梳狀聚合物分散劑 穩(wěn)定劑Agrilan 755 China April,2012 CN

Agrilan755–Stabilizer

Ournewcomb-polymericdispersant

梳狀聚合物

穩(wěn)定劑

/分散劑

SurfaceChemistryAgrilan755-CombpolymersHydrophobicbackbone（憎水主鏈）Hydrophilicchains(親水)ExcellentstabilizersforSCandSE（優(yōu)異的對SC和SE的穩(wěn)定性）ExcellentdispersantsforSCandSE–stericstabilization（優(yōu)異的對SC和SE的分散性能–空間立體穩(wěn)定性）Highmolecularweight（高分子量）SurfaceChemistrySurfaceChemistry3Agrilan755Overthepastfewyearspesticideformulationshavebecomemorecomplex–

在過去的若干年里，農(nóng)藥的成分越來越復(fù)雜MultipleactivesinSC懸浮劑中更多的原藥成分

Suspoemulsions(SE懸乳劑

)–dispersedandemulsifiedphases懸乳劑中同時(shí)含有分散相和乳化相As分散劑&stabilizers穩(wěn)定劑withmultipleactivesorwhenanoilphaseisincluded

在多種原藥或者有油相存在的系統(tǒng)中，作為分散劑和穩(wěn)定劑。SurfaceChemistryAgrilan755Stabilizer（Agrilan755穩(wěn)定劑）

Howitworks（工作原理）

Manyanchoringgrouppermoleculeofthehydrophobicbackboneadsorbsontothesurfaceofaparticle憎水主鏈上的大量特殊基團(tuán)吸附于原藥表面HydrophilicPEGchainsextendintotheaqueousphaseprovidingstericstabilization(親水PEG鏈伸展入，提供了很好的空間穩(wěn)定性)(-)(-)(-)(-)(-)Weakanionicgroupsprovideelectrostaticrepulsion弱陰離子基團(tuán)提供電荷排斥Conventiondispersant/Emulsifier傳統(tǒng)的分散/乳化劑Polymericdispersant/Emusifier聚合分散/穩(wěn)定劑ActiveActiveSurfaceChemistry

HydrophilicPEGchainsextendintotheaqueousphaseprovidingstericstabilization(親水PEG鏈在伸展入均相介質(zhì)，提供了很好的空間穩(wěn)定性)(-)(-)(-)(-)(-)Weakanionicgroupsprovideelectrostaticrepulsion弱陰離子基團(tuán)提供靜電排斥Attraction

吸引力Repulsion排斥力Distancecurvebetween2particles(兩微粒間距曲線)空間穩(wěn)定性靜電穩(wěn)定性靜電+空間穩(wěn)定性(-)(-)Agrilan755Stabilizer（Agrilan755穩(wěn)定劑）

Howitworks（工作原理）Active

(-)(-)(-)(-)(-)(-)Active(-)SurfaceChemistrySurfaceChemistry6WhyAgrilan755plusanotherdispersant(MorwetD425)?

為什么Agrilan755其他分散劑（MorwetD425）配合使用效果更好？Morwetdispersantsaremoreanionic(polar)thanAgrilan755–thecombinationinducesstrongelectro-stericstabilization(Morwet比Agrilan755陰電性（極性）更強(qiáng)，與Agrilan755配合使用可提供更好的電荷-空間穩(wěn)定性Repulsion排斥力Attraction

吸引力Verypolaractivescanbeflocculatedbyanionicdispersants–thecombinationofAgrilan755+EthylanNS-500LQ/324providesstericstabilization

極性非常強(qiáng)的原藥，在單純使用陰離子分散劑時(shí)，仍可能產(chǎn)生絮凝–如果使用Agrilan755+EthylanNS-500LQ/324可提供很好的空間穩(wěn)定性SurfaceChemistry-AGROApplicationsSteric/ElectrostaticStabilization

空間/靜電穩(wěn)定性CombinationofD425+Agrilan755/EthylanNS500LQ（D425+Agrilan755/EthylanNS500LQ混合）Electrostaticcomponentsnotsensitivetotemperaturechanges

靜電的部分對溫度變化不敏感Stericcomponentsnotsensitivetoelectrolytechanges空間位阻的部分對電荷變化不敏感----------SurfaceChemistrySurfaceChemistry8AdvantageofAgrilan755plusanotherdispersant(MorwetD425)

Agrilan755加上另外一個(gè)分散劑（MorwetD425）Coninued…..LowerMWdispersants(MorwetD425)migratefasterthanstabilizerstoasurfaceorinterfaceforquickviscosityreduction

低分子量的分散劑（MorwetD425）比穩(wěn)定劑遷移快，更快地達(dá)到原藥表面/界面，產(chǎn)生快速的粘度下降MorwetD425canbeusedinSCasmillingaid

providesgoodwetting,dispersingandmilling

propertieswiththe755stabilizeraddedaftermilling

Morwet

D425提供了很好的潤濕性，分散性和研磨性，可作為懸浮劑研磨助劑，755作為穩(wěn)定劑，在研磨后添加SurfaceChemistryDispersantEfficiency:Millingperformancecanbepredictedbyviscosity

分散劑效果：可以通過粘度變化來預(yù)測研磨的效果

GoodreductioninviscosityModeratereductioninviscosityNoreductioninviscosity分散劑-粘度關(guān)系曲線粘度分散劑粘度不下降中等粘度下降高粘度下降SurfaceChemistryDispersantEfficiency(分散效率)

Alargereductioninviscosityindicatesexcellentdispersantefficiency

粘度大大降低表示分散效率非常高Couldindicategoodadsorption

表示吸收好Maximumreductioninflocculation

最大限度降低絮凝Bestpotentialfornoviscosityincreaseduringmilling

最有可能在研磨時(shí)不增加粘度Lowviscositymeansfasterthroughput

低粘度意味著高產(chǎn)率

SurfaceChemistry11SummaryofMorwetD425對MorwetD425的總結(jié)

MORWETD425(2.5-3%)SecondaryfunctionasMillingaid:Providequickviscosityreduction&wetting(第二個(gè)功能是研磨助劑，提供快速的粘度降低和潤濕)FIFRAandREACHapprovedFIFRA和REACH批準(zhǔn)PrimaryfunctionasDispersantAgent(主要作為分散劑)Agrilan755/EthylanNS500LQ/324SurfaceChemistrySC/SERECOMMENDATION

懸浮劑/懸乳劑配方推薦

PRIMARYDISPERSANT(分散劑)MorwetD425Agrilan700(雪白色分散劑)CO-DISPERSANT/STABILIZER/WETTING輔助分散劑/穩(wěn)定劑/潤濕劑）Agrilan755BlockCopolymers

嵌qian段duan共聚物-EthylanNS-500LQ-EO/PO的嵌段共聚物，HLB14.1;傾點(diǎn)-8?C-EthylanNS-505K-EO/PO的嵌段共聚物，HLB14.1;傾點(diǎn)29?-Ethylan324-EO/PO的嵌段共聚物，HLB8.0;傾點(diǎn)36?C

SurfaceChemistryADVANTAGEOFUSINGAGRILAN755

CO-DISPERSANT/STABILIZER

使用Agrilan755輔助分散劑/穩(wěn)定劑的優(yōu)點(diǎn)Avoidsurfactantthatcanformmicelleandsolubilizeactive避免表面活性劑形成膠束su并穩(wěn)定原藥WHY?為什么？SurfaceChemistryBelowCMC低于臨界膠束濃度AboveCMC高于臨界膠束濃度

MicelleisaSolubilizer

膠束是一種溶劑CMCistheconcentrationofsurfactantwheremicelleformationinitiates

臨(lin)界膠束(su)濃度是膠束剛開始形成時(shí)的表面活性劑濃度CMCfornonionicsurfactantsaremuchlowerthanforanionics.

非離子表面活性劑的臨界膠束濃度要比陰離子型低得多Example如C12E5=0.02g/lSDS=3g/lNonionicswithlowCMCtendtosolubilizeandwillinducecrystallization

具有低的臨界膠束濃度的非離子型表面活性劑，比較容易穩(wěn)定但會引起結(jié)晶SurfaceChemistryCrystalGrowth

晶體生長Highsolubilityoftheactive

原藥的高溶解性>200ppminwater

在水中>200ppmSurfactantsandsolventsmayincreasesolubility表面活性劑和溶劑可提高溶解性Choiceofsurfactant

表面活性劑的選擇i)PolymericsurfactantlikeAgrilan755–Doesnotformmicelles(anticrystalformation)聚合型表面活性劑，如Agrilan755，不會形成膠束，具有抗結(jié)晶特性ii)BlockcopolymersStrongadsorptionofcouldreducecrystalgrowth(EthylanNS500LQorEthylan324)嵌段共聚物的高吸收附可以減少結(jié)晶SurfaceChemistry-AGROApplicationsAnalysis&Evaluation

分析和評估

BromoxynilSC

溴苯腈SC

SCwithMorwetD-425添加D425后的懸浮劑SCwithTSP-PhE添加TSP-PhE后的懸浮劑SurfaceChemistry17Agrilan?755Robustproducttobeusedinallkindofformulation(non-aqueoussystemsaqueoussystemsi.eSC/SE適用于各種配方（均相系統(tǒng)和非均相系統(tǒng)，如懸浮劑、懸乳劑)Manyanchoringsite,adsorbsstrongly,&highMW,Bett