)Hexetidine0.1%29咪唾烷基月尿3,3 -Bis(1-hydroxymethyl-2,5-di

10、o xoimidazolidin-4-yl)- 1,1 -methyle nediureaImidazolidinyl urea0.6%30無機(jī)亞硫酸鹽類和亞硫酸氫鹽類Inorganic sulphites andhydrogensulphitesInorganic sulfites and hydrogensulfites0.2%（以游離SO2計）序號物質(zhì)名稱化妝品中大允許使用濃使用范圍和限制條件標(biāo)簽上必須標(biāo)印的中文名稱英文名稱INCI名稱度使用條件和注意事項31碘丙煥醇丁基氨甲酸酯3-Iodo-2-propynylbutylcarbamateIodopropynyl butylcarbam

11、ate0.05%不能用于口腔衛(wèi)生和唇部產(chǎn)品用后存留在皮膚上 的產(chǎn)品，當(dāng)其濃度超 過0.02%時，需注明如下警示語：含碘32烏洛托品Hexamethylenetetramine (INN)Methenamine0.15%33甲基二漠戊二睛1,2-Dibromo-2,4-dicyanobutaneMethyldibromo glutaronitrile0.1%僅用于淋洗類產(chǎn)品34甲基異曝座啾酮2-Methylisothiazol-3(2 H)-oneMethylisothiazolinone0.01%35甲基氯異曝晚琳酮和甲 基異曝座琳酮與氯化鎂 及硝酸鎂的混合物Mixture of5-chlor

12、o-2-methylisothiazol-3(2 H)-one and2-methylisothiazol-3(2 H)-one with magnesium chloride and magnesium nitrateMixture ofmethylchloroisothiazolinone and methylisothiazolinone with magnesium chloride and magnesium nitrate0.0015%（以甲基氯異曝座 啾酮和甲基異曝座啾酮為3: 1的混合物計）36o-傘花燒-5-醇4-Isopropyl- m-cresolo-Cymen-5-ol

13、0.1%37。-苯基苯酚Biphenyl-2-ol and its saltso-Phenylphenol0.2%(以苯酚計)384-羥基苯甲酸及其鹽類和酯類4-Hydroxybenzoic acid and its salts and esters4-Hydroxybenzoic acid and its salts and esters單一酯：0.4%(以酸計)混 合酯：0.8%(以酸計)39p-氯-m甲酚4-Chloro-m-cresolp-Chloro- m-cresol0.2%禁用于接觸粘膜的產(chǎn)品40苯氧乙醇2-PhenoxyethanolPhenoxyethanol1.0%41苯氧

14、異丙醇(2)1-Phenoxypropan-2-olPhenoxyisopropanol1.0%僅用于淋洗類產(chǎn)品42叱羅克酮乙醇胺鹽1-Hydroxy-4-methyl-6(2,4,4-trimethylpentyl)2-pyridon and itsPiroctone olamine(a) 1.0%(b) 0.5%(a)淋洗類產(chǎn)品(b)其它產(chǎn)品monoethanolamine salt43鹽酸聚氨丙基雙服Poly(l-hexamethylenebiguanide)hydrochloridePolyaminopropyl biguanide hydrochloride0.3%44丙酸及其鹽類P

15、ropionic acid and its saltsPropionic acid and its salts2%（以酸計）45聚季鏤鹽-15Methenamine3-chloroallylochloride (INNM)Quaternium-150.2%46水楊酸及其鹽類,2）Salicylic acid and its saltsSalicylic acid and its salts0.5%（以酸計）除香波外，不得用于三 歲以下兒童使用的產(chǎn)品中三歲以下兒童勿用序號物質(zhì)名稱化妝品中大允許使用濃度使用范圍和限制條件標(biāo)簽上必須標(biāo)印的使用條件和注意事項中文名稱英文名稱INCI名稱47苯汞的鹽類，

16、包括硼酸苯汞Phenylmercuric salts (including borate)Salts of phenylmercury, including borate0.007%（以 Hg計），如果 同本規(guī)范中其它汞化合物混合，Hg的大濃度仍為僅用于眼部化妝品和眼部卸妝品含苯汞化合物0.007%48沉積在二氧化鈦上的氯化銀Silver chloride deposited on titanium dioxideSilver chloride deposited on titanium dioxide0.004%(以 AgCl 計)沉積在TiO2上的20%(w/w) AgCl,禁用 于三歲以

17、下兒童使用的 產(chǎn)品、口腔衛(wèi)生產(chǎn)品以 及眼周和唇部產(chǎn)品49羥甲基甘氨酸鈉Sodium hydroxymethylamino acetateSodiumhydroxymethylglycinate0.5%50碘酸鈉Sodium iodateSodium iodate0.1%僅用于淋洗類產(chǎn)品51山梨酸及其鹽類Sorbic acid (hexa-2,4-dienoic acid) and its saltsSorbic acid and its salts0.6%(以酸計)52硫柳汞Thiomersal (INN)Thimerosal0.007%(以 Hg計)，如果 同本規(guī)范中其它汞化合物混合，Hg的

18、大濃度仍為0.007%僅用于眼部化妝品和眼部卸妝品含硫柳汞53三氯卡班Triclocarban (INN)Triclocarban0.2%純度標(biāo)準(zhǔn)：3,3 ,4-和氯偶氮苯少于1mg/kg;3,3 ,4,四氯氧化偶氮苯少于1mg/kg54三氯生Triclosan (INN)Triclosan0.3%55十一烯酸及其鹽類Undec-10-enoic acid and saltsUndecylenic acid and salts0.2%(以酸計)56叱硫翁鋅(2 )Pyrithione zinc (INN)Zinc pyrithione0.5%可用于淋洗類產(chǎn)品，禁用于口腔衛(wèi)生產(chǎn)品(1) a表中所列防腐劑均為加入化妝品中以抑制微生物在該化妝品中生長為目的的物質(zhì)。b化妝品