NADP-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemENADP(Standard)Cat.No.:HY-113325RCASNo.:53-59-8分?式:C??H??N?O??P?分?量:743.41作?靶點:EndogenousMetabolite作?通路:MetabolicEnzyme/Protease儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性NADP(Standard)NADP的分析標(biāo)準品。本產(chǎn)品?于研究及分析應(yīng)?。NADPisacoenzymeinvolvedincellularelectrontransferreactionsinbiologicalmetabolism,whichisalternatelyoxidized(NADP+)andreduced(NADPH),andcanmaintaincellularredoxhomeostasisandregulatemanybiologicalevents,includingcellularmetabolism.NADPHisauniversalelectrondonorthatprovidesreducingabilityforsyntheticmetabolicreactionsandredoxbalance.NADPHplaysamultifunctionalroleinregulatinginflammation,redoxhomeostasis,andsyntheticmetabolismprocesses[1][4].REFERENCES[1].ChenL,etal.NADPHproductionbytheoxidativepentose-phosphatepathwaysupportsfolatemetabolism.NatMetab.2019Mar;1:404-415.Epub2019Mar11.PMID:31058257;PMCID:PMC6489125.[2].NamTS,etal.Interleukin-8drivesCD38toformNAADPfromNADP+andNAADintheendolysosomestomobilizeCa2+andeffectcellmigration.FASEBJ.2020Sep;34(9):12565-12576.[3].IlterD,etal.NADK-mediateddenovoNADP(H)synthesisisametabolicadaptationessentialforbreastcancermetastasis.RedoxBiol.2023May;61:102627.[4].LeeSH,etal.UpregulationofcytosolicNADP+-dependentisocitratedehydrogenasebyhyperglycemiaprotectsrenalcellsagainstoxidativestress.MolCells.2010Feb28;29(2):203-8.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-58