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生物化學(xué)與分子生物學(xué)(MBBS)智慧樹知到期末考試答案+章節(jié)答案2024年錦州醫(yī)科大學(xué)Thecrosslinkbetweenglycogenesisandglycogenolysisis()

答案:glucose1-phosphateDirectbilirubinissynthesizedat:()

答案:liverOxidativephosphorylationoccursin:()

答案:mitochondriaSubstratelevelphosphorylationisinvolvedin()

答案:1,3-bisphosphoglycerate→3-phosphoglycerateWhichofthefollowingaminoacidcannotproduceonecarbonunit?()

答案:ValineWhatisgeneexpression?()

答案:transcription,translationWhichisanintermediateonthepathwayforsynthesisofketonebodiesandcholesterol?()

答案:HMG-CoAThecontentofwhichofthefollowingelementisclosetoeachotherinvariousprotein?()

答案:NInwhichfollowingconditionsareketonebodiessynthesisgreatlyaccelerated?()

答案:fatmobilizationisenhancedhesub-cellsiteofcholesterolsynthesisis()

答案:cytosol+endoplasmicreticulumWhichofthefollowinglinkthecoreparticleofnucleosome?()

答案:H1WhichoffollowingisindependentofKm?()

答案:enzymeconcentrationWhichofthefollowingmetabolicreactioncannotoccurinliver?()

答案:utilizationofketonebodyThekineticsofenzymaticreactionisthestudyon:()

答案:thevelocityofenzymaticreactionsandinfluenceofvariouselementsonitWhichofthefollowingisnotconcernedwiththecholesterolbiosynthesis?()

答案:NADH+H+Theeffectoftemperatureontherateofenzymaticreactionsis()

答案:eachenzymehasanoptimumtemperatureatwhichitoperatesatmaximalefficiencyWhichoffollowingisthemajororgantoregulatetheconcentrationofglucose?()

答案:liverWhichofthefollowingDNAhasthelowestTm?()

答案:A-Tis80%Thetranslationalinitiationcomplexincludes()

答案:ribosomal+mRNA+Met-tRNAiMetThemajorfactortocontroloxidativephosphorylationinnormalphysiologicalconditionis:()

答案:ADPlevelWhichofthefollowingistheproductofthereplicationcontinuously:()

答案:leadingstrandWhichofthefollowinghormonecanacceleratefatmobilization?()

答案:allotherDuringtheelongationofpolypeptidechaininproteinbiosynthesis,whichsitecanreceipttheaminoacyl-tRNA()

答案:aminoacylsiteWhichoffollowingisnotthecharacteristicsofenzymaticreactions?()

答案:proximityandorientationTheα-subunitofGproteinhavetheactivityof:()

答案:GTPaseMalonatewithsuccinateforsuccinatedehydrogenaseistheclassiccaseof:()

答案:competitiveinhibitionWhichoffollowingisnotcorrectaboutcompetitiveinhibitor?()

答案:itcombineswiththeenzymecovalentlyWhichofthefollowingisnotcorrectaboutprimarybileacid?()

答案:allprimarybileacidarefreeWhichofthefollowingisthecharacteristicofRNA-pol?()

答案:thetranscriptiveproductissynthesizedfrom5′→3′Therawmaterialofcholesterolinthebodyis()

答案:acetyl-CoAWhichofthefollowingaminoacidcontainhydroxylgroup?()

答案:Ser,ThrEveryintegrityproteinmustprocess:()

答案:tertiarystuctureWheredoesdenovosynthesisofpurinenucleotidemainlytakeplace?()

答案:liverThekineticpropertyofnon-competitiveinhibitionis:()

答案:Kmisunchanged,VmaxisdecreasedWhichofthefollowingistheenzymeofpeptidebondformation:()

答案:peptidyltransferaseWhichofthefollowingdonottakepartinthebiotransformationofhemeinliver?()

答案:glucoseDifferentenzymescatalyzesequentialreactionsinthesamepathwayareboundtogetherin()

答案:multienzymecomplexesEnergyforbraininlongstarvationmainlycomesfrom()

答案:ketonebodiesoxidationAfterphosphorylationofglycogensynthaseandphosphrylase()

答案:glycogensynthaseisinactive,phosphrylaseisactiveTheprimarystructureofDNAisthesequenceofitsnucletideresidueslinkedby()?

答案:3’,5’-phosphodiesterbondsWhichofthefollowingarerelatedwithDNAreplicationinitiation?()

答案:topoismerase###helicase###primase###SSBWhichoffollowingiscorrectaboutenzyme?()

答案:enzymesarebiocatalyststhatcatalyzethemultipledynamicprocessesinthebody###enzymesarehighlyspecifictothereactionstheycatalyzeWhichoffollowingiscorrectaboutcovalentmodification?()

答案:havetwoforms:activeformandinactiveform###itmakereactionamplified###itisafastregulation###controlledbyhormoneWhichofthefollowingarethemaintransportationstyleofammoniabetweentissues?()

答案:Alanine###glutaminePropertiesofbindingofHandRare:()

答案:highlyspecificity###highlyaffinity###reversiblebinding###saturationTheendproductofgeneexpressioncouldbe:()

答案:RNA###protein###polypeptidechainTheDNArepairingtypeinclude:()

答案:ExcisionrepairingneedUvrABC###Recombinationrepairing###ExcisionrepairingneedXPprotein###SOSrepairing###LightrepairingWhichofthefollowingabouttrans-actingfactorsarecorrect?()

答案:havemanykinds###couldbindspecialcis-actingelements###areproteinWhichofthefollowingarethepropertiesofα-helixstructure?()

答案:thehelixisrighthanded###thehelixriseupspirallyaroundcentralaxis###onepitchis0.54nm###3.6residuespercircleWhichofthefollowingcouldcatalizethesynthesisofphosphodiesterbond?()

答案:reversetranscriptase###topoismerase###telomerase###DNAligase###DNA-polTheplasmidusedinDNArecombinationtechologyis:()

答案:theindependenthereditaryunitoutsideofthebecterialgenomicDNAAcertainrestricionendonucleasecutDNAbymeansof5′…GGGGGG▼AATTCC…3,’andwillgenerate()

答案:5′salient(突出的)StickyendAcertainrestricionendonucleasecutDNAbymeansofGGG▼CGCCC,andwillgenerate()salientstickyend:()

答案:2nucleotidesWhichofthefollowingcouldnotbeusedasvectorforDNAcloning?()

答案:BacterialgenomeDNAToconstructcDNAlibraryneed:()

答案:reversetranscriptaseandmRNAtemplateWhichofthefollowingisthemostgeneralcharacteristicofthevectorneededinDNAcloning?()

答案:selfreplicationabilityTheprocessofDNAcloningdoesnotinclude()

答案:probesynthesisfortargetgenedetectionWhichofthefollowingistheendthatT4ligasecatalizetolinktogether?()

答案:5′-Pand3′-OHGeneralrecombinationisalsocalled:()

答案:HomologousrecombinationTheoptimalcellsystemtoexpresshumanproteinis()

答案:mammaliacellexpressionsystemWhichofthefollowingaboutC-onciscorrect?()

答案:expressionproductofoncogeneisfucntionalproteininnormalcellphysiologialaction###c-onccouldbedetectedinnomalhigheranimalcells###v-oncisnucleotidesequenceexistedintumorvirusWhichofthefollowingaboutC-oncisnotcorrect?()

答案:alsonamedvirus-oncogene###existinRNAvirus###existinviralDNAWhichofthefollowingbelongtoanti-oncogene?()

答案:p53Whichofthefollowingarenottheexpressionproductofoncogene?()

答案:cis-actingelementWhichofthefollowingelementcouldactivateoncogene?()

答案:pointmuationofoncogeneWhichofthefollowingdoesnotbelongtooncogene?()

答案:RbWhichofthefollowingbelongtooncogenexpressionproduct?()

答案:growthfactorreceptors###growthfactor###intranucleartranscriptionfactor###signalmoleculorparticipatecellularsignaltransductionWhichofthefollowingaboutoncogeneisnotcorrect?()

答案:normalcellshavenooncogeneTheoncogenewouldbeactivatedinthefollowingofsituation:()

答案:genemutation###proto-oncogeneamplification###chemcialcarcinogensexistence###radioactiveray###beinfectedbycancer-inducingvirusWhichofthefollowingcouldinducecellcanceration?()

答案:genedamagedbyphysicalandchemicalcarcinogenicagent###virus-oncogeneincorporatethecellandexpression###pointmutationofoncogene###thelostorinactivationofanti-oncogeneWhichofthefollowingbelongtooncogene?()

答案:ras###sis###erb-BWhichofthefollowingaboutpropertiesofbindingofhormoneandreceptorisnotcorrect()。

答案:covalentbondingTheαsubunitofGproteinhavetheactivityof()。

答案:GTPaseWhichofthefollowingdoesnotbelongtosecondmessenger()。

答案:PIP2WhichofthefollowingdoesnotparticipateinAC-cAMP-PKApathway()。

答案:cGMPGproteinisreferredto()。

答案:GTPbindingproteinWhichofthefollowingdonotparticipateincellularsignaltransduction()。

答案:NAD+SignaltransductionpathwaymediatedbyEGFreceptorconsistof()。

答案:ERK###RTK###MEK###Ras###RafThechemicalnatureofintracellularreceptorsis()。

答案:DNAbindingproteinWhichcancauseendoplasmicreticulumreleaseCa2+()。

答案:IP3Extracellularchemicalmoleculesinclude()。

答案:endocrinehormones###paracrinesignals###neurotransmittersWhichofthefollowinggeneraltranscriptionfactorscanrecognizeandbindtoTATAboxdirectly()。

答案:TFⅡDOperonsdonotinclude()。

答案:trans-actingfactorWhichofthefollowingbelongstoacis-actingelement()。

答案:enhancerWhichofthefollowingdoesnotbelongtogeneexpression()。

答案:ThereplicationofRNAThestructureoflacoperonconsistof()。

答案:onepromoter###threestructuralgenes###Igene###oneoperatorWhichofthefollowingbelongstoatrans-actingfactor()。

答案:transcriptionfactorWhichinducesthetranscriptionoflacoperon()。

答案:allolactoseWhenthetryptophanlevelsarehigh,thetryptophanoperonisregulatedby()。

答案:attenuator###negativeregulation###repressorproteinWhichisboundbyRNApolymeraseandinitiatestranscription()。

答案:promoterThegeneralregulatorypointofgeneexpressionis()。

答案:transcriptioninitiationThesubstancethatisnotneededforproteinbiosynthesisis()。

答案:DNAWhichofthefollowingtRNAanticodonismatchedwithmRNAcodonACG()。

答案:CGUAminoacyl-tRNAsynthetasehasspecificityfor()。

答案:aminoacidandtRNAWhichenzymecatalyzestheformationofpeptidebond()。

答案:transpeptidaseWhichofthefollowingmaterialcancarrythegeneticinformationofDNAtothecytoplasmandtoguidethebiosynthesisofprotein()。

答案:mRNAWhatcomponentsareneededfortheribosomecycle()。

答案:elongationfactor###mRNA###aminoacyl-tRNA###ribosome###GTPTheintroductionofeukaryoticsecretoryproteinsintotheendoplasmicreticulumis()。

答案:signalpeptideTheenergyrequiredforpeptidechainelongationinprokaryoticproteinbiosynthesisis()。

答案:GTPInthecharacteristicsofthecodons,theframeshiftmutationisrelatedto()。

答案:non-punctuationandnonoverlappingSubstancesinvolvedinproteinbiosynthesisare()。

答案:ATP###aminoacid###tRNA###GTP###mRNAThetranscriptofRNApolymeraseIineukaryotesis()

答案:45SrRNAWhichsubunitofRNApolymeraseisthespecificbindingsiteofRifampicininprokaryotes?()

答案:βsubunitThetranscriptoftemplate5'-ACTAGTCAT-3'is()

答案:5'-AUGACUAGU-3'TheprimaryroleofRNApolymeraseⅢistosynthesis()

答案:tRNAand5SrRNAWhichoneiscorrectabouttheexon?()

答案:TheDNAsequencethatistranscribedandtranslatedWhichsubunitofRNApolymerasecanrecognizethetranscriptionstartsiteinprokaryotes?()

答案:σsubunitThebindingsiteofTFⅡDis()

答案:TATAboxFeather-likestructureoftranscriptionunderelectronmicroscopeindicates()

答案:translationwasinitiatedbeforethetranscriptiontermination.WhichonecaninhibitprokaryoticRNApolymerasespecifically?()

答案:RifampicinRNAholoenzymeincludesσsubunit,itbindswithDNAtemplatestrandattheinitiationofthetranscription.Intheelongationstage,theσsubunitwill()

答案:dissociatefromtheholoenzymeintheelongationstage.WhichofthefollowingisthelargerfragmentofDNApolⅠ?()

答案:KlenowfragmentThematerialsofDNAsynthesisare:()

答案:dATP,dGTP,dCTP,dTTPWhichoftheseenzymeisnotconcernedwithDNAreplication?()

答案:RNAdependentDNApolymeraseTheprokaryoticDNA-polcoreenzymeismadeupwith()?

答案:αεθWhichofthefollowingserveastheenzymeinmitochondriaDNAreplication?()

答案:DNApolγInDNAreplication,whatisthereasonofOkazakifragmentgenerated?()

答案:thedirectionofreplicationisdifferentwiththedirectionofunwindingDNAandRNAarecomposedoffourtypesofdeoxyribonucleotidesandribonucleotides,respectivelylinkedwith()?

答案:3’,5’-phosphodiesterWhichofthefollowingistheproductofthereplicationdiscontinuously?()

答案:OkazakifragmentWhichofthefollowingcouldproofreading,DNArepairing,fillingofgaps?()

答案:DNApolⅠIntheinitiationofDNAreplication,theproperorderthatfollowingenzymeandproteinactingis?1,DNA-polⅢ2,SSB3,primase4,helicase()

答案:4,2,3,1IntheprokaryoticDNAreplication,whichofthefollowingisNOTneeded?()

答案:PCNAThecommondonorsoftheconjugatedsubstancesare()inthephaseIIreactionoftheliver.

答案:UDPGA###acetylCoA###PAPS###SAMWhichofthefollowingisnotthedonatorofbiotransformation?()

答案:UDPGWhichisthemostimportantenzymetakingpartintheoxidationreactionofthebiotransformation?()

答案:monooxygenaseThemostimportantphaseIreactionofthebiotransformationis()

答案:oxidationreactionThemostrelevantofthebiotransformationprocessinliveris()

答案:cytochromeP450Themostsignificanceofthebiotransformationisto().

答案:increasethesolubilityofthenon-nutritionalsubstanceandeliminatefromthebodyThemostimportantphaseIIreactioninthebiotransformationis().

答案:combinewithglucuronicacidNon-nutritionalsubstancecan()afterbiotransformation.

答案:decreasethedrugactivity###decreasethetoxicity###excretefromthebileacidorurine###increasethewatersolubilityWhichofthefollowingcanprovideactivemethylgroup?()

答案:SAMWhichofthefollowingcanprovideactivesulphate?()

答案:PAPSWhichofthefollowingistheenzymethatcatalyzethesynthesisofuricacid?()

答案:xanthineoxidaseWhichofthefollowingisnotthedirectmaterialofdenovosynthesisofpurinenucleotide?()

答案:glutamateWhichofthefollowingsubstancedirectlylinknucleotidesynthesisandglucosemetabolism?()

答案:glucose-6-phosphateWhichofthefollowingisthemethylgroupdonorofTMP?()

答案:N5,N10-CH2-FH4Whichofthefollowingistheendproductionofpurinenucleotidecatabolicmetabolism?()

答案:uricacidWhichofthefollowingmaterialcouldprovideC4andC5forpurinering?()

答案:GlycineWhichofthefollowingistheanalogueofazaserine?()

答案:glutamineWhichofthefollowingisdirectlyreduced,andproducedeoxynucleotide?()

答案:NDPWhichofthefollowingisthecommonmaterialforthesynthesisofpyrimidineandpurinenucleotide?()

答案:glutamineWhichofthefollowingisfirstsynthesizedintheprocessofdenovosynthesisofpurinenucleotide?()

答案:IMPIntheprocessofureacycle,whichofthefollowingsubstancecangooutmitochondrion?()

答案:citrullineWhichofthefollowingisnotproducedbyTyr?()

答案:PheWhichofthefollowingisnotonecarbonunit?()

答案:CO2Inthesynthesisofurea,oneNcomefromNH3,anotherNcomefrom()directly?

答案:AspWhichofthefollowingisnottheoutletofα-ketoacidthatproducedbydeaminationofaminoacid?()

答案:beconvertedtoessentialamminoacidWhichofthefollowingisthecarrierofonecarbonunit?()

答案:FH4WhichofthefollowingisthedirectdonorofCH3?()

答案:SAMWhichofthefollowingisthestorageandtransportationstyleofammonia?()

答案:GlnWhichofthefollowingisonlyketogenicaminoacid?()

答案:LeucineWhichofthefollowingaminoacidcanproducePAPS?()

答案:cysteineThemajorfunctionofHDLis()

答案:reversecholesteroltransportCholineisactivatedintheformof(),beforeitentersdiacylglycerolpathway.

答案:CDP-cholineThelipoproteinthattransferendogenouscholesterolis:()

答案:LDLWhichoffollowingdoesnotutilizeketonebodies?()

答案:liverWhichisthemajorformthattransportsexogenousTAGstothecirculation?()

答案:CMWhichisthemajorformthattransportsendogenousTAGsfromthelivertothetissues?()

答案:VLDLWhichisnotrequiredinβ-Oxidationoffattyacids?()

答案:NADP+Intheliver,()istherate–limitingenzymeonthepathwayforsynthesisofcholesterol.

答案:HMGCoAreductaseHowmanymolsofATPareyieldedwhen1molstearicacid(18C)isoxidizedtoCO2andH2O?()

答案:120NADPHinfattyacidsynthesiscomesfrom:()

答案:pentosephosphatepathwayThecharacteristicofbiologicaloxidationis()

答案:energyreleasedgraduallyandhighavailabilityWhichofthefollowingenzymeusesFADasprotheticgroup?()

答案:succinatedehydrogenaseThecoenzymeofα-glycerophosphatedehydrogenaseinmitochondriais:()

答案:FADWhichofthefollowingmetabolicprocessiscompletedinmitochondriontotally()

答案:oxidativephosphorylationWhichoffollowingisthecarrierofNADHfromcytosoltomitchondria?()

答案:malateWhichofthefollowingisnottheenergy-richcompound?()

答案:2,3-bisphoglycerateWhichagentisaninhibitorofelectrontransportatComplexⅢ?()

答案:antimycinAHowmanyATPswillbeproducedwhen1cytosolicNADHistransportedintothemitochondriabyα-glycerophosphateshuttle?()

答案:1.5TheorderofNADHrespiratorychainis:()

答案:NAD+→complexⅠ→CoQ→complexⅢWhichofthefollowingisthemostimportantelementintheregulationofoxidativephosphorylation?()

答案:[ADP]/[ATP]Whichismetabolizedthroughboththeglycolyticpathwayandthepentosephosphatepathway?()

答案:glucose6-phosphateHowmanyATPsareproducedbytheoxidationofamoleculeofaceylCoAviathecitricacidcycle?

答案:13Substrate-levelphosphorylationincitrateacidcycleis:()

答案:succinyl-CoA→succinateTheend-productofglycolysisis:()

答案:lactateThekeyenzymeoftheglycolysisis:()

答案:pyruvatedehydrogenaseWhyerythrocytesmetabolizeglucosebyanaerobicglycolysis?()

答案:lackofmitochondriaWhichoffollowingisnotthekeyenzymeinaerobicoxidationofcarbohydrate?()

答案:succinatedehydrogenase1moleculeofpyruvatewhichisoxidizedcompletelymaygenerate()moleculesofATP.()

答案:12.5WhichoffollowinggenerateFADH2afterdehydrogenation?()

答案:succinateWhatarethemostimportantproductsthecellsgeneratebymeansofthepentosephosphatepathway?()

答案:ribose-5-phosphateandNADPHWhichoffollowingisnotcorrectaboutLDHisoenzymes?()

答案:havethesameKmtothesamesubstrateTherelationshipbetweencompetitiveinhibitorandsubstrateisthattheyhave:()

答案:similarstructureWhichoffollowingisnotcorrectaboutKm?()

答案:KmisindependentofenzymestructureWhichoffollowingiscorrectaboutcharacterofenzyme?()

答案:allgroupsinactivesitearetermedtheessentialgroupsWhichoffollowingisnotcorrectaboutallostericenzyme?()

答案:allostericeffectorbindstoactivesiteofenzymeIsoenzymesareenzymesthat:()

答案:catalyzethesamereactionWhichoffollowingisnotcorrectaboutactivesiteofanenzyme?()

答案:itisformedbygroupsthatprimarystructureisclosetoeachotherinthepolypeptidesequenceWhichoffollowingisnotcorrectaboutcovalentmodification?()

答案:activityofenzymeincreasedafterphosphorylatedSpecificityofenzymerefersto

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