卵巢性索間質(zhì)腫瘤課件

卵巢性索-間質(zhì)腫瘤卵巢性索-間質(zhì)腫瘤1分化及分類●女性性索分化層細(xì)胞露:66%卵泡纖維瘤組:28%卵泡膜、纖維輯/肉瘤化性間質(zhì)3%兩性混合分化兩性母細(xì)胞、環(huán)管狀性索瘤親分性索質(zhì)腫瘤類固醵細(xì)胞分化leydig細(xì)胞瘤、聞質(zhì)黃瘤非特異性類固酸細(xì)胞男性性素分化夜持Leydig細(xì)胞:1%間質(zhì)Lydg細(xì)胞瘤分化及分類2粒層細(xì)胞癟(GcT。單純由或>]0%的明粒層細(xì)胞組成禮景常為纖雄卵泡膜瘤樣●具有惡性潛能10%50%可氯發(fā)分型成年型和幼年型粒層細(xì)胞癟(GcT3(-減年型(AGcT1占卵粒層細(xì)胞瘤的95%2年齡:中年至絕經(jīng)期婦女(>40y)3大體:多為單側(cè)(95%),分葉狀切面黃色實(shí)性/竇性可伴出血媧死(-減年型(AGcT44鏡下所見:奧型粒層細(xì)胞:胞漿少,被成卵圓形飛見核溝,被分<1-2/10HPF黃素化懂酸性或空泡狀胞漿,失去特征性溝偶見奇異形核:不影購預(yù)后排列高分化:微(ca|-Exner小體/巨濾泡啼分化:島狀狀低分化:緞帶樣、彌漫漫潤(rùn)(肉瘤樣)間質(zhì):纖雄卵泡膜樣。可伴局灶藏璃樣變4鏡下所見:5粒層細(xì)胞瘤:2teSsa%粒層細(xì)胞瘤6[rmor,mirch和g。26[rmor,mirch7tumoryththadrionodFig.26.11Well-ditferentiatedFig-26.12Wwl-citferentiatedgranulosacelltuscumisimportatumoryththadrionodFig.268題F|g.26.14ellsor(B)smallspindledcells.題95.粒層綱胞磨變異型:1)TubularpatterneTubulesindistinguishablefromthoseofasertolicelltumorarepresentoButtubulesarealmostinvariablyminor5.粒層綱胞磨變異型:10卵巢性索間質(zhì)腫瘤課件11卵巢性索間質(zhì)腫瘤課件12卵巢性索間質(zhì)腫瘤課件13卵巢性索間質(zhì)腫瘤課件14卵巢性索間質(zhì)腫瘤課件15卵巢性索間質(zhì)腫瘤課件16卵巢性索間質(zhì)腫瘤課件17卵巢性索間質(zhì)腫瘤課件18卵巢性索間質(zhì)腫瘤課件19卵巢性索間質(zhì)腫瘤課件20卵巢性索間質(zhì)腫瘤課件21卵巢性索間質(zhì)腫瘤課件22卵巢性索間質(zhì)腫瘤課件23卵巢性索間質(zhì)腫瘤課件24卵巢性索間質(zhì)腫瘤課件25卵巢性索間質(zhì)腫瘤課件26卵巢性索間質(zhì)腫瘤課件27卵巢性索間質(zhì)腫瘤課件28卵巢性索間質(zhì)腫瘤課件29卵巢性索間質(zhì)腫瘤課件30卵巢性索間質(zhì)腫瘤課件31卵巢性索間質(zhì)腫瘤課件32卵巢性索間質(zhì)腫瘤課件33卵巢性索間質(zhì)腫瘤課件34卵巢性索間質(zhì)腫瘤課件35卵巢性索間質(zhì)腫瘤課件36卵巢性索間質(zhì)腫瘤課件37卵巢性索間質(zhì)腫瘤課件38卵巢性索間質(zhì)腫瘤課件39卵巢性索間質(zhì)腫瘤課件40卵巢性索間質(zhì)腫瘤課件41卵巢性索間質(zhì)腫瘤課件42卵巢性索間質(zhì)腫瘤課件43卵巢性索間質(zhì)腫瘤課件44卵巢性索間質(zhì)腫瘤課件45卵巢性索間質(zhì)腫瘤課件46卵巢性索間質(zhì)腫瘤課件47卵巢性索間質(zhì)腫瘤課件48卵巢性索間質(zhì)腫瘤課件49卵巢性索間質(zhì)腫瘤課件50卵巢性索間質(zhì)腫瘤課件51卵巢性索間質(zhì)腫瘤課件52卵巢性索間質(zhì)腫瘤課件53卵巢性索間質(zhì)腫瘤課件54卵巢性索間質(zhì)腫瘤課件55卵巢性索間質(zhì)腫瘤課件56卵巢性索間質(zhì)腫瘤課件57卵巢性索間質(zhì)腫瘤課件58卵巢性索間質(zhì)腫瘤課件59卵巢性索-間質(zhì)腫瘤卵巢性索-間質(zhì)腫瘤60分化及分類●女性性索分化層細(xì)胞露:66%卵泡纖維瘤組:28%卵泡膜、纖維輯/肉瘤化性間質(zhì)3%兩性混合分化兩性母細(xì)胞、環(huán)管狀性索瘤親分性索質(zhì)腫瘤類固醵細(xì)胞分化leydig細(xì)胞瘤、聞質(zhì)黃瘤非特異性類固酸細(xì)胞男性性素分化夜持Leydig細(xì)胞:1%間質(zhì)Lydg細(xì)胞瘤分化及分類61粒層細(xì)胞癟(GcT。單純由或>]0%的明粒層細(xì)胞組成禮景常為纖雄卵泡膜瘤樣●具有惡性潛能10%50%可氯發(fā)分型成年型和幼年型粒層細(xì)胞癟(GcT62(-減年型(AGcT1占卵粒層細(xì)胞瘤的95%2年齡:中年至絕經(jīng)期婦女(>40y)3大體:多為單側(cè)(95%),分葉狀切面黃色實(shí)性/竇性可伴出血媧死(-減年型(AGcT634鏡下所見:奧型粒層細(xì)胞:胞漿少,被成卵圓形飛見核溝,被分<1-2/10HPF黃素化懂酸性或空泡狀胞漿,失去特征性溝偶見奇異形核:不影購預(yù)后排列高分化:微(ca|-Exner小體/巨濾泡啼分化:島狀狀低分化:緞帶樣、彌漫漫潤(rùn)(肉瘤樣)間質(zhì):纖雄卵泡膜樣?？砂榫衷畈亓幼?鏡下所見:64粒層細(xì)胞瘤:2teSsa%粒層細(xì)胞瘤65[rmor,mirch和g。26[rmor,mirch66tumoryththadrionodFig.26.11Well-ditferentiatedFig-26.12Wwl-citferentiatedgranulosacelltuscumisimportatumoryththadrionodFig.2667題F|g.26.14ellsor(B)smallspindledcells.題685.粒層綱胞磨變異型:1)TubularpatterneTubulesindistinguishablefromthoseofasertolicelltumorarepresentoButtubulesarealmostinvariablyminor5.粒層綱胞磨變異型:69卵巢性索間質(zhì)腫瘤課件70卵巢性索間質(zhì)腫瘤課件71卵巢性索間質(zhì)腫瘤課件72卵巢性索間質(zhì)腫瘤課件73卵巢性索間質(zhì)腫瘤課件74卵巢性索間質(zhì)腫瘤課件75卵巢性索間質(zhì)腫瘤課件76卵巢性索間質(zhì)腫瘤課件77卵巢性索間質(zhì)腫瘤課件78卵巢性索間質(zhì)腫瘤課件79卵巢性索間質(zhì)腫瘤課件80卵巢性索間質(zhì)腫瘤課件81卵巢性索間質(zhì)腫瘤課件82卵巢性索間質(zhì)腫瘤課件83卵巢性索間質(zhì)腫瘤課件84卵巢性索間質(zhì)腫瘤課件85卵巢性索間質(zhì)腫瘤課件86卵巢性索間質(zhì)腫瘤課件87卵巢性索間質(zhì)腫瘤課件88卵巢性索間質(zhì)腫瘤課件89卵巢性索間質(zhì)腫瘤課件90卵巢性索間質(zhì)腫瘤課件91卵巢性索間質(zhì)腫瘤課件92卵巢性索間質(zhì)腫瘤課件93卵巢性索間質(zhì)腫瘤課件94卵巢性索間質(zhì)腫瘤課件95卵巢性索間質(zhì)腫瘤課件96卵巢性索間質(zhì)腫瘤課件97卵巢性索間質(zhì)腫瘤課件98卵巢性索間質(zhì)腫瘤課件99卵巢性索間質(zhì)腫瘤課件100卵巢性索間質(zhì)腫瘤課件101卵巢性索間質(zhì)腫瘤課件102卵巢性索間質(zhì)腫瘤課件103卵巢性索間質(zhì)腫瘤課件104卵巢性索間質(zhì)腫瘤課件105卵巢性索間質(zhì)腫瘤課件106卵巢性索間質(zhì)腫瘤課件107卵巢性索