細(xì)胞生物學(xué)_05物質(zhì)的跨膜運輸重要參考

1、LOWTransport Passive Simple diffusionOsmosisActivetransportl不需要能量，自發(fā)發(fā)生不需要能量，自發(fā)發(fā)生l動力來自濃度差別，不需要外界幫助，順動力來自濃度差別，不需要外界幫助，順濃度剃度運輸濃度剃度運輸5. 1 Passive transportl需要能量需要能量l低濃度運輸導(dǎo)高濃度，逆濃度低濃度運輸導(dǎo)高濃度，逆濃度l轉(zhuǎn)運蛋白參與轉(zhuǎn)運蛋白參與Active transport5.1.1 DiffusionIf a concentration gradient exists, there will be a net flow of mater

2、ial across the membrane高高低低Hypotonic低滲低滲Hypertonic高滲高滲isotonichypotonichypertonic等滲等滲5.1.3 Facilitated Diffusion協(xié)助擴散協(xié)助擴散Na+glucoseMembrane Trans. Protein A Carrier protein B Channel protein Carrier protein change shape let material transportChannelTypes of channel protein or ion channel Brief summar

3、y of passive transport +Charged particle cloaked with water molecules, can not get throughNa+Cl-K+H+Large molecules, also cloaked with water molecules, can not get throughNucleotidesAmino acidsSugarsThree ways of driving active transport. Active transporthttp:/www.cat.cc.md.us/courses/bio141/lecguid

4、e/unit1/eustruct/sppump.htmlQuestion: Compare with glucose transport by facilitated transport and active transport ? Aniport 運輸小泡與靶膜融合運輸小泡與靶膜融合 Endocytic vesicle forming mechanism 大部分回到質(zhì)膜重新利用大部分回到質(zhì)膜重新利用少數(shù)進入溶酶體，受體下降調(diào)節(jié)少數(shù)進入溶酶體，受體下降調(diào)節(jié) (receptor down regulation) 少數(shù)運輸?shù)劫|(zhì)膜不同區(qū)域少數(shù)運輸?shù)劫|(zhì)膜不同區(qū)域6. 轉(zhuǎn)胞吞作用：受體和配體不作任何處理，轉(zhuǎn)胞吞作用：受體和配體不作任何處理，內(nèi)吞物從極性細(xì)胞一側(cè)轉(zhuǎn)到相反的方向。內(nèi)吞物從極性細(xì)胞一側(cè)轉(zhuǎn)到相反的方向。母乳喂養(yǎng)之所以可以給寶寶抗體正是轉(zhuǎn)胞母乳喂養(yǎng)之所以可以給寶寶抗體正是轉(zhuǎn)胞吞作用原理實現(xiàn)的。吞作用原理實現(xiàn)的