紀立農(nóng)從高血糖與糖尿病周圍神經(jīng)病變的關系反思和控制策略

從高血糖與糖尿病周圍神經(jīng)病變的關系反思研究和控制策略北京大學人民醫(yī)院

紀立農(nóng)ChinaCardiometabolicRegistries2Nation-wide,prospective,registryseriesdesignedtobetterunderstandclinicaloutcomesof

currenttreatmentofcardiovascularandmetabolicdiseasesinrealworldsettingsOrganizedbyChineseMedicalDoctorAssociationsSupervisedbyCCMRInternationalAdvisoryBoardManagedbyVitalStrategicResearchInstitute

ChinaCardiometabolicRegistries

研究者會議

2011年5月14-15日中國2型糖尿病患者心血管疾病危險因素的縱向隊列研究

中國老年學學會（GSC）主辦

中國醫(yī)師協(xié)會心血管內科醫(yī)師分會(CCCP)協(xié)辦中國醫(yī)師協(xié)會內分泌及代謝科醫(yī)師分會(CEA)協(xié)辦中國心血管代謝病系列研究(CCMR)組織及專家委員會

指導華斯泰生命策略研究所/上海華斯泰醫(yī)學咨詢有限公司(VSRI)執(zhí)行默沙東(中國)有限公司贊助NationwideAssessmentofCardiovascularRiskFactors--BloodPressure,BloodLipid,andBloodGlucoseinChinesePatientswithType2DiabetesLinongJi

PekingUniversityPeople’sHospital

OnbehalfofCCMRAdvisoryBoardJietal.AJM，2013，inpressStudyObjectives–PrimaryPrimaryObjectiveToassessthelevelofcontrolofCVDriskfactors,includingbloodpressure,bloodlipid,andbloodglucose,inoutpatientswithtype2DMin6representativeregionsinChinaandinthreetiersofhospitalsToidentifythegapbetweenrealworlddiabetesmanagementsituationandstandardofcare4Jietal.AJM，2013，inpressStudyObjectives-SecondarySecondaryObjectivesToassesstheproportionofmicrovascularandmacrovasclardiabeticcomplicationsinoutpatientswithtype2DMToassessreal-lifetreatmentpatternsinoutpatientswithtype2DMToassesstheproportionofhypoglyecemiaunderthecurrenttreatmentToassesstheinfluencingfactors(hospitalclassification,regionaldistribution,medicalhistory,educationallevelandothers)onDMtreatmentoutcomes5Jietal.AJM，2013，inpressNon-interventional,observational,cross-sectionaldesignType2diabetesdiagnosedfor6monthsorlongerAmbulatorypatientsfromendocrinology,cardiology,nephrologyclinicsinall3tiersofhospitals(Tier1,2,and3)locatedinall6mainregionsinChinaEstimatedsamplesizewas25,000patientsinordertohavesufficientpowertodetectthedifferenceoftheprimaryassessmentineachregion666StudyDesignTargetedtoenroll25,000patientsJietal.AJM，2013，inpressDistributionofParticipatingHospitals7NumberofsitesineachregionwasproportionaltothepopulationintheregionNationalRegionsTier1Tier2Tier3SUMNorthEast46616North46818East57618NorthWest45514SouthWest59721CentralSouth45716SUM263839103Jietal.AJM，2013，inpressCharacteristicsofstudysubjects8NumberPercentage(%)All25454100.0Age(yr)<651385554.5

>651159945.5GenderMale1195547.0Female1349953.0ResidentUrban2277689.5Rural267810.5BMI(kg/m2)<241061741.7

>241483558.3Meanage=62.6+/-11.9yearsJietal.AJM，2013，inpressDistributionofCVDRiskFactors28%ofthepatientshadT2Donly60%ofthepatientsalsohadHTN(T2D+HTN)About42%ofthepatientsalsohadDYLP(T2D+DYLP)About30%ofthepatientshad“3B”:highbloodglucose,bloodlipid,

andbloodpressure(T2D+HTN+DYLP)9T2D=type2diabetes,HTN=hypertension,DYLP=dyslipidemiaJietal.AJM，2013，inpress

DiabetesDurationandComplications

10Prevalenceofdiabeticcomplicationsisproportionaltodurationofdiabetes(%)DurationofDiabetesJietal.AJM，2013，inpressDiabeticComplicationsandCVD

RiskFactors11(%)Jietal.AJM，2013，inpressCallaghanBC

，etal.CochraneDatabaseSystRev.2012CallaghanBC

，etal.CochraneDatabaseSystRev.2012CallaghanBC

，etal.CochraneDatabaseSystRev.2012CallaghanBC

，etal.CochraneDatabaseSystRev.2012Ca廉ll女a(chǎn)g彎ha底nBC，et菌a沙l.Co貍ch供ra殲neDa牌ta扶ba津se族S幻玉ys花t宇Re廣v.20曠12Ca拼ll聚ag腰ha咬nBC，et稿a驕l.Co發(fā)ch鼻ra透neDa括ta兄ba伶se緞S恥ys府t吃Re必v.20溉12Ca蟻ll布ag盼ha路nBC，et漿a鞭l.Co腰ch蜘ra巾neDa伍ta池ba方se主S破ys誦t位Re擱v.20芹12Ca爸ll冒ag陽ha甚nBC，et是a兇l.Co饒ch貢ra織neDa語ta掙ba圍se殖S刃ys歪t(yī)跳Re墓v.20譯12Ca貼ll優(yōu)ag破ha不nBC，et雅a烤l.Co苦ch遲ra亭neDa褲ta至ba霧se漿S伙ys侍t盒Re蹈v.20杏12Ca減ll與ag托ha澇nBC，et悔a煉l.Co盈ch席ra笨neDa償ta沒ba打se終S茂ys觀t開Re刷v.20辰12Ca余l(xiāng)l爹ag補ha使nBC，et境a持l.Co欣ch哪ra弟neDa粘ta扭ba樹se撒S抽ys嚼t泄Re超v.20旦12Ca壯ll冤ag欲ha萌nBC，et是a宗l.Co功ch夏ra晉neDa倒ta關ba績se種S墨ys紡t餐Re表v.20燒12G?芒de朵,桿P.沈e涂t.孝a干l.職N怪E計ng市l(wèi)疑JMe鈔d脾20巷03師;3刪48資:3言83點-3腹93Re與su傭lt牌s兼fr板om駁P逼at籮ie杠nt濤s雄wi獵th羊T鵲yp勿e2Di餡ab煮et縫es塑-ST避EN柿O2Di攀ab松et盛ic性N壞eu母ro差pa救th束y怎in間T自yp梨e寨2畢Pa閥ti華en蓋tsPa債ti絮en州tsca皂n懂be歪c工la林ss銷if體ie跌d雷in斃to2gr備ou潔psba狹se名d典onmy惕el概in肅at漏ed鎖f寨ib距er芒d涼en康si百tylo肥ssov途er迷5司2搬we恨ek確sMF剛DSu姿ra鵝lne丸rv禾ebi禽op老si耕es村o亂f周42懷7pa攜ti嫩en攜tsTRIGLYCERIDESWi賀gg保in構e立t嬸al匙,賴Di光ab離et西es首,盒20淘09G?