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1、藥理學(xué)復(fù)習(xí)試題2(Pharmacological review questions 2)Pharmacological review questions 3The twenty-fifth chapter, Digestive System PharmacologyFirst, individual choice questionsEach of the following questions has five alternative answers: A, B, C, D, and E. Please choose the best answer from it.?1, does not b
2、elong to the peptic ulcer medicine is:A, lactasin?B, three magnesium silicate?C, cimetidineD, droperidol, Xiping,?E, ranitidineStandard answer: A?2. The following incorrect application of sodium bicarbonate isA, promote the absorption of aspirin in the stomachB, less used for neutralizing gastric ac
3、idC, promote phenobarbital excretion from urineAntibacterial effect of D and gentamicinE and alkaline urine can prevent the precipitation of sulfa drugsStandard answer: A?3, inhibition of gastric acid secretion mechanism of cimetidineA, blocking M receptors?B, protect gastric mucous membrane,?C, blo
4、cking H1 receptors?D and promote PGE2 synthesis?E, blocking H2 receptorsStandard answer: E?4, what kind of situation can not use the antiemetic metoclopramide:A, vomiting caused by radiotherapy?B, vomiting caused by cisplatin?C sickness induced vomitingD, vomiting caused by gastrointestinal dysfunct
5、ion?Nausea and vomiting after E and major surgeryStandard answer: C?5, on the right is the domperidone:A, a peripheral D2 receptor blocker?B, prone to extrapyramidal reactions?C, for gastrointestinal dysfunction, vomitingD, can cure schizophrenia?Reflux esophagitis, EStandard answer: A?6, the pharma
6、cological effects of prazosin, including Xiping, include:A, which inhibits gastric acid secretion?B, reduce saliva secretion?C, relieve gastrointestinal spasmD, acceleration heart rate?E, promote gallbladder contraction, treat pancreatitisStandard answer: A?7, Magnesium Sulfate is cathartic mechanis
7、m of drug action:What is the role of A versus Ca2 ten?B activates Na eleven, K, ten, ATP enzymesC, dilated peripheral vesselsD, which forms hypertonic in the lumen and reduces water absorption?E, cholecystokinin secretion, promote intestinal peristalsis and secretionStandard answer: D?8 what is the
8、mechanism of action of metoclopramide associated with that receptor?:A, D2?B, H1?C, M1?D, 5-HT3?E, N2Standard answer: A9, acid inhibition is the strongestA and M receptor blockers?B, proton pump inhibitors?C and gastrin receptor blockers?D and H2 receptor blockersE and PG receptor blockersStandard a
9、nswer: B10. Vomiting caused by tumor chemotherapyA, metoclopramide,?B, domperidone?C, lactuloseD, cisapride?E, ondansetronStandard answer: E11. The following are lubricating laxativesA, sodium sulfate?B, rhubarb?C, phenolphthaleinD, liquid paraffin?E, not all of themStandard answer: DTwo, multiple-c
10、hoice questionsEach of the following questions has five alternative answers: A, B, C, D, and E.Please select all the correct answers from the alternative answer.1, to help digestion drugs are:A, pepsin?B, cisapride?C hydrotalciteD, lactasin?E, dilute hydrochloric acidStandard answer: ADEThe twenty-s
11、ixth chapter is respiratory system pharmacologyI. radio questionsEach of the following questions has five alternative answers: A, B, C, D, and E. Please choose the best answer from it.1. The common effects of aminophylline, sodium hyaluronate, nitrogen, Jostin and salbutamol are:A and increase cardi
12、ac output?B, direct relaxation of bronchial smooth muscle?C and excited B2 receptors?D and decreased histamine release?E has antiasthmatic effectStandard answer: E2 、 the action of salbutamol is characterized by:The A and the excitatory heart act like adrenaline, do they?The effect of B and B2 recep
13、tor is obviously larger than that of B1 receptorC, aerosol inhalation faster than isoproterenol?D, oral administration, faster than inhaled drugs,?E and blockade of alpha 1 receptor in bronchial mucosaStandard answer: B?3, sodium citrate is the main mechanism to prevent asthma attack:A, direct relax
14、ation of bronchial smooth muscle?B, a stable mast cell membrane, inhibits the release of an allergic mediatorC, blocking adenosine receptors?D, promote catecholamine release?E, agonist B receptorStandard answer: B?4, prevention of allergic asthma, the best choice:A, ephedrine,?B, aminophylline,?C, s
15、odium citrateD, salbutamol?E, epinephrineStandard answer: C5 、 the main mechanism of glucocorticoid treatment of asthma is:Does A increase the excitability of the central nervous system?B, B2 receptor on stimulated bronchial smooth muscleC, anti-inflammatory and antiallergicD activates adenylate cyc
16、lase.?E, blocking M receptorsStandard answer: C?6. The following statement is incorrect:A, expectorant drugs can make dilute sputum or phlegm dissolving, easy to coughB and expectorant can be used as an adjuvant for antitussive agentsC and expectorant promote the excretion of sputum, which can reduc
17、e the irritation of respiratory tract mucosa, and have indirect antitussive and antiasthmatic effectsD and expectorant can promote the secretion of bronchial gland, and have the function of controlling secondary infectionE and expectorant have weak antiseptic and disinfection effects, and can reduce
18、 the odor of sputumStandard answer: E7, the statement about codeine is incorrect:A should be controlled, and?B, for dry cough without phlegm?C and various types of cough can be appliedD and antitussive dose does not inhibit respiration,?E, repeated use of addictiveStandard answer: CTwo, multiple-cho
19、ice questionsEach of the following questions has five alternative answers: A, B, C, D, and E. Please select all the correct answers from the alternative answer.1 、 adrenergic agonists which can produce antiasthmatic effect:A, salbutamol?B, terbutaline,?C, ephedrineD, norepinephrine,?E and clenbutero
20、lStandard answer: ABCE2, selective agonist B2 receptor drugs have:A, salbutamol?B, terbutaline,?C, ephedrineD, norepinephrine,?E and clenbuterolStandard answer: ABEThe twenty-seventh chapter is histamine receptor blockerI. radio questionsEach of the following questions has five alternative answers:
21、A, B, C, D, and E. Please choose the best answer from it.1 which of the following drugs is not an H1 receptor antagonist?:A, astemizoleB, diphenhydramineC, flutter and sensitiveD, doubling TingE, promethazineStandard answer: D2, the central sedative effect of H1 receptor blocker is strongest:A, diph
22、enhydramineB, BuchliCD, MeclozineE, Chlorphenamine MaleateStandard answer: A?3, diphenhydramine, which one is wrong:A, can be used for insomnia patientsB can be used for the treatment of urticariaC is the H1 receptor blockerD, treatable gastric and duodenal ulcersE, can treat allergic rhinitisStanda
23、rd answer: D4. No central sedative H1 receptor blocker is:A, diphenhydramine?B, promethazine?C, astemizoleD, and ChlorphenamineE, chlorphenamineStandard answer: C?5. What is the most effective H1 receptor blocker?:A and bronchial asthmaB, skin and mucous membrane allergy symptomsC, serum feverD, ana
24、phylactic shockHenoch Schonlein purpura, EStandard answer: B6, H1 receptor blockers each statement, the error is that:A is mainly used in the treatment of allergic diseasesThe main agent for B is famotidineC can be used for the treatment of pregnancy vomitingD can be used in the treatment of allergi
25、c insomniaThe most common adverse effect of E is central inhibitionStandard answer: B?7, antihistamines, H1 receptor antagonists, pharmacological action is:A, which competes with histamine for H1 receptors, prevents histamine from binding to the H1 receptorB and histamine react chemically to make hi
26、stamine ineffectiveC has the opposite pharmacological action and exerts the physiological antagonism effectD can stabilize mast cell membrane and inhibit histamine releaseE, not all of themStandard answer: A8 、 the medicine used for duodenal ulcer and gastric ulcer is:A, histamineB, ranitidineC, dip
27、henhydramineD, MeclozineE, promethazineStandard answer: B9. The drug that blocks the gastric parietal cell H2 receptor is:A, cimetidineB, promethazineC, Si Shah BillyD, ondansetronE, pyrrolidineStandard answer: ATwo, multiple-choice questionsEach of the following questions has five alternative answe
28、rs: A, B, C, D, and E. Please select all the correct answers from the alternative answer.1 、 the main clinical application of H2 receptor blockerThe effects of A, patients received chemotherapy antiemetic drugsB and pathological gastric acid secretion increasedReflux esophagitis, CD and Zhuo AI synd
29、romeE, gastroduodenal ulcerStandard answer: BCDEThe twenty-ninth chapter adrenal cortex hormoneI. each of the following questions has five alternative answers: A, B, C, D, and E. Please choose the best answer from it.?1. What is wrong with the pharmacological action of glucocorticoids?:A has a stron
30、g and specific inhibitory effect on inflammation caused by various stimuliB has an inhibitory effect on many aspects of immune responseC and stimulate bone marrow functionD and large dosage have anti shock effectE can relieve the organisms reaction to bacterial endotoxinStandard answer: A?2 、 the ma
31、in mechanism of glucocorticoid in allergic bronchial asthma is:A, which inhibits the tissue damage caused by antigen antibody reaction and the inflammatory processB interferes with the complement and participates in the immune responseC inhibits the production of antibodies in the human body?D incre
32、ased the intracellular cAMP content significantlyE, direct dilation of bronchial smooth muscleStandard answer: A?3. The description of the role of glucocorticoids in the visible components of the blood is wrong:A, leukocytosis,?B, thrombocytosisC, lymphocyte increase,?D, hemoglobin increasedE and ne
33、utrophilic leukocytosisStandard answer: C?4. The effect of glucocorticoids on the blood and hematopoietic system is:A stimulates the hematopoiesis of the bone marrow?B, reduce RBC and HBC, which reduces neutrophils?D, reduce plateletsE and lymphocyte increaseStandard answer: A?5. Corticosteroids are
34、 used for chronic inflammation:A has a strong anti-inflammatory effect and promotes inflammation dissipation.?B, inhibit granulation tissue growth, prevent adhesions and scarsC promotes vasoconstriction and reduces permeability in the inflammatory regionD stabilize lysosomal membranes and reduce rel
35、ease of proteolytic enzymesE inhibited the release of four acid from peanut and reduced the synthesis of PG in inflammatory mediumStandard answer: B6. Corticosteroids are used for serious infections:A, use its powerful anti-inflammatory effect, relieve symptoms, and let the patient through the dange
36、rous periodB, with antibacterial and anti toxin effectsC, neutralizing poison resistant, improve the body of toxin toleranceD, which increases the contractility of the myocardium, helps the patient pass the critical periodE, to eliminate inflammation and allergic reactions to the bodyStandard answer
37、: A7 、 the combination of corticosteroids and antibiotics is the purpose of severe infection:A, enhance airframe defense capability,?B and enhance the antibacterial effect of antibioticsC and antagonism of some adverse reactions of antibiotics?D and enhance the excitability of organismE, which uses
38、hormones to relieve symptoms, passes through a critical period, and uses antibiotics to control infectionStandard answer: E?8, long-term application of glucocorticoids can cause:A, hyperkalemia?Hypoglycemia, BC? Hypercalcemia?D, central obesityE and phosphorus excretion decreasedStandard answer: D9.
39、 The main cause of glucocorticoid induced and increased infection is:A, insufficient dosage, unable to control symptomsB, which inhibits inflammation and immune response, decreases the defense capacity of the organismC causes many pathogenic microorganisms to reproduceD, the patient was insensitive
40、to the hormone and did not reflect the corresponding efficacyE, inhibiting the release of corticotropinStandard answer: B10 、 when acute severe toxic infection, glucocorticoid treatment is adopted:A, high dose intravenous drip?B, high dose intramuscular injectionC, small dosage, many times?D, a load
41、, and then give maintenanceE, for a long time and large dosageStandard answer: A11, glucocorticoid and protein metabolism related adverse reactions:A, full face, buffalo back, central obesityB causes or aggravates infectionC induces or aggravates gastric and duodenal ulcersD, osteoporosis, muscle at
42、rophy, slow healing of the woundE, hypertensionStandard answer: DTwo, multiple-choice questionsEach of the following questions has five alternative answers: A, B, C, D, and E. Please select all the correct answers from the alternative answer.?1. The effect of adrenocortical hormone on blood and hema
43、topoiesis:A stimulates the hematopoiesis of bone marrow, and?B, increase the red blood cell and hemoglobin contentC, large doses of platelets increase?The concentration of D and fibrinogen increasedThe number of E and neutrophils increased, but the ability of migration and phagocytosis decreasedStan
44、dard answer: ABCDE?2 、 the common adverse reaction of long-term application of glucocorticoid is:A, hypertensionB, arrhythmiaC, stomach, duodenal ulcerD and renal impairmentE causes or aggravates infectionStandard answer: ACE3. Glucocorticoids are forbidden to:A, severe mental illness?B, active pept
45、ic ulcer, recent gastrointestinal anastomosisC, fracture, repair stageD, severe hypertension, diabetes mellitusE, an infection that can not be controlled by antibiotics, such as viruses or fungal infectionsStandard answer: ABCDE?Three, thinkingClinical application of glucocorticoidsThe thirty-fourth
46、 chapter: overview of antibacterial drugsI. radio questionsEach of the following questions has five alternative answers: A, B, C, D, and E. Please choose the best answer from it.?1, inhibition of bacterial cell wall synthesis drugs are:A, tetracycline?B, polymyxin?C, penicillin?D, erythromycin?E, E
47、methyl pyrimidine?Standard answer C?2. The drugs that affect the permeability of bacterial cell membranes are:A, amphotericin?B, sulfanilamide?C, cephalosporin?D, erythromycin?E, rifamycin?Standard answer A?3. Drugs that inhibit the synthesis of bacterial DNA are:A, penicillin G?B, sulfamethoxazole?
48、C, he will be sure?D, ciprofloxacin?E, griseofulvin?Standard answer B?4. The drugs that affect the synthesis of bacterial proteins are:A, amoxicillin?B, erythromycin?C, multi - antibiotic?D, ampicillin?E, cefazolin?Standard answer BTwo, multiple-choice questionsEach of the following questions has fi
49、ve alternative answers: A, B, C, D, and E. Please select all the correct answers from the alternative answer.?1, the mechanism of bacterial resistance to antibiotics is:A, the drug can not reach its target siteB and bacterial efflux system were enhanced, and efflux velocity was higher than intra dru
50、g efflux rateC, an enzyme produced by bacteria that inactivate the drug?D and the change of target structure in vivoE and metabolic antagonists have increased in formation,?Standard answer ABCDE2. The basic principle of rational application of antibiotics isA, in strict accordance with indications f
51、or drug selection?B, the appropriate dose and course of treatment?C, select and adjust the dosage according to the patients own conditionShould there be definite indication for D and combination therapy?E should pay attention to the interaction of drugs in combination therapy?Standard answer ABCDEThree, thinkin
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