Dyclonine-hydrochloride-Dyclocaine-hydrochloride-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEDyclonine hydrochlorideCat. No.: HY-B0364ACAS No.: 536-43-6Synonyms: Dyclocaine hydrochloride分式: CHClNO分量: 325.87作靶點(diǎn): Sodium Channel作通路: Membrane Transporter/Ion Channel儲存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-

2、20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) H2O : 50 mg/mL (153.44 mM; Need ultrasonic)DMSO : 25 mg/mL (76.72 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 3.0687 mL 15.3435 mL 30.6871 mL5 mM 0.6137 mL 3.0687 mL 6.1374 mL10 mM 0.3069 mL 1.5344 mL 3.0687 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合

3、適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實(shí)驗(yàn)請根據(jù)您的實(shí)驗(yàn)動物和給藥式選擇適當(dāng)?shù)娜芙獍?，配制前請先配制澄清的儲備液，再依次添加助溶?為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (7.67 mM); Clear solution2. 請依序添加每種溶劑： 10% DMSO 90% (20% SBE-CD in sal

4、ine)1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemESolubility: 2.5 mg/mL (7.67 mM); Clear solution3. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (7.67 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Dyclonine hydrochloride潤喉的有效成分。REFERENCES1. Florestano, H.J. and M.E. Bahler, Antimicrobial pro

5、perties of dyclonine hydrochloride, a new topical anesthetic. J Am Pharm Assoc AmPharm Assoc (Baltim), 1956. 45(5): p. 320-5.2. Gargiulo, A.V., G.M. Burns, and C.P. Huck, Dyclonine hydrochloride-a topical agent for managing pain. Ill Dent J, 1992. 61(4): p. 303-4.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-5