Sodium-Picosulfate-Standard-Sodium-Picosulphate-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemESodiumPicosulfate(Standard)Cat.No.:HY-B0544RCASNo.:10040-45-6Synonyms:SodiumPicosulphate(Standard)分?式:C??H??NNa?O?S?分?量:481.41作?靶點(diǎn):Others作?通路:Others儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性SodiumPicosulfate(Standard)SodiumPicosulfate的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。SodiumPicosulfate能抑制?和電解質(zhì)的吸收，增加它們的分泌。體外研究SodiumPicosulfate(400,800,1600μg/mL)hasdifferenttoxicitytorabbit,ratandhumanhepatocytes,andrathepatocytesarethebesttolerated[1].體內(nèi)研究SodiumPicosulfate(10mg/kg,dissolvedin0.3%tragacanthinwater,intragastricadministration)hasnosignificanteffectontheproliferationofepithelialcellsintheileumandcolonofrats[2].SodiumPicosulfate(2.5,10mg/kg/day,dissolvedin0.5%tragacanthgum,intragastricadministration)doesnotcausechronicchangesincolonmovementinrats[3].REFERENCES[1].NishikawaJ,etal.Toxicitystudywithsodiumpicosulfateinculturedlivercellsofrabbit,ratandman.Arzneimittelforschung.1981;31(2):321-5.[2].GeboesK,etal.Effectsof'contactlaxatives'onintestinalandcolonicepithelialcellproliferation.Pharmacology.1993Oct;47Suppl1:187-95.[3].FioramontiJ,etal.Invivomotilityofratcolonchronicallypretreatedwithsennosides.Pharmacology.1993Oct;47Suppl1:155-61.[4].RegevA,etal.Comparisonoftwobowelpreparationsforcolonoscopy:sodiumpicosulphatewithmagnesiumcitrateversussulphate-freepolyethyleneglycollavagesolution.AmJGastroenterol.1998Sep;93(9):1478-82.McePdfHeight1/1MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemECaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;0