E-2-Decenoic-acid-trans-2-Decenoic-acid-DataSheet-生命科學(xué)試劑-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE(E)-2-Decenoic acidCat. No.: HY-13211CAS No.: 334-49-6Synonyms: trans-2-Decenoic acid分式: CHO分量: 170.25作靶點: Others作通路: Others儲存式: Pure form -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實驗 DMSO : 100 mg/mL (587

2、.37 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 5.8737 mL 29.3686 mL 58.7372 mL5 mM 1.1747 mL 5.8737 mL 11.7474 mL10 mM 0.5874 mL 2.9369 mL 5.8737 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實驗請根據(jù)您的實驗動物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次添加助溶?為保證實驗結(jié)果的可靠性，體內(nèi)實驗的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；

3、澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (14.68 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (14.68 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oil1/2 Master of Sma

4、ll Molecules 您邊的抑制劑師www.MedChemESolubility: 2.5 mg/mL (14.68 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 (E)-2-Decenoic acid蜂王漿中的種脂肪酸。體外研究 (E)-2-Decenoic acid is isolated along with 10-hydroxy-trans-2-decenoic acid, a fatty acid unique to royal jelly.(E)-2-Decenoic acid and 10-hydroxy-trans-2-decenoic

5、 acid are both described to demonstrate estrogenicactivity, where the fatty acids demonstrate inhibition of 17-estradiol binding to estrogen receptor-.REFERENCES1. Naumowicz M, Petelska AD, Figaszewski ZA.Impedance analysis of complex formation equilibria in phosphatidylcholine bilayerscontaining de

6、canoic acid or decylamine.Cell Biochem Biophys. 2011 Sep;61(1):145-55.2. Kumar A, Singh S, Jain S, Kumar P.Synthesis, antimicrobial evaluation, QSAR and in Silico ADMET studies of decanoic acidderivatives.Acta Pol Pharm. 2011 Mar-Apr;68(2):191-204.3. Petelska AD, Figaszewski ZA.Interfacial tension o

7、f the lipid membrane formed from phosphatidylcholine-decanoic acid andphosphatidylcholine-decylamine systems.J Membr Biol. 2011 May;241(2):103-8.4. Hattori N et al.Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitorcells in vitro. Biomed Res. 2007 Oct;28(5):261-6.5. Suzuki KM et al. Estrogenic activities of Fatty acids and a sterol isolated from royal jelly. Evid Based Complement Alternat Med. 2008Sep;5(3):295-302.McePdfHeightCaution: Product has not been fully validated for medical applications.For r