Sodium-ionophore-III-ETH2120-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESodium ionophore IIICat. No.: HY-101109CAS No.: 81686-22-8Synonyms: ETH2120分式: CHNO分量: 552.79作靶點(diǎn): Sodium Channel作通路: Membrane Transporter/Ion Channel儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn)

2、 DMSO : 1 mg/mL (1.81 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 1.8090 mL 9.0450 mL 18.0901 mL5 mM - - -10 mM - - -請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請根據(jù)您的實(shí)驗(yàn)動物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次添加助溶?為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該

3、溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： corn oilSolubility: 2 mg/mL (3.62 mM); Suspended solution; Need ultrasonicBIOLOGICAL ACTIVITY1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE物活性 Sodium ionophore III (ETH2120)適于測定液、漿、清中的鈉活性的Na+載體。體外研究 Preincubation of the cells with the Na+ ionophore sodium ionophore I

4、II not only stimulated caffeate reduction,but completely abolished ATP synthesis. Addition of sodium ionophore III to cells in the steady state of caffeatereduction immediately dissipated the intracellular ATP level 1. Lactate-sulfate grown cells are insensitive tothe Na+ ionophore, ETH2120 2. Sodiu

5、m ionophore III ligand is a very effective receptor for the Eu3+ andAm3+ cations and can be considered as a potential extraction agent for nuclear iste treatment 3.REFERENCES1. Imkamp F, et al. Chemiosmotic energy conservation with Na(+) as the coupling ion during hydrogen-dependent caffeate reducti

6、on byAcetobacterium woodii. J Bacteriol. 2002 Apr;184(7):1947-51.2. Wang L, et al. The role of Rnf in ion gradient formation in Desulfovibrio alaskensis. PeerJ. 2016 Apr 14;4:e1919.3. Makrlk, E, et al. Sodium Ionophore III as Very Effective Receptor for Trivalent Europium and Americium.J Solution Chem (2016) 45:463.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 4