Tuberculosis-inhibitor-3-DataSheet-生命科學(xué)試劑-MedChemExpress

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemETuberculosisinhibitor3Cat.No.:HY-114147CASNo.:2219325-28-5分?式:C??H??F?N?O?S分?量:524.48作?靶點(diǎn):Bacterial作?通路:Anti-infection儲(chǔ)存?式:Powder-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性數(shù)據(jù)體外實(shí)驗(yàn)DMSO:27.5mg/mL(52.43mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制備儲(chǔ)備液1mM1.9067mL9.5333mL19.0665mL5mM0.3813mL1.9067mL3.8133mL10mM0.1907mL0.9533mL1.9067mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度選擇合適的溶劑配制儲(chǔ)備液；?旦配成溶液，請(qǐng)分裝保存，避免反復(fù)凍融造成的產(chǎn)品失效。儲(chǔ)備液的保存?式和期限：-80°C,6months;-20°C,1month。-80°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?，-20°C儲(chǔ)存時(shí)，請(qǐng)?jiān)?個(gè)?內(nèi)使?。BIOLOGICALACTIVITY?物活性Tuberculosisinhibitor3(compound2i)對(duì)敏感性，和耐性的MTB株均具有良好的抗結(jié)核活性。Tuberculosisinhibitor3(compound2i)顯?出良好的藥代活性和?服?物利?度。體外研究Tuberculosisinhibitor3(compound2i,50mg/kg)showsacceptablePKpropertieswiththeAUCof2489h?ng/mL)is.TheTmaxofTuberculosisinhibitor3is0.25h[1].1/2MasterofBioactiveMolecules—您?邊的抑制劑?師www.MedChemEREFERENCES[1].KaiLv,etal.Design,synthesisandantitubercularevaluationofbenzothiazinonescontainingapiperidinemoiety.EurJMedChem.2018May10;151:1-8.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:021-537003