Histone-Acetyltransferase-Inhibitor-II - Histone Acetyltransferase 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEHistone Acetyltransferase Inhibitor IICat. No.: HY-100734CAS No.: 932749-62-7分式: CHBrO分量: 464.15作靶點(diǎn): Histone Acetyltransferase作通路: Epigenetics儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO :

2、 30 mg/mL (64.63 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.1545 mL 10.7724 mL 21.5448 mL5 mM 0.4309 mL 2.1545 mL 4.3090 mL10 mM 0.2154 mL 1.0772 mL 2.1545 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請根據(jù)您的實(shí)驗(yàn)動物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次?/p>

3、加助溶劑(為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (5.39 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE物活性 Histone Acetyltransferase Inhibitor II種有效的

4、，細(xì)胞滲透的 p300 抑制劑，IC50 值為 5 M，可于癌癥研究。IC50 & Target IC50：5 M (p300) 1體外研究 Histone Acetyltransferase Inhibitor II種有效的，細(xì)胞滲透的 p300 抑制劑，IC50 值為 5 M，可于癌癥研究。REFERENCES1. Costi R, et al. Cinnamoyl compounds as simple molecules that inhibit p300 histone acetyltransferase. J Med Chem. 2007 Apr19;50(8):1973-7. Epub 2007 Mar 10.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: