醫(yī)學(xué)考老師大閱讀篇

大閱讀9小白老師醫(yī)學(xué)考博英語(yǔ)網(wǎng)絡(luò)課AnatlasofwhereproteinsarefoundinONEof大閱讀9小白老師醫(yī)學(xué)考博英語(yǔ)網(wǎng)絡(luò)課AnatlasofwhereproteinsarefoundinONEofthemostimportantconceptsinbiologyisDifferentorgansdodifferentjobswithinbodies.Differenttissuesdodifferentwithinorgans.Differentcellswithintissues,likewise.Andwithincells,organelles—assubcellularcomponentssuchasnuclei,mitochondriaandbodiesareknown—arealsospecialisedforparticularfunctions.Eachoftheseoforganisationhas,overtheyears,inwhathavecometobeasatlases,beginningin1543withAndreasVesalius’s“DeHumaniCorporis(OntheFabricoftheHumanBody),thefoundingtextofmodernThelatestlevelofdetailistolookatdifferentproteinswithinProteinsarethemoleculesthatdomostoftheworkwithinacell.Theyrangethingslikeactinandmyosin,whichcollaboratetoflexmusclecells—andthusmusclesofwhichthosecellsarepart—totheenzymesoftheKrebscycle,disassembleglucosetoreleasethe.TheCellAtlas,alaunchedonDecember4thatameetingoftheAmericanSocietyofCellrecordswhichproteinsarefoundinwhichorganelles.Theresult,like“DeCorporisFabrica”,isbothpleasingtotheeyeandimportanttothefield.locatedtogetherarelikelytoworktogether,soknowingaprotein’swithinacellwillhelpresearcherstodetermineitsTheauthorsoftheCellAtlas,ledbyMathiasUhlenoftheRoyalInstituteTechnology,inStockholm,havepinned12,051proteinsdowninthiswayimmunofluorescence.Thistechniqueemploysspeciallycreatedantibodiesmolecules,producedbyimmune-systemcells,thatbindspecificallytoatargetprotein)tohuntdownthattargetwithinacell.Theantibodiestagsattachedtothem,sothattheywillglowwhenexposedultravioletlight.Byapplyingthesetaggedantibodiestocellsfrom22human-cellderivedfromarangeoforiginaltissues,theatlas’sauthorsgavethemselvesthe1/possiblechanceofdetectingaparticularproteinincellsofatleastoneline.done,eachsamplepossiblechanceofdetectingaparticularproteinincellsofatleastoneline.done,eachsamplewasexaminedmicroscopicallytodeterminewhichofthegenerallyrecognisedorganelleseachproteinappearedin.This,beingquitea(andnotoneeasilydelegatedtoautomaticoptical-recognitionsystems),wasoutinpartbyabunchof120,000enthusiasticTheexampleinthepictureisofthedistributionofaprotein(taggedcalledZNF554.Thisbelongstoagroup,thezinc-factors,jobistoactivateandregulategenes.Asthepictureshows,ZNF554isrestrictedthecell’snucleus.Withinthatnucleusthereareseveralplaceswhichparticularlybrightly,andwhereitisthereforeparticularlyabundant.Thesearenucleoli—zoneswheregenesareespeciallyactive.(Theredareasarethemicrotubules.TheseactasandaretaggedinallCellAtlaspictures,ordertooutlineacell’sWhatfractionofhumanproteinstheCellAtlascurrentlycoversisopendebate.Thenumberofprotein-codinggenesinthehumangenomeisreckonedat19,628.Somegenes,however,canyieldmorethanoneprotein—becausetheymaybereadinmorethanoneway,orbecausetheirmessagestoprotein-manufacturingpartsofacellmayendupeditedindifferentways.meanstheactualnumberofproteinsthatcanexistfromtimetotimeintheexceedsthenumberofgenes,probablybyatleast50%.TheCellAtlas,then,isbymeansthelastwordonthematterofwhereproteinsarefound.Butitisagood1.catalogue英 美[?k?tl??ɡ,-n.目錄，一覽表（美）vt.為…編目錄；登記分類