EPA_目錄USEPA Test Guidelines

EPA OPPTS Harmonized Test Guidelines The Office of Prevention Pesticides and Toxic Substances OPPTS has developed these guidelines through a process of harmonization that blended the testing guidance and requirements that existed in the Office of Pollution Prevention and Toxics OPPT and appeared in title 40 chapter I subchapter R of the Code of Federal Regulations CFR the Office of Pesticide Programs OPP which appeared in publications of the National Technical Information Service NTIS and the guidelines published by the Organization for Economic Cooperation and Development OECD The purpose for harmonizing these guidelines into a single set of OPPTS guidelines is to minimize variations among the testing procedures that must be performed to meet the data requirements of the U S Environmental Protection Agency under the Toxic Substances Control Act TSCA 15 U S C 2601 and the Federal Insecticide Fungicide and Rodenticide Act FIFRA 7 U S C 136 et seq Series The OPPTS harmonized guidelines are organized in the following 10 series 810 Product Performance Test Guidelines 830 Product Properties Test Guidelines 835 Fate Transport and Transformation Test Guidelines 840 Spray Drift Test Guidelines 850 Ecological Effects Test Guidelines 860 Residue Chemistry Test Guidelines 870 Health Effects Test Guidelines 875 Occupational and Residential Exposure Test Guidelines 880 Biochemicals Test Guidelines 885 Microbial Pesticide Test Guidelines Series 810 Product Performance Test Guidelines Finals The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations 1 810 1000 Overview Definitions and General Considerations 20pp 53KB 2 810 3000 General Considerations for Efficacy of Invertebrate Control Agents 5pp 13KB 3 810 3100 Soil Treatments for Imported Fire Ants 4pp 11KB 4 810 3200 Livestock Poultry Fur and Wool Bearing Animal Treatments 8pp 23 KB 5 810 3300 Treatments to Control Pests of Humans and Pets 10pp 26KB 6 810 3400 Mosquito Black Fly and Biting Midge Sand Fly Treatments 5pp 14KB 7 810 3500 Premises Treatments 8pp 23KB 8 810 3600 Structural Treatments 6pp 16KB 9 810 3800 Methods for Efficacy Testing of Termite Baits 22pp 99KB Public Draft 10 810 3700 Insect Repellents For Human Skin and Outdoor Premises PDF 13pp 38 KB Series 830 Product Properties Test Guidelines The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations Public Drafts Guidelines in Public Draft Final Guidelines Final Guidelines Revised Final Guidelines Series 830 Product Performance Test Guidelines Public Drafts The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations 830 1550 Product identity and composition PDF 5pp 16KB 830 1600 Description of materials used to produce the product PDF 4pp 14KB 830 1620 Description of production process PDF 4pp 14KB 830 1650 Description of formulation process PDF 3pp 12KB 830 1670 Discussion of formation of impurities PDF 4pp 15KB 830 1700 Preliminary analysis PDF 5pp 18KB 830 1750 Certified limits PDF 7pp 24KB 830 1800 Enforcement analytical method PDF 5pp 12KB 830 1900 Submittal of samples PDF 3pp 18KB 830 6302 Color PDF 4pp 15KB 830 6303 Physical state PDF 3pp 13KB 830 6304 Odor PDF 3pp 13KB 830 6313 Stability to sunlight normal and elevated PDF 4pp 13KB 830 6314 Oxidizing or reducing action PDF 5pp 19KB 830 6315 Flammability PDF 5pp 20KB 830 6316 Explodability PDF 6pp 21KB 830 6317 Storage stability of product PDF 5pp 15KB 830 6319 Miscibility PDF 5pp 18KB 830 6320 Corrosion characteristics PDF 4pp 16KB 830 6321 Dielectric breakdown voltage PDF 5pp 18KB 830 7000 pH of water solutions or suspensions PDF 3pp 13KB 830 7050 UV Visible absorption PDF 7pp 20KB 830 7100 Viscosity PDF 7pp 31KB 830 7200 Melting point melting range PDF 5pp 20KB 830 7220 Boiling point boiling range PDF 13pp 87KB 830 7300 Density relative density PDF 5pp 22KB 830 7370 Dissociation constant in water PDF 8pp 31KB 830 7520 Particle size fiber length and diameter distribution PDF 13pp 99KB 830 7550 Partition coefficient n octanol H2O shake flask method PDF 8pp 33KB 830 7560 Partition coefficient PDF 20pp 83KB 830 7570 Partition coefficient n octanol H2O estimation by liquid PDF 11pp 37KB 830 7840 Water solubility Column elution method shake flask PDF 14pp 60KB 830 7860 Water solubility generator column method PDF 19pp 72KB 830 7950 Vapor pressure PDF 19pp 76KB Series 830 Product Performance Test Guidelines Finals The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations 830 1000 Background for product properties test guidelines PDF 23pp 66KB 830 1550 Product identity and composition PDF 5pp 12KB 830 1600 Description of materials used to produce the product PDF 4pp 10KB 830 1620 Description of production process PDF 4pp 10KB 830 1650 Description of formulation process PDF 4pp 8KB 830 1670 Discussion of formation of impurities PDF 4pp 11KB 830 1700 Preliminary analysis PDF 5pp 13KB 830 1750 Certified limits PDF 5pp 8KB 830 1800 Enforcement analytical method PDF 3pp 8KB 830 1900 Submittal of samples PDF 3pp 11KB 830 6302 Color PDF 4pp 9KB 830 6303 Physical state PDF 3pp 9KB 830 6304 Odor PDF 3pp 12KB 830 6313 Stability to normal and elevated PDF 4pp 11KB 830 6314 Oxidation reduction chemical incompatability PDF 4pp 13KB 830 6315 Flammability PDF 5pp 13KB 830 6316 Explodability PDF 5pp 13KB 830 6317 Storage stability PDF 4pp 11KB 830 6319 Miscibility PDF 4pp 11KB 830 6320 Corrosion characteristics PDF 3pp 9KB 830 6321 Dielectric breakdown voltage PDF 4pp 11KB 830 7000 pH PDF 3pp 9KB 830 7050 UV Visible absorption PDF 7pp 19KB 830 7100 Viscosity PDF 7pp 23KB 830 7200 Melting point melting range PDF 15pp 4KB 830 7220 Boiling point boiling range PDF 13pp 66KB 830 7300 Density relative density bulk density PDF 5pp 16KB 830 7370 Dissociation constant in water PDF 8pp 23KB 830 7520 Particle size fiber length and diameter distribution PDF 13pp 97KB 830 7550 Partition coefficient n octanol water shake flask method PDF 9pp 25KB 830 7560 Partition coefficient PDF 21pp 81KB 830 7570 Partition coefficient n octanol water estimation by liquid PDF 11pp 35KB 830 7840 Water solubility Column elution method shake flask PDF 14pp 59KB 830 7860 Water solubility generator column method PDF 19pp 71KB 830 7950 Vapor pressure PDF 19pp 75KB Series 830 Product Performance Test Guidelines Revised Final Guidelines The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations Revised March 1998 830 1000 Background for product properties test guidelines PDF 23pp 66KB 830 7200 Melting point melting range PDF 5pp 15KB 830 7300 Density relative density bulk density PDF 5pp 16KB 830 7840 Water solubility column elution method shake flask PDF 14pp 59KB 830 7860 Water solubility generator column method PDF 19pp 66KB Revised June 2002 830 6317 Storage stability PDF 4pp 16KB 830 7300 Density relative density bulk density PDF 5pp 74KB Series 835 Fate Transport and Transformation Test Guidelines Public Drafts The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations 835 1110 Activated sludge sorption isotherm PDF 9pp 32KB 835 1210 Soil thin layer chromatography PDF 8pp 29KB 835 1220 Sediment and soil adsorption desorption isotherm PDF 20pp 74KB 835 2110 Hydrolysis as a function of pH PDF 18pp 83KB 835 2130 Hydrolysis as a function of pH and temperature PDF 16pp 69KB 835 2210 Direct photolysis rate in water by sunlight PDF 37pp 173KB 835 2310 Maximum direct photolysis rate in air from UV visible spectroscopy PDF 21pp 121KB 835 3100 Aerobic aquatic biodegradation PDF 10pp 75KB 835 3110 Ready biodegradability PDF 55pp 203KB 835 3120 Sealed vessel carbon dioxide production test PDF 15pp 43KB 835 3170 Shake flask die away test PDF 11pp 49KB 835 3180 Sediment water microcosm biogradation test PDF 14pp 40KB 835 3200 Zahn Wellens EMPA test PDF 14pp 63KB 835 3210 Modified SCAS test PDF 8pp 28KB 835 3220 Porous pot test PDF 23pp 164KB 835 3300 Soil biodegradation PDF 10pp 51KB 835 3400 Anaerobic biodegradability of organic chemicals PDF 10pp 34KB 835 5045 Modified SCAS test for insoluble and volatile chemicals PDF 7pp 14KB 835 5154 Anaerobic biodegradation in the subsurface PDF 12pp 41KB 835 5270 Indirect photolysis screening test Sunlight photolysis in waters containing dissolved humic substances PDF 24pp 104KB Series 835 Fate Transport and Transformation Test Guidelines Final Guidelines The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations 835 1110 Activated sludge sorption isotherm PDF 9pp 25KB 835 1210 Soil thin layer chromatography PDF 8pp 21KB 835 1220 Sediment and soil adsorption desorption isotherm PDF 20pp 56KB 835 2110 Hydrolysis as a function of pH PDF 18pp 44KB 835 2130 Hydrolysis as a function of pH and temperature PDF 16pp 40KB 835 2210 Direct photolysis rate in water by sunlight PDF 37pp 127KB 835 2310 Maximum direct photolysis rate in air from UV visible spectroscopy PDF 21pp 91KB 835 3100 Aerobic aquatic biodegradation PDF 10pp 53KB 835 3110 Ready biodegradability PDF 55pp 156KB 835 3120 Sealed vessel carbon dioxide production test PDF 14pp 41KB 835 3160 Biodegradability in sea water PDF 33pp 111KB 835 3170 Shake flask die away test PDF 11pp 30KB 835 3180 Sediment water microcosm biogradation test PDF 14pp 38KB 835 3200 Zahn Wellens EMPA test PDF 10pp 46KB PDF 835 3210 Modified SCAS test PDF 8pp 21KB 835 3220 Porous pot test PDF 24pp 129KB 835 3300 Soil biodegradation PDF 10pp 38KB 835 3400 Anaerobic biodegradability of organic chemicals PDF 10pp 32KB 835 5045 Modified SCAS test for insoluble and volatile chemicals PDF 7pp 19KB 835 5154 Anaerobic biodegradation in the subsurface PDF 12pp 31KB 835 5270 Indirect photolysis screening test Sunlight photolysis in waters containing dissolved humic substances PDF 24pp 78KB Series 840 Spray Drift Test Guidelines Final Guidelines The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations 840 1000 Background for Pesticide Aerial Drift Evaluation PDF 5pp 14KB 840 1100 Spray Droplet Size Spectrum PDF 7pp 18KB 840 1200 Spray Drift Field Deposition PDF 8pp 22KB Series 850 Ecological Effects Test Guidelines The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations Public Drafts Guidelines in Public Drafts Master Guideline List PDF 1p 9KB Summary of Changes PDF 10pp 22KB Series 850 Ecological Effects Test Guidelines Public Drafts The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations 1 850 1000 Special considerations for conducting aquatic laboratory studies 13pp 45KB 2 850 1010 Aquatic invetebrate acute toxicity test freshwater daphnids PDF 10pp 36KB 3 850 1020 Gammarid acute toxicity test PDF 11pp 36KB 4 850 1025 Oyster acute toxicity test shell deposition PDF 9pp 32KB 5 850 1035 Mysid acute toxicity test PDF 10pp 34KB 6 850 1045 Penaeid acute toxicity test PDF 9pp 32KB 7 850 1055 Bivalve acute toxicity test embryo larval PDF 7pp 27KB 8 850 1075 Fish acute toxicity test freshwater and marine PDF 13pp 45KB 9 850 1085 Fish acute toxicity mitigated by humic acid PDF 10pp 35KB 10 850 1300 Daphnid chronic toxicity test PDF 12pp 42KB 11 850 1350 Mysid chronic toxicity test PDF 10pp 36KB 12 850 1400 Fish early life stage toxicity test PDF 15pp 66KB 13 850 1500 Fish life cycle toxicity PDF 4pp 16KB 14 850 1710 Oyster BCF PDF 14pp 50KB 15 850 1730 Fish BCF PDF 25pp 74KB 16 850 1735 Whole sediment acute toxicity invertebrates freshwater PDF 19pp 65KB 17 850 1740 Whole sediment acute toxicity invertebrates marine PDF 14pp 50KB 18 850 1790 Chironomid sediment toxicity test PDF 16pp 57KB 19 850 1800 Tadpole sediment subchronic toxicity test PDF 15pp 49KB 20 850 1850 Aquatic food chain transfer PDF 4pp 16KB 21 850 1900 Generic freshwater microcosm test laboratory PDF 28pp 76KB 22 850 1925 Site specific aquatic microcosm test laboratory PDF 21pp 91KB 23 850 1950 Field testing for aquatic organisms PDF 7pp 21KB 24 850 2100 Avian acute oral toxicity test PDF 11pp 38KB 25 850 2200 Avian dietary toxicity test PDF 12pp 42KB 26 850 2300 Avian reproduction test PDF 16pp 53KB 27 850 2400 Wild mammal acute toxicity PDF 5pp 18KB 28 850 2450 Terrestrial soil core microcosm test PDF 19pp 123KB 29 850 2500 Field testing for terrestrial wildlife PDF 43pp 115KB 30 850 3020 Honey bee acute contact toxicity PDF 8pp 27KB 31 850 3030 Honey bee toxicity of residues on foliage PDF 6pp 23KB 32 850 3040 Field testing for pollinators PDF 5pp 18KB 33 850 4000 Background Nontarget plant testing PDF 15pp 50KB 34 850 4025 Target area phytotoxicity PDF 15pp 51KB 35 850 4100 Terrestrial plant toxicity Tier I seedling emergence PDF 8pp 29KB 36 850 4150 Terrestrial plant toxicity Tier I vegetative vigor PDF 8pp 28KB 37 850 4200 Seed germination root elongation toxicity test PDF 8pp 29KB 38 850 4225 Seedling emergence Tier II PDF 10pp 36KB 39 850 4230 Early seedling growth toxicity test PDF 9pp 33KB 40 850 4250 Vegetative vigor Tier II PDF 10pp 35KB 41 850 4300 Terrestrial plants field study Tier III PDF 8pp 27KB 42 850 4400 Aquatic plant toxicity test using Lemna spp Tiers I and II PDF 10pp 36KB 43 850 4450 Aquatic plants field study Tier III PDF 9pp 30KB 44 850 4600 Rhizobium legume toxicity PDF 14pp 73KB 45 850 4800 Plant uptake and translocation test PDF 13pp 35KB 46 850 5100 Soil microbial community toxicity test PDF 11pp 46KB 47 850 5400 Algal toxicity Tiers I and II PDF 11pp 42KB 48 850 6200 Earthworm subchronic toxicity test PDF 13pp 43KB 49 850 6800 Modified activated sludge respiration inhibition test for sparingly soluble chemicals PDF 9pp 37KB 50 850 7100 Data Reporting for Environmental Chemistry Methods PDF 9pp 30KB Series 860 Residue Chemistry Test Guidelines Public Drafts The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations 860 1000 Background PDF 40pp 133KB 860 1100 Chemical identity PDF 4pp 12KB 860 1200 Directions for use PDF 9pp 25KB 860 1300 Nature of the residue plants livestock PDF 37pp 103KB 860 1340 Residue analytical method PDF 12pp 31KB 860 1360 Multiresidue method PDF 4pp 13KB 860 1380 Storage stability data PDF 18pp 46KB 860 1400 Water fish irrigated crops PDF 5pp 14KB 860 1460 Food handling PDF 6pp 18KB 860 1480 Meat milk poultry eggs PDF 18pp 46KB 860 1500 Crop field trials PDF 90pp 309KB 860 1520 Processed food feed PDF 18pp 52KB 860 1550 Proposed tolerances PDF 5pp 16KB 860 1560 Reasonable grounds in support of the petition PDF 3pp 11KB 860 1650 Submittal of analytical reference standards PDF 4pp 12KB 860 1850 Confined accumulation in rotational crops PDF 12pp 43KB 860 1900 Field accumulation in rotational crops PDF 10pp 27KB Series 860 Residue Chemistry Test Guidelines Final Guidelines The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations You will need Adobe Reader to view some of the files on this page See EPA s PDF page to learn more 860 1000 Background PDF 42pp 128KB 860 1100 Chemical identity PDF 3pp 11KB 860 1200 Directions for use PDF 9pp 29KB 860 1300 Nature of the residue plants livestock PDF 34pp 126KB 860 1340 Residue analytical method PDF 14pp 45KB 860 1360 Multiresidue method PDF 4pp 14KB 860 1380 Storage stability data PDF 17pp 54KB 860 1400 Water fish irrigated crops PDF 5pp 16KB 860 1460 Food handling PDF 6pp 20KB 860 1480 Meat milk poultry eggs PDF 16pp 53KB 860 1500 Crop field trials PDF 91pp 369KB 860 1520 Processed food feed PDF 17pp 64KB 860 1550 Proposed tolerances PDF 5pp 17KB 860 1560 Reasonable grounds in support of the petition PDF 3pp 11KB 860 1650 Submittal of analytical reference standards PDF 3pp 12KB 860 1850 Confined accumulation in rotational crops PDF 12pp 55KB 860 1900 Field accumulation in rotational crops PDF 11pp 39KB Series 870 Health Effects Test Guidelines Public Drafts The harmonized test guidelines have been developed for use in the testing of pesticides and toxic substances and the development of test data that must be submitted to the Agency for review under Federal regulations 870 1000 Acute toxicity testing background PDF 6pp 19KB 870 1100 Acute oral toxicity PDF 9pp 33KB 870 1200 Acute dermal toxicity PDF 9pp 33KB 870 1300 Acute inhalation toxicity PDF 11pp 19KB 870 1350 Acute inhalation toxicity with histopathology PDF 12pp 41KB 870 2400 Acute eye irritation PDF 7pp 26KB 870 2500 Acute dermal irritation PDF 10pp 35KB 870 2600 Skin sensitization PDF 8pp 29KB 870 3100 90 Day oral toxicity PDF 12p