Chlorpheniramine-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors ? ScreeningLibraries ? Proteinswww.MedChemEChlorpheniramine(Standard)Cat.No.:HY-B0286RCASNo.:132-22-9分子式:C??H??ClN?分子量:274.79作用靶點(diǎn):HistamineReceptor作用通路:GPCR/GProtein;Immunology/Inflammation;NeuronalSignaling儲(chǔ)存方式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY生物活性Chlorpheniramine(Standard)是Chlorpheniramine的分析標(biāo)準(zhǔn)品。本產(chǎn)品用于研究及分析應(yīng)用。Chlorpheniramine是過(guò)敏性疾病常用的H1型抗組胺試劑。IC50&TargetIC50:43μMinBV2microglialcellsREFERENCESJiwonKim,etal.Inhibitoryeffectsofantihistamines,diphenhydramineandchlorpheniramine,onprotoncurrentsinBV2microglialcells.EurJPharmacol.2017Mar5;798:122-128.Kyung-JinJung,etal.EnhancementofBcellandmonocytepopulationsinratsexposedtochlorpheniramine.ArchPharmRes.2012Dec;35(12):2183-9.Takano,N.,I.Arai,andM.Kurachi,AnalysisofthespontaneousscratchingbehaviorbyNC/Ngamice:apossibleapproachtoevaluateantipruriticsforsubjectswithatopicdermatitis.EurJPharmacol,2003.471(3):p.223-8.Kelly,J.X.,etal.,Design,synthesis,andevaluationof10-N-substitutedacridonesasnovelchemosensitizersinPlasmodiumfalciparum.AntimicrobAgentsChemother,2007.51(11):p.4133-40.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792Fax:021-53