1-1-Ethylidenebis-L-tryptophan-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemE1,1′-Ethylidenebis[L-tryptophan]Cat.No.:HY-W585843CASNo.:132685-02-0分?式:C??H??N?O?分?量:434.49作?靶點(diǎn):InterleukinRelated作?通路:Immunology/Inflammation儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性1,1′-Ethylidenebis[L-tryptophan]?種L-?氨酸合成過程中的雜質(zhì)。1,1′-Ethylidenebis[L-tryptophan]可促進(jìn)嗜酸性??病細(xì)胞的增殖、誘導(dǎo)嗜酸性粒細(xì)胞釋放嗜酸性粒蛋?，并刺激T細(xì)胞產(chǎn)?IL-5。1,1′-Ethylidenebis[L-tryptophan](40μg/kg)可在??中可引起筋膜增、肥?細(xì)胞浸潤及脂組織和?下肌?的纖維化。1,1′-Ethylidenebis[L-tryptophan]可?于免疫學(xué)和炎癥領(lǐng)域研究[1][2][3]。REFERENCES[1].YamaokaKA,etal.1,1'-Ethylidenebis(tryptophan)(PeakE)inducesfunctionalactivationofhumaneosinophilsandinterleukin5productionfromTlymphocytes:associationofeosinophilia-myalgiasyndromewithaL-tryptophancontaminant.JClinImmunol.1994Jan;14(1):50-60.[2].TrucksessMW.SeparationandisolationoftraceimpuritiesinL-tryptophanbyhigh-performanceliquidchromatography.JChromatogr.1993Feb5;630(1-2):147-50.[3].LoveLA,etal.PathologicalandimmunologicaleffectsofingestingL-tryptophanand1,1'-ethylidenebis(L-tryptophan)inLewisrats.JClinInvest.1993Mar;91(3):804-11.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:021-537