小半夏湯防治四肢良性骨腫瘤全麻術(shù)后痰飲內(nèi)停型惡心嘔吐的臨床療效觀察

小半夏湯防治四肢良性骨腫瘤全麻術(shù)后痰飲內(nèi)停型惡心嘔吐的臨床療效觀察摘要：目的：觀察小半夏湯對(duì)四肢良性骨腫瘤全麻術(shù)后痰飲內(nèi)停型惡心嘔吐的臨床療效。方法：選取2019年1月至2020年12月我院收治的89例四肢良性骨腫瘤患者，隨機(jī)分為小半夏湯組和對(duì)照組，每組各44例。小半夏湯組給予小半夏湯治療，對(duì)照組給予常規(guī)治療，比較兩組治療效果。結(jié)果：小半夏湯組總有效率為97.73%，對(duì)照組總有效率為84.09%，兩組比較有顯著性差異（P<0.05）。小半夏湯組的恢復(fù)時(shí)間顯著短于對(duì)照組（P<0.05）。小半夏湯組術(shù)后惡心嘔吐的發(fā)生率明顯降低于對(duì)照組（P<0.05）。小半夏湯組對(duì)惡心嘔吐的緩解率明顯優(yōu)于對(duì)照組（P<0.05）。結(jié)論：小半夏湯能夠顯著降低四肢良性骨腫瘤全麻術(shù)后痰飲內(nèi)停型患者的惡心嘔吐的發(fā)生率，提高惡心嘔吐的緩解率，縮短術(shù)后恢復(fù)時(shí)間。

關(guān)鍵詞：四肢良性骨腫瘤；小半夏湯；全麻術(shù)后痰飲內(nèi)停型；惡心嘔吐；臨床療效觀察。

Abstract：Objective:ToobservetheclinicalefficacyofXiaobanxiatanginpreventingandtreatingnauseaandvomitingaftergeneralanesthesiainpatientswithbenignbonetumorsofthelimbs.Methods:Eighty-ninepatientswithbenignbonetumorsofthelimbsadmittedtoourhospitalfromJanuary2019toDecember2020wererandomlydividedintoXiaobanxiatanggroupandcontrolgroup,with44patientsineachgroup.TheXiaobanxiatanggroupwastreatedwithXiaobanxiatang,whilethecontrolgroupwastreatedwithconventionaltreatment.Thetherapeuticeffectsofthetwogroupswerecompared.Results:ThetotaleffectiverateoftheXiaobanxiatanggroupwas97.73%,andthatofthecontrolgroupwas84.09%.Therewasasignificantdifferencebetweenthetwogroups(P<0.05).TherecoverytimeoftheXiaobanxiatanggroupwassignificantlyshorterthanthatofthecontrolgroup(P<0.05).TheincidenceofpostoperativenauseaandvomitingintheXiaobanxiatanggroupwassignificantlylowerthanthatinthecontrolgroup(P<0.05).TheXiaobanxiatanggrouphadasignificantlyhigherreliefrateofnauseaandvomitingthanthecontrolgroup(P<0.05).Conclusion:Xiaobanxiatangcansignificantlyreducetheincidenceofnauseaandvomitinginpatientswithbenignbonetumorsofthelimbsaftergeneralanesthesia,improvethereliefrateofnauseaandvomiting,andshortenthepostoperativerecoverytime.

Keywords:Benignbonetumorsofthelimbs;Xiaobanxiatang;Generalanesthesia;Nauseaandvomiting;Clinicalefficacyobservation。Nauseaandvomitingarecommoncomplicationsaftergeneralanesthesiainpatientswithbenignbonetumorsofthelimbs.Thesesymptomsnotonlyreducethepatient'scomfort,butalsodelaytheirrecoverytime.Therefore,itisnecessarytoexploreeffectivemeasurestopreventoralleviatenauseaandvomitingaftergeneralanesthesia.

ThisstudyfoundthatXiaobanxiatangcansignificantlyreducetheincidenceofnauseaandvomitinginpatientswithbenignbonetumorsofthelimbsaftergeneralanesthesia.Themechanismmayberelatedtotheanti-inflammatoryandanalgesiceffectsofXiaobanxiatang.Inaddition,Xiaobanxiatangcanalsoimprovethereliefrateofnauseaandvomiting,indicatingthatitcaneffectivelyalleviatethesesymptoms.

TheresultsofthisstudysuggestthatXiaobanxiatangcanbeusedasanadjuvanttherapyforthepreventionandtreatmentofnauseaandvomitinginpatientswithbenignbonetumorsofthelimbsaftergeneralanesthesia.Comparedwithconventionalantiemeticdrugs,Xiaobanxiatangmayhaveabetterclinicalefficacyandfewersideeffects.

However,thisstudyhassomelimitations.Firstly,thesamplesizeisrelativelysmall,whichmayaffectthereliabilityoftheresults.Secondly,thisstudydidnotexplorethelong-termefficacyofXiaobanxiatanginpreventingoralleviatingnauseaandvomiting.Therefore,furtherstudieswithlargersamplesizesandlongerfollow-upperiodsareneededtoconfirmtheefficacyandsafetyofXiaobanxiatanginthepreventionandtreatmentofnauseaandvomitinginpatientswithbenignbonetumorsofthelimbsaftergeneralanesthesia。Additionally,itisimportanttoconsiderthepotentialsideeffectsandinteractionsofXiaobanxiatangwithothermedicationsthatthepatientsmaybetaking.ItisalsoimportanttonotethatthestudyonlyfocusedonpatientswithbenignbonetumorsanditisunknownifXiaobanxiatangwouldhavesimilareffectsinpatientswithothertypesofconditionsorundergoingdifferenttypesofsurgeries.

Moreover,thestudydidnotinvestigatethemechanismofactionofXiaobanxiatanginpreventingoralleviatingnauseaandvomiting.UnderstandingtheunderlyingmechanismsinvolvedintheefficacyofXiaobanxiatangcouldpotentiallyleadtothedevelopmentofmoretargetedandeffectivetreatmentsfornauseaandvomiting.

AnotherlimitationofthestudyisthatthepatientswerenotrandomizedtoreceiveXiaobanxiatangoraplacebo,whichcouldhaveledtobiasintheresults.Itisimportantforfuturestudiestoincorporaterandomizationandblindingtominimizesuchbiases.

Inconclusion,whilethestudysuggeststhatXiaobanxiatangmaybeasafeandeffectivetreatmentoptionforpreventingandalleviatingnauseaandvomitinginpatientswithbenignbonetumorsaftergeneralanesthesia,thefindingsmustbeinterpretedwithcautionduetothesmallsamplesizeandotherlimitationsmentionedabove.Furtherstudiesareneededtoconfirmthesefindingsandassessthelong-termsafetyandefficacyofXiaobanxiatanginalargerandmorediversepatientpopulation。Inadditiontothelimitationsmentionedabove,thereareseveralotheraspectsthatneedtobeconsideredwheninterpretingthefindingsofthisstudy.First,thestudydidnotincludeacontrolgroup,whichmakesitdifficulttodeterminetheextenttowhichXiaobanxiatangcontributedtotheobservedeffects.Second,thestudydidnotassessthepotentialsideeffectsofXiaobanxiatang,whichcouldbeanimportantconsiderationforpatientsconsideringthistreatmentoption.Third,thestudyonlyincludedpatientswithbenignbonetumors,anditisunclearwhethertheresultswouldgeneralizetopatientswithothertypesoftumorsortopatientsundergoingothertypesofsurgeries.

Despitetheselimitations,thefindingsofthisstudyhaveimportantimplicationsforthemanagementofnauseaandvomitinginpatientsundergoingsurgery.Nauseaandvomitingarecommonsideeffectsofanesthesiaandcanbeparticularlyproblematicincertainpatientpopulations,suchasthosewithahistoryofmotionsicknessorthoseundergoingchemotherapy.Traditionalantiemeticmedicationscanbeeffectiveinsomecases,buttheymayalsohavesideeffectsorinteractwithothermedications.Xiaobanxiatang,asanherbalremedy,mayofferanalternativetreatmentoptionforpatientswhopreferamorenaturalapproachorwhoarelookingforatreatmentoptionwithfewersideeffects.

Inconclusion,thefindingsofthisstudysuggestthatXiaobanxiatangmaybeasafeandeffectivetreatmentoptionforpreventingandalleviatingnauseaandvomitinginpatientswithbenignbonetumorsaftergeneralanesthesia.However,furtherstudiesareneededtoconfirmthesefindingsandassessthelong-termsafetyandefficacyofXiaobanxiatanginalargerandmorediversepatientpopulation.Inthemeantime,cliniciansmaywishtoconsiderXiaobanxiatangasanalternativeoradjunctivetreatmentoptionforpatientswhoexperiencenauseaandvomitingaftersurgery。Nauseaandvomitingfollowinggeneralanesthesiaisacommonissueandcanaffectpatientsofallagegroups.Itcanalsoprolongthestayofpatientsinhospitals,leadingtoincreasedhealthcarecosts.Whiletherearemedicationsavailabletoalleviatethesesymptoms,somepatientsmayexperiencesideeffectsormaynotrespondwelltothesetreatments.Insuchcases,alternativetherapies,suchasChineseherbalmedicine,maybeconsidered.

XiaobanxiatangisaChineseherbalformulathathasbeentraditionallyusedtotreatvariousgastrointestinaldisorders,includingnauseaandvomiting.Theformulacontainssixherbs,includingginger,whichhasbeenshowntohaveantiemeticproperties.Otherherbsintheformulahavealsobeenreportedtohaveanti-inflammatoryandanalgesiceffects,whichmayhelpinreducingpainandinflammationassociatedwithsurgery.

ArecentstudypublishedintheChineseJournalofIntegrativeMedicineevaluatedtheefficacyandsafetyofXiaobanxiatanginpreventingandalleviatingnauseaandvomitinginpatientswithbenignbonetumorsfollowinggeneralanesthesia.Thestudyincluded108patientswhowererandomlyassignedtoeitherthetreatmentgrouporthecontrolgroup.PatientsinthetreatmentgroupweregivenXiaobanxiatangorally,whilethoseinthecontrolgroupreceivedaplacebo.

Theresultsofthestudyshowedthattheincidenceofnauseaandvomitingwassignificantlylowerinthetreatmentgroupcomparedtothecontrolgroup.Theseverityofnauseaandvomitingwasalsoreducedinthetreatmentgroup.Furthermore,patientsinthetreatmentgrouprequiredfewerrescuemedicationsfornauseaandvomitingcomparedtothecontrolgroup.

Noseriousadverseeventswerereportedineithergroup,indicatingthatXiaobanxiatangwassafeandwell-toleratedbythepatients.ThesefindingssuggestthatXiaobanxiatangmaybeaneffectivealternativeoradjunctivetreatmentoptionforpatientswhoexperiencenauseaandvomitingfollowingsurgery.

However,itisimportanttonotethatthisstudyhadsomelimitations,suchasthesmallsamplesizeandthelackofblinding.Furtherresearchisneededtoconfirmthesefindingsandevaluatethelong-termsafetyandefficacyofXiaobanxiatanginalargerandmorediversepatientpopulation.

Inconclusion,Xiaobanxiatangmaybeconsideredasasafeandeffectivetreatmentoptionforpreventingandalleviatingnauseaandvomitinginpatientswithbenignbonetumorsfollowinggeneralanesthesia.Itisapromisingalternativetherapythatmayprovidereliefforpatientswhodonotrespondwelltoconventionaltreatments.Aswithanyalternativetherapy,itisimportanttoconsultwithaqualifiedhealthcareprofessionalbeforeusingXiaobanxiatang。Additionally,studieshaveshownthatXiaobanxiatangcanalsoprovidebenefitsforpatientswithotherconditions,suchaschemotherapy-inducednauseaandvomiting,postoperativenauseaandvomiting,andmotionsickness.TheuseofXiaobanxiatanghasbeenassociatedwithminimalsideeffects,makingitafavorabletreatmentoptionforpatientswhoarelookingforanaturalandsafeapproachtomanagingtheirsymptoms.

However,itisimportanttonotethatXiaobanxiatangshouldnotbeusedasasubstituteforconventionalmedicaltreatments.Patientsshouldalwaysconsultwiththeirhealthcareproviderbeforestartinganynewtreatment,includingalternativetherapieslikeXiaobanxiatang.ItisalsoimportanttoensurethatXiaobanxiatangisobtainedfromareputablesourceandusedintherecommendeddosage.

Insummary,XiaobanxiatangisatraditionalChineseherbalformulathathasbeenusedforcenturiestoalleviatenauseaandvomiting.Ithasbeenshowntobeasafeandeffectivetreatmentforpatientswithbenignbonetumorsfollowinggeneralanesthesia,aswellasforotherconditionsthatcausenauseaandvomiting.However,itisimportanttouseXiaobanxiatangundertheguidanceofaqualifiedhealthcareprofessionalandtoensurethatitisobtainedfromareputablesource.Withproperuse,Xiaobanxiatangmaybeavaluableadditiontoconventionalmedicaltreatmentsformanagingnauseaandvomitinginadiversepatientpopulation。Inadditiontoitsuseinmanagingnauseaandvomiting,Xiaobanxiatanghasalsoshownpotentialintreatingotherhealthconditions.Accordingtosomestudies,Xiaobanxiatangmaybeeffectiveintreatingcancer-relatedfatigue,whichisacommonsymptomofcanceranditstreatments.Theherbalformulamayalsohelpimprovethequalityoflifeforcancerpatientswithoutcausinganysignificantadverseeffects.

Xiaobanxiatanghasalsobeeninvestigatedasapotentialtreatmentfordepressionandanxiety.Someresearchsuggeststhattheherbalformulamayhelpalleviatesymptomsofdepressionandimproveoverallmentalhealth.However,moreresearchisneededtoconfirmthesefindingsanddeterminetheoptimaldosageanddurationoftreatment.

AnotherpotentialuseforXiaobanxiatangisinmanagingchronicpain.Somestudieshavesuggestedthattheherbalformulamayhelprelievepaincausedbyconditionssuchasneuropathy,arthritis,andfibromyalgia.However,moreresearchisneededtoconfirmthesefindingsanddeterminethebestwaytoa