Methylene-Blue-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEMethyleneBlue(Standard)Cat.No.:HY-14536RCASNo.:61-73-4分?式:C??H??ClN?S分?量:319.85作?靶點(diǎn):GuanylateCyclase;MonoamineOxidase;NOSynthase;Microtubule/Tubulin作?通路:GPCR/GProtein;NeuronalSignaling;

Immunology/Inflammation;CellCycle/DNADamage;

Cytoskeleton儲(chǔ)存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性MethyleneBlue(Standard)MethyleneBlue的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。Methyleneblue(BasicBlue9)?種鳥苷酸環(huán)化酶(sGC)，單胺氧化酶A(MAO-A)和NO合酶(NOS)抑制劑。Methyleneblueblue通過?氧化氮合成酶/鳥苷酸環(huán)化酶信號(hào)通路降低脈沖前抑制。Methyleneblue?種氧化還原循環(huán)化合物，能夠穿過?腦屏障。MethyleneblueTau聚集抑制劑。亞甲藍(lán)可減輕腦?腫，減弱?膠質(zhì)細(xì)胞活化，減少神經(jīng)炎癥。IC50&TargetGuanylylcyclase(sGC)[1].MonoamineoxidaseA(MAO-A)[1].NOsynthase(NOS)[1]REFERENCES[1].KlamerD,et,al.Phencyclidine-inducedbehaviourinmicepreventedbymethyleneblue.BasicClinPharmacolToxicol.2004Feb;94(2):65-72.[2].Hochgr?feK,et,al.Preventivemethylenebluetreatmentpreservescognitioninmiceexpressingfull-lengthpro-aggreganthumanTau.ActaNeuropatholCommun.2015May10;3:25.[3].FennAM,et,al.Methyleneblueattenuatestraumaticbraininjury-associatedneuroinflammationandacutedepressive-likebehaviorinmice.JNeurotrauma.2015Jan15;32(2):127-38.McePdfHeihtCaution:Producthasnotbeenfullyvalidatedformedicalapplications.gForresearchuseonly.Tel:400-820-3792ax:0