Scopolin-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEScopolin(Standard)Cat.No.:HY-N0341RCASNo.:531-44-2分?式:C??H??O?分?量:354.31作?靶點(diǎn):Sirtuin作?通路:CellCycle/DNADamage;Epigenetics儲(chǔ)存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Scopolin(Standard)Scopolin的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。Scopolin?種從??芥(Arabidopsis)根中分離出來(lái)的??素。Scopolin通過(guò)激活SIRT1介導(dǎo)的信號(hào)級(jí)聯(lián)反應(yīng)減輕了肝脂變性。REFERENCES[1].SiwinskaJ,etal.IdentificationofQTLsaffectingscopolinandscopoletinbiosynthesisinArabidopsisthaliana.BMCPlantBiol.2014Oct18;14:280.[2].YooA,etal.Scopolinameliorateshigh-fatdietinducedhepaticsteatosisinmice:potentialinvolvementofSIRT1-mediatedsignalingcascadesintheliver.SciRep.2017May22;7(1):2251.[3].RollingerJM,etal.Acetylcholinesteraseinhibitoryactivityofscopolinandscopoletindiscoveredbyvirtualscreeningofnaturalproducts.JMedChem.2004Dec2;47(25):6248-54.[4].PanR,etal.ScopolinisolatedfromErycibeobtusifoliaBenthstemssuppressesadjuvant-inducedratarthritisbyinhibitinginflammationandangiogenesis.IntImmunopharmacol.2009Jul;9(7-8):859-69.[5].LeeSH,etal.ScopoletinandscopolinisolatedfromArtemisiaiwayomogisuppressdifferentiationofosteoclasticmacrophageRAW264.7cellsbyscavengingreactiveoxygenspecies.JNatProd.2013Apr26;76(4):615-20.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax