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2021-2022年四川省雅安市公共英語五級(jí)(筆試)模擬考試(含答案)學(xué)校:________班級(jí):________姓名:________考號(hào):________
一、1.ListeningComprehension(15題)1.聽力原文:Normallyastudentmustparticipateinacertainnumberofcoursesinordertograduate,andeachcoursewhichheattendsgiveshimacreditwhichhemaycounttowardsadegree.InmanyAmericanuniversitiesthetotalworkforadegreeismadeupofthirty-sixcourseseachlastingforonesemester.Atypicalcourseconsistsofthreeclassesperweekforfifteenweeks;whileattendingauniversityastudentwillprobablyattendfourorfivecoursesduringeachsemester.Normallyastudentwouldexpecttotakefouryearsattendingtwosemesterseachyear.Itispossibletospreadtheperiodofworkforthedegreeoveralongerperiod.Itisalsopossibleforastudenttomovebetweenoneuniversityandanotherduringhisdegreecourse,thoughthisisnotinfactdoneasaregularpractice.
Foreverycoursethathefollowsastudentisgivenagrade.whichisrecorded,andtherecordisavailableforthestudenttoshowtoprospectiveemployers.Allthisimposesaconstantpressureandstrainofwork,butinspiteofthissomestudentsstillfindtimeforgreatactivityinstudentaffairs.Electionstopositionsinstudentorganizationsarousemuchenthusiasm.Theeffectiveworkofmaintainingdisciplineisusuallyperformedbystudentswhoadvisetheacademicauthorities.Anystudentwhoisthoughttohavebrokentherules,forexample,bycheatinghastoappearbeforeastudentcourt.Withtheenormousnumbersofstudents,theoperationofthesystemdoesincludeacertainamountofactivity.Astudentwhohasheldoneofthesepositionsofauthorityismuchrespectedanditwillbeofbenefittohimlaterinhiscareer.
What'sthemainobjectiveofastudentwhoattendsacertainnumberofcourses?
A.Tograduateandobtainadegree.
B.Tolearnsomethingheisinterestedin.
C.Toavoidworking.
D.Toobeyhisparents'order.
2.PartA
Directions:Youwillhearatalk.Asyoulisten,answerQuestions1-10bycirclingTRUEorFALSE.YouwillhearthetalkONLYONCE.Younowhave1minutetoreadQuestions1-10.
聽力原文:Thereareseveralplacesintheworldthatarefamousforpeoplewholiveforaverylongtime.Thesesplacesareusuallymountainousareas,farawayfrommodemcities.Doctors,scientistsandpublichealthexpertsoftentraveltotheseregionstosolveamysteriouslonghealthylife;theexpertshopetobringtothemodemworldthesecretsoflongevity.
HunzaishighintheHymalayanMountainsofAsia.There,manypeopleoveronehundredyearsofagearestillinphysicalhealth.Menofninetyarenewfathers.a(chǎn)ndwomenoffiftystillhavebabies.Whatarethereasonsforthisgoodhealth?ScientistsbelievethatthepeopleofHunzahavethesethreebenefits:first,physicalwork,usuallyinthefieldsorwithanimals;second,ahealthenvironmentwithcleanairandwater:andwhat'smore,asimplediethighinvitaminsandnutritionbutlowinfat,cholesterol,sugarandchemicals.
PeopleintheCaucasusMountaininRussiaarealsofamousfortheirlongevity.Inthisarea,thereareamazingexamplesofverylong-livedpeople.Birthrecordsarenotusuallyavailable.butawomancalledTsurbaprobablyliveduntilage160;amancalledShiraliprobablyliveduntil168.Hiswidowwas120yearsold.Ingeneral,peoplenotonlylivealongtime,buttheyalsolivewell.Theyarealmostneversick,andwhentheydie,theyhavenotonlytheirownteethbutalsoafullheadofhairandgoodeyesight.
Vilcabamba,Ecuador,isanotherareafamousforthelongevityofitshabitants.Thisregion—likeHunzaandtheCaucasus—isalsoinhighmountains.farawayfromcities.InVilcabamba.too.thereisverylittledisease.Onereasonforthegoodhealthofthepeoplemightbetheclean,beautifulenvironment:thetemperatureisabout70Fahrenheitallyearlong;thewindalwayscomesfromthesamedirection;andtheregionisrichinflowers,fruits,vegetablesandwildlife.
Insomeways,thedietsofthehabitantsinthethreeregionsarequitedifferent.Hunzukutseatmainlyrawvegetables,fruit(especiallyapricots),andchapattis—akindofpancake;theyeatmeatonlyafewtimesayear.TheCaucasiandietconsistsmainlyofmilk,cheese,vegetables,fruitandmeat;mostpeopletheredrinkthelocalredwinedaily.InVilcabamba,peopleeatasmallamountofmeateachweek,batthedietconsistslargelyofgrain,corns,beans,potatoesandfruit.
ExpertsfindonesurprisingfactinthemountainsofEcuador.Mostpeoplethere,eventheveryold,consumealotofcoffee,drinkalargeamountofalcohol,andsmokefortytosixtycigarettesdaily.
However,thedietsaresimilarintwogeneralways:first,thefruitsandvegetablesthattheinhabitantsofthethreeareaseatareallnatural;thatis,theycontainnochemicalsandsecond,thepeopleconsumefewercaloriesthanpeopledointheotherpartsoftheworld.AtypicalNorthAmericantakesinallaverageof3,300calorieseveryday;atypicalinhabitantofthesemountainousareasbetween1,700and2,000calories.
Inhabitantsinthethreeregionshavemoreincommoncalories,naturalfood,theirmountainsandtheirdistancefrommodemcities.becausethesepeopleliveincountrysideandaremostlyfarmers,theirlivesarephysicallyhard.Thus,theydonotneedtogotohealthclubsbecausetheygetalotofexerciseintheirdailywork.Inaddition,although,theirlivesarehard,thepeopledonotseemtohavetheworriesofcitypeople.Theirlivesarequiet.Consequently,someexpertsbelievethatphysicalexerciseandfreedomfromworrymightbethetwomostimportantsecretsoflongevity.
Somemodemcitiesareusuallyfamousforpeoplewholiveaverylongtime.
A.RightB.Wrong
3.PartA
Directions:Youwillhearatalk.Asyoulisten,answerQuestions1-10bycirclingTRUEorFALSE.YouwillhearthetalkONLYONCE.Younowhave1minutetoreadQuestions1-10.
聽力原文:W:Comein,please.
M:Goodmorning,Dr.Wilson.
W:Goodmorning,Wang.Hownicetomeetyouagain.Takeaseat…whydon'tyou,please.Whendidyougettotheuniversity?
M:Iarrivedyesterday.
W:Well…areyoulivinginthecollege?
M:No,IamwithanEnglishfamily…actually…becauseIwanttoimprovemyspeaking.
W:Oh,fine.Right,didyoutakealanguageproficiencytestbeforeyoucame?
M:Yes.Uhh…myOverallBandis6,but…unfortunatelymyspeakingscoreisonly5.
W:OK,youknow,hereinthisuniversity,youhavetotakeourownEnglishtestbeforeyouattendanylectures.So,firstofau.whatwe'vegottodois,wehavetomakeanarrangementforthetestdate.Umm…willtomorrowbeallfightforyou?
M:Yeah,Ihavetimetomorrowmorning.
W:Good,then.Tomorrowatten.Idon'tthinkthetestwillbeanyproblemforyou.Now,let'smakesureyoumakegooduseofyourtimehere.Let'sputitlikethis.Whatexactlydoyouwanttoaccomplishinthenext12months?
M:I'minterestedincomputerlanguagetranslation,Imean,fromEnglishtoChineseandChinesetoEnglish.I'lltry,ifpossible,toproducesoftwareoradevicewhichcanserveasaninterpreter.
W:Yes,couldyoubeabitmorespecificabout…er…thedevice?
M:Forinstance,whenyoutalktothedeviceinEnglishitwilltranslateyourwordsintoChineseandviceversa.
W:Uhuh…doyoumeanit'llbeascompetentas…er…ahumaninterpreter?
M:Yes…well,I'llletitdealwithgeneralsituations,atleast.
W:Fascinating…andhowbigwillthedeviceitselfbe,doyouthink?
M:Thesizeofacigarettepack,Ithink.Sopeoplecanputitintheirpocket.
W:Really?Well,thatcouldbeaPh.Dproject.Tellmewhatyouhavedonesofar.
M:Inmyfouryearsofundergraduatestudy,Istudiedelectronics,advancedmathematics,hardwaredesigning,somecomputerlanguagesandprogramwriting.
W:Yes,buthaveyoudoneanypracticaljobs?Imean,haveyouwrittenanyprogramsforpracticaluse?
M:IhadbeeninvolvedinaprojectforCADinashipyard.
W:Computeraideddesign.Thatwasprobablyagoodexperience,but,unfortunately,itmaynothelpyourpresentprojectmuch.AreyoufamiliarwiththeC-language?
M:No.
W:Uhuh…thephoneticprocessingsystem,doyouknowhowsuchasystemworks?
M:Whatdoyoumeanby“phoneticprocessingsystem”?
W:Well,youknow,Englishisspokenbydifferentpeoplewithdifferentaccents.YourEnglishaccentisdifferentfrommine,andofcoursemineisnotthesameasmycolleagues.SoasIseeit.yourdevicewouldhavetobeabletorecogniseandunderstanddifferentaccents.
M:Oh,Isee.IthinkIcanlearntheC-languageandthephoneticprocessingsystemhere.
W:Well,that'sprobablytrue,butyou'vegotonlytwelvemonthsandyouwantadegree,don'tyou?
M:Yes.
W:OK,sothere'retwowaysofstudyingforadegreehere.Youeithertakesixcourses,passtheirexamsandhaveyourdissertationacceptedortheotherwayisyoudosomeresearchworkandsubmityourprojectreport.
M:IthinkI'lltakethesecondway.
W:Fine,butareyousureyoucallfinishyourprojectintwelvemonths?
M:Idon'tknow.butIcanworktwelvehoursperdayandsevendaysperweek.
W:Well,I'dsuggestyouspendsometimeinourlibrary,tryingtofindoutwhatotherstudentshavedonebeforeandperhapsreconsideryourownproject,tosomeextent.Youmightnarrowyourresearcharea,concentratingonsolvingoneortwomajorproblems.And,it'dbeagoodideatotalktoyourcolleaguesinthelab,first.Anyway,I'msurewecanworkoutsomethinggood.ShallIseey
A.RightB.Wrong
4.Accordingtothefigureoftheacademicyear1995/96,wheredothelargestnumberofforeignstudentscomefrom?
5.Thesuccessofchainschoolsistosomeextentbecauseofthemarketingandadvertising.
A.TrueB.Fasle
6.PartC
Directions:Youwillhearatalk.Asyoulisten,answerthequestionsorcompletethenotesinyourtestbookletforQuestions21-30bywritingNOTMORETHANTHREEwordsinthespaceprovidedontheright.YouwillhearthetalkTWICE.
Younowhave1minutetoreadQuestions21-30.
聽力原文:ForthoseofyouwhoareeitheralreadystudyingintheUnitedStatesorplanningtooneday,itmightbeinterestingtoknowsomethingabouttheforeignstudentpopulationintheUnitedStates.Fortheacademicyear1995/96therewasasumofapproximately344,000foreignstudentsstudyingintheUnitedStates.Thisfigureof344000mayseemlikeaverylargenumberuntilyoucompareitwiththetotalpopulationof241,000,000.Theforeignstudentpopulationhasbeengrowingforanumberofyearsandisstillgrowing,buttherateofincreasehasdroppedsharplyduringthe1990s.Duringthe1980s,thepopulationgrewquiterapidly.Forexample,between1985and1990,theaverageyearlyincreasewas12.5%.However,thepictureinthe1990sisquitedifferent.Therateofincreasehasdeclinedquitenoticeably.Infact,therateofincreasebetween1994/95and1995/96wasonly0.5%,orone-halfofonepercent.Althoughtheoverallrateofincreasehasdroppedtoonly0.5%,thenumberofstudentsfromsomepartsoftheworldisincreasingwhilethenumberofstudentsfromotherareasisdecreasing.Forexample,duringthissameperiod,thatisbetweentheacademicyears1994/95and1995/96,therewasadecreaseinthenumberofstudentsfromtheMiddleEast,whilethenumberofstudentsfromSouthandEastAsiaincreased.Thesechangesinthenumberofstudentscomingfromdifferentpartsoftheworldnodoubtreflectedchangingeconomicandpoliticalsituations.I'msureyouareawareofmanyofthesechanges,andperhapsyoucandiscussthematournextmeeting.Fortodaylet'sconfineourtalktofirst,adiscussionoftheoriginofthesestudents,or,inotherwords,wheretheycamefromsecond,thekindsofstudiestheypursue;and,finally,theacademiclevelstheyarefoundin.Ifwehavealittletimeleft,wemightquicklytalkaboutinwhichgeographicareasmostofthemgotoschool.
Let'sdiscusstheoriginsoftheforeignstudentpopulationintheUnitedStatesfortheacademicyear1995/96.Let'sdiscussitinorderfromthoseareassendingthemoststudentstothoseareassendingthefeweststudents.IfwelookatthefiguresprovidedbytheannualcensusofforeignstudentsintheUnitedStatesfortheyear1995/96,weseethatmostoftheforeignstudentsstudyingintheUnitedStatesduringthisyearwerefromSouthandEastAsia.Thisisaratherlargegeographicalareawhichincludessuchconu-triesasChina,Korea,Pakistan,India,Malaysia,andIndonesia.Thetotalnumberofstudentsfromthisarea,SouthandEastAsiawas156,830.Inotherwords,roughly2outofevery5foreignstudentscomefromSouthandEastAsia.Almost24000ofthistotalwerefromChina.Malaysiawasclosebehindwithjustalittleover23000students.ThenextlargestnumberofstudentscamefromtheMiddleEast.ThenumberofstudentsfromtheMiddleEastcametoaboutone-thirdthenumberfromSouthandEastAsia.ThefourthlargestnumbercamefromSouthAmerica.NextcameEurope,Africa,NorthAmerica,andOceania.Let'srecapitulatewhatwe'vesaid.ThelargestnumberofstudentsstudyingintheUnitedStatesduringtheacademicyear1995/96werefromSouthandEastAsia,followedbytheMiddleEast,SouthAmerica,Europe,Africa,NorthAmerica,andOceania.
Whatfieldsaretheselargenumbersofforeignstudentsstudyingin?Itprobablywon'tsurpriseyouthatthelargestnumberareinthefieldofengineering.Infact,21.7%ofthetotalnumberarestudyingengineering.Businessandmanagementisclosebehind,however,withatotalof18.9%.Thethirdmostpopularfieldw
7.WhatdidFranklinsetupbetweenthenorthernandsoutherncolonies?
8.MDdecidescompany'spoliciesandcarriesthemout.
A.TrueB.Fasle
9.HowmanypsychologicaltypesofpeoplearethereaccordingtoJung'sideas?
10.Ifaconsumerwantsaquicksettlementoftheproblem,whomisitbettertocomplainto?
A.Ashopassistant.
B.Thestoremanager.
C.Themanufacturer.
D.Apublicorganization.
11.Sugarincoldsweetdrinksslowstheliquidfromgettingintotheblood-stream.
A.RightB.Wrong
12.The"feltimage"ismuchmoreimportantbecauseithelpsyoutobemoreconfident.
A.TrueB.Fasle
13.Whathasgivenwomenanindependenceinformingafamily?
14.Whichsubjectdoesthestudentsayshewasgoodat?
A.Computerprogramming.
B.Artanddesign.
C.Electronics.
D.Mathematics.
15.MDhassixdepartmentalmanagersatthemoment.
A.RightB.Wrong
二、2.UseofEnglish(10題)16.
【C11】
17.(42)
18.(36)
19.
【C14】
20.(50)
21.(45)
22.
【C6】
23.
【C7】
24.
【C17】
25.(41)
三、3.ReadingComprehension(15題)26.PartB
Directions:Inthefollowingarticlesomeparagraphshavebeenremoved.ForQuestions66-70,choosethemostsuitableparagraphfromthelistA-Ftofitintoeachofthenumberedgaps.Thereisoneparagraphwhichdoesnotfitinanyofthegaps.MarkyouranswersonANSWERSHEET1.
Thepressisconstantlyremindingusthatthedramaticincreaseintheageofourpopulationoverthenext30orsoyearswillcausenationalhealthcaresystemstocollapse,economiestocrumpleunderthestrainofpensiondemandsanddisintegratingfamiliestobuckleunderincreasingcarecommitments.YetresearchatOxfordisbeginningtoexposesomeofthewidespreadmythsthatunderliethisrhetoric.Demographicageingisundoubtedlyareality.Lifeexpectancyindevelopedcountrieshasrisencontinuouslyoverthepastcentury,increasingthepercentageofthoseovertheageof60relativetothoseundertheageof15.By2030halfthepopulationofWesternEuropewillbeovertheageof50,withapredictedaveragelifeexpectancyofafurther40years.Bythen,aquarterofthepopulationwillbeover65andby2050theUK'scurrentnumberof10,000centenariansarepredictedtohavereachedaquarterofamillion.SomedemographershaveevensuggestedthathalfofallbabygirlsbornintheWesttodaywilllivetoseethenextcentury.
66.______
Indeed,ifthiscouldbeachievedthroughouttheworld,itwouldsurelycountasthesuccessofcivilization,forthenwewouldalsohaveconqueredthekillersofpoverty,disease,famineandwar.
Decreasingmortalityrates,increasinglongevityanddecliningfertilitymeansmallerpercentagesofyoungpeoplewithinpopulations.Overthepast20yearslifeexpectancyatbirthintheUKhasrisenbyfouryearsformen(to75)andthreeyearsforwomen(to80).MeanwhilefertilityratesacrossEuropehavedeclinedmoreorlesscontinuouslyoverthepast40yearsandremainwellbelowthelevelsrequiredforEuropeanpopulationstobeabletoreplacethemselveswithoutsubstantiveimmigration.Butagain,ratherthanseeingthisasadoomandgloomscenario,weneedtoexplorethepositiveaspectsofthesedemographics.Thenext50yearsshouldprovideuswithanopportunitytoenjoythemanyadvantagesofasocietywithamaturepopulationstructure.
67.______
ThefirstoftheseisthecurrentpoliticalrhetoricwhichclaimsthathealthservicesacrosstheWesternworldarecollapsingunderthestrainofdemographicageing.
68.______
Thesecondmythistheviewthattheratioofworkerstonon-workerswillbecomesoacutethatWesterneconomieswillcollapse,compoundedbyamassivegrowthinpensiondebt.Whilethereareundoubtedconcernsovercurrentpensionshortfalls,itisalsoclearthatworkingliveswillthemselveschangeoverthenextfewdecades,withapredictedincreaseinflexibleandpart-timeworkandtheprobableextensionofworkinglifeuntiltheageof70.Indeed,wehavetorecognizethatwecannotexpecttoretireattheageof50andthenbeabletosupportourselvesforanother40orsoyears.Neitherasolidpensionschemenorsavingscancarrypeoplethatlong.
69.______
Afurthermythisthatwewillallliveinloose,multigenerationalfamilies,experiencingincreasedemotionaldistancingfromourkin.Evidencefromavarietyofstudiesacrossthedevelopedworldsuggeststhat,ifanything,themodernfamilyisactuallybecomingmoreclose-knit.WorkcarriedoutbytheOxfordInstituteinScandinaviaandinaPan-EuropeanFamilyCareStudy,forexample,showsthatdespitedieinfluenceofthewelfarestate,overthepast10years,peoplehavecometovaluefamilyrelationshipsmorethanpreviously.
70.______
Inthedevelopedworld,therefore,wecanseeactualbenefitsfrompopulationageing:abetterbalancebetweenagegroups,matureandlessvolatiles
27.
Privacystandardsmadebyindividualstatesareineffectivebecause______.
A.thestandardsofdifferentstatescontradicteachother
B.onlinecommunicationisnotrestrictedtoanystate
C.thesestandardsignorethefederallawonthematter
D.thesestandardsareonlyapplicabletoregionalwebsites
28.(74)
29.(75)
30.
WhatisNOTtrueabouttheeightgirls?
A.Theyareallbetween12and17.
B.Theyhavetriedavarietyofmeasures.
C.Theyattendasuicidesquad.
D.Alltheirattemptstocommitsuicidearevital.
31.(69)
32.ShortagesoffluvaccinearenothingnewinAmerica,butthisyear'sisawhopper.Untillastweek,itappearedthat100millionAmericanswouldhaveaccesstoflushotsthisfall.ThenBritishauthorities,concernedaboutquality-controlproblemsataproductionplantinLiverpool,barredallfurthershipmentsbytheChironCorp.Overnight,theU.S.vaccinesupplydwindledbynearlyhalfandfederalhealthofficialsfoundthemselvesmakinganunusualplea.Insteadofbeseechingusalltogetvaccinated,they'renowurgingmosthealthypeoplebetweentheagesof2and64notto."Thisreemphasizesthefragilityofourvaccinesupply,"saysDr.MartinMyersoftheNationalNetworkforImmunizationInformation,"andthelackofredundancyinoursystem."
Whyissuchabasichealthservicesoeasilyknockedout?Mainlybecauseprivatecompanieshavehadlittleincentivetopursueit.Tocreateasingledoseoffluvaccine,amanufacturerhastogrowlivevirusina2-week-oldfertilizedchickenegg,thencracktheegg,harvestthevirusandextracttheproteinsusedtoprovokeanimmunere-sponse.Profitmarginsarenarrow,demandisfickleand,becauseeachyear'sfluvirusisdifferent,anyleftovervaccinegoestowaste.Asaresult,theUnitedStatesnowhasonlytwomajorsuppliers(ChironandAventisPasteur)—andwhenoneofthemrunsintotrouble,thereisn'tmuchtheothercandoaboutit."Avaccinemakercan'tjustcallupandorder40millionmorefertilizedeggs,"saysManonCox,ofConnecticut-basedProteinSciencesCorp."There'sawholeindustrythat'sscheduledtoproduceacertainnumberofeggsatacertaintime."
Sleekertechnologiesarenowintheworks,andexpertsarehopingthatthisyear'sfiascowillspeedthepaceofinnovation.Themainchallengeistoshiftproductionfromeggsintocellcultures—amediumalreadyusedtomakemostothervaccines.Fluvaccinesareharderthanmosttoproducethisway,butseveralbiotechcompaniesarenowpursuingthisstrategy,andoneculture-basedproduct(SolvayPharmaceuticals'Invivac)hasbeenclearedformarketinginEurope.
ForAmericans,theimmediatechallengeistomakethemostofalimitedsupply.Thegovernmentestimatesthat95millionpeoplestillqualifyforshotsunderthevoluntaryrestrictionsannouncedlastweek.That'snearlytwicethenumberofdosesthatclinicswillhaveonhand,butonly60millionAmericansseekoutshotsinanormalyear.Infact,manyexpertsarehopingtheshortagewillserveasanawarenesscampaign—encouragingthepeoplewhoreallyneedaflushottogetone.
Shortagesoffluevaccineshowthat______.
A.Americareliestoomuchonforeignsuppliers
B.thedemandoffluevaccinesishighthisyear
C.qualityproblemisaseriousprobleminfluvaccineproduction
D.thesupplyoffluvaccinesisratherweakandAmericahasnoback-upmeasurestomakeitup
33.(78)
34.
Thevalueofcompetitionworksagainstthespiritofnationalcooperationinthat______.
A.itmakespeoplenotbelieveinthegovernment
B.itcausespeopletosuspectbutnottotrusteachother
C.itmakespeopleevenunabletocooperatewellonlocallevels
D.itencouragespeopletogainsuccessthroughindividualhardwork
35.At18,AshanthiDeSilvaofsuburbanClevelandisalivingsymbolofoneofthegreatintellectualachievementsofthe20thcentury.Bornwithanextremelyrareandusuallyfataldisorderthatleftherwithoutafunctioningimmunesystem(the"bubble-boydisease",namedafteranearliervictimwhowaskeptaliveforyearsinasterileplastictent),shewastreatedbeginningin1990witharevolutionarynewtherapythatsoughttocorrectthedefectatitsverysource,inthegenesofherwhitebloodcells.Itworked.Althoughherlastgene-therapytreatmentwasin1992,sheiscompletelyhealthywithnormalimmunefunction,accordingtooneofthedoctorswhotreatedher,W.FrenchAndersonoftheUniversityofSouthernCalifornia.Researchershavelongdreamedoftreatingdiseasesfromhemophiliatocancerbyreplacingmutantgeneswithnormalones.Andthedreamingmaycontinuefordecadesmore."Therewillbeagene-basedtreatmentforessentiallyeverydisease,"Andersonsays,"within50years."
It'snotentirelyclearwhymedicinehasbeensoslowtobuildonAnderson'searlysuccess.TheNationalInstitutesofHealthbudgetofficeestimatesitwillspend$432millionongene-therapyresearchin2005,andthereisnoshortageofpromisingleads.Thetherapeuticgenesareusuallydeliveredthroughvirusesthatdon'tcausehumandisease."ThevirusissortoflikeaTrojanhorse,"saysRonaldCrystalofNewYorkPresbyterian/WeillCornellMedicalCollege."Thecargoisthegene."
AttheUniversityofPennsylvania'sAbramsonCancerCenter,immunologistCarlJunerecentlytreatedHIVpatientswithageneintendedtohelptheircellsresisttheinfection.AtCornellUniversity,researchersarepursuinggene-basedtherapiesforParkinson'sdiseaseandararehereditarydisorderthatdestroyschildren'sbraincells.AtStanfordUniversityandtheChildren'sHospitalofPhiladelphia,researchersaretryingtofigureouthowtohelppatientswithhemophiliawhotodaymustinjectthemselveswithexpensiveclottingdrugsforlife.Animalexperimentshaveshowngreatpromise.
Butsomehow,thingsgetlostinthetranslationfromlaboratorytopatient.Inhumantrialsofthehemophiliatreatment,patientsshowaresponseatfirst,butitfadesovertime.Andthefieldhasstillnotrecoveredfromthesetbackitsufferedin1999,whenJesseGelsinger,an18-year-oldwithararemetabolicdisorder,diedafterreceivinganexperimentalgenetherapyattheUniversityofPennsylvania.Someexpertsworrythatthefieldwillbetarnishedfurtherifthenextpeopletobenefitarenotpatientsbutathletesseekinganedge.Thissummer,researchersattheSalkInstituteinSanDiegosaidtheyhadcreateda"marathonmouse"byimplantingagenethatenhancesrunningability;already,officialsattheWorldAnti-DopingAgencyarepreparingtotestathletesforsignsof"genedoping".Buttheprincipleisthesame,whetheryou'retryingtohelpahealthyrunnerrunfasterorallowamuscular-dystro-phypatienttowalk."Everybodyrecognizesthatgenetherapyisaverygoodidea,"saysCrystal."Andeventuallyit'sgoingtowork."
ThecaseofAshanthiDesilvaismentionedinthetextto
A.showthepromiseofgene-therapy
B.giveanexampleofmodemtreatmentforfataldiseases
C.introducetheachievementofAndersonandhisteam
D.explainhowgene-basedtreatmentworks
36.
Privatecompanieshavelittleinterestinproducingfluvaccinesbecauseof______.
A.complicatedprocess,highcost,lowprofitandhighrisk
B.shortagesoffertilizedchickeneggs
C.difficultyingrowinglivevirus
D.fastchangingoffluvirus
37.Themanbehindthisnotion,JackMaple,isadandywhoaffectsdarkglasses,homburgs(翹邊帽)andtwo-toeshoes;yethehasbecomesomethingofalegendinAmerica'spolicedepartments.Forsomeyears,startinginNewYorkandmovingontohigh-crimespotssuchasNewOrleansandPhiladelphia,heandhisbusinesspartner,JohnLiederhavemarketedatwo-tiersystemforcuttingcrime.
First,policedepartmentshavetosortthemselvesout:rootoutcorruption,streamlinetheirbureaucracy,andmakemorecontactwiththepublic.Second,theyhavetoadoptacomputersystemcalledComstatwhichhelpsthemtoanalyzestatisticsofallmajorcrimes.Theseareconstantlykeyedintothecomputer,whichthendisplayswhereandwhentheyhaveoccurredonacolor-codedmap,enabl
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