1-Naphthyl-PP1-1-NA-PP-1-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemE1-Naphthyl PP1Cat. No.: HY-13941CAS No.: 221243-82-9Synonyms: 1-NA-PP 1分式: CHN分量: 317.39作靶點(diǎn): Src作通路: Protein Tyrosine Kinase/RTK儲(chǔ)存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 14.25 mg/mL (

2、44.90 mM; Need ultrasonic and warming)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲(chǔ)備液1 mM 3.1507 mL 15.7535 mL 31.5070 mL5 mM 0.6301 mL 3.1507 mL 6.3014 mL10 mM 0.3151 mL 1.5753 mL 3.1507 mL請(qǐng)根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲(chǔ)備液，并請(qǐng)注意儲(chǔ)備液的保存式和期限。BIOLOGICAL ACTIVITY物活性 1-Naphthyl PP1(1-NA-PP 1)是src家族抑制劑，對(duì)v-Src，c-

3、Fyn，c-Abl，CDK2和CAMK II的IC50分別為1.0，0.6，0.6，18和22 _mu_M。戶使本產(chǎn)品發(fā)表的科研獻(xiàn)1/2 Master of Small Molecules 您邊的抑制劑師www.MedChemE Plant J. 2019 Mar;97(5):970-983.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Bishop AC, et al. A chemical switch for inhibitor-sensitive alleles of any protein

4、kinase. Nature. 2000 Sep 21;407(6802):395-401.2. Tandon M, et al. New pyrazolopyrimidine inhibitors of protein kinase d as potent anticancer agents for prostate cancer cells. PLoS One.2013 Sep 23;8(9):e75601.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: 021-