Mupirocin-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEMupirocin(Standard)Cat.No.:HY-B0958RCASNo.:12650-69-0分子式:C??H??O?分子量:500.62作用靶點(diǎn):Bacterial;Antibiotic作用通路:Anti-infection儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性 Mupirocin(Standard)是Mupirocin的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。Mupirocin(BRL-4910A，Pseudomonicacid)可從Pseudomonasfluorescens中分離得到，是一種有口服活性的抗生素。Mupirocin通過可逆地抑制異亮氨酸轉(zhuǎn)移RNA，從而抑制細(xì)菌蛋白和RNA的合成而發(fā)揮抗菌作用。REFERENCESSutherlandR,etal.Antibacterialactivityofmupirocin(pseudomonicacid),anewantibioticfortopicaluse.AntimicrobAgentsChemother.1985Apr;27(4):495-8.ParentiMA,etal.Mupirocin:atopicalantibioticwithauniquestructureandmechanismofaction.ClinPharm.1987Oct;6(10):761-70.VingsboLundbergC,etal.Efficacyoftopicalandsystemicantibiotictreatmentofmeticillin-resistantStaphylococcusaureusinamurinesuperficialskinwoundinfectionmodel.IntJAntimicrobAgents.2013Sep.42(3):272-5.MohammadH,AbutalebNS,DieterlyAM,LyleLT,SeleemMN.Investigatingauranofinforthetreatmentofinfecteddiabeticpressureulcersinmiceanddermaltoxicityinpigs.SciRep.2021May25;11(1):10935.GiacomettiA,etal.Mupirocinprophylaxisagainstmethicillin-susceptible,methicillin-resistant,orvancomycin-intermediateStaphylococcusepidermidisvascular-graftinfection.AntimicrobAgentsChemother.2000Oct.44(10):2842-4.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792/p>