Spermine-NSC-268508-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESpermineCat. No.: HY-B1777CAS No.: 71-44-3Synonyms: NSC 268508; Neuridine分式: CHN分量: 202.34作靶點(diǎn): Endogenous Metabolite作通路: Metabolic Enzyme/Protease儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) H2

2、O : 165 mg/mL (815.46 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 4.9422 mL 24.7109 mL 49.4218 mL5 mM 0.9884 mL 4.9422 mL 9.8844 mL10 mM 0.4942 mL 2.4711 mL 4.9422 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Spermine (NSC 268508) 作為個(gè)直接的由除劑，能夠保護(hù) DNA

3、 免受由基的攻擊。IC50 & Target Human Endogenous Metabolite體外研究Spermine (NSC 268508) at physiologically relevant concentrations inhibits ROS-induced DNA damage, withmaximal inhibition observed at 1 to 2 mM. These concentrations are well within the estimates for the1/2 Master of Small Molecules 您邊的抑制劑師www.Med

4、ChemEphysiological concentrations of spermine 1.REFERENCES1. Ha HC, et al. The natural polyamine spermine functions directly as a free radical scavenger. Proc Natl Acad Sci U S A. 1998 Sep15;95(19):11140-5.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 021-5