宮頸癌固定野調(diào)強(qiáng)和容積旋轉(zhuǎn)調(diào)強(qiáng)放療計(jì)劃劑量學(xué)分析

1、宮頸癌固定野調(diào)強(qiáng)和容積旋轉(zhuǎn)調(diào)強(qiáng)放療計(jì)劃劑量學(xué)分析宮頸癌固定野調(diào)強(qiáng)和容積旋轉(zhuǎn)調(diào)強(qiáng)放療打算劑量學(xué)分析1959202109-0082-03Abstract：Objective To compare the dosimetric differences between fixed field intensity IMRT and volumetric rotational intensity VMAT in cervical cancer radiotherapy. Methods 20 patients with cervical cancer who underwent supine radiot

2、herapy were enrolled. After planning the target area and jeopardizing the organs， the treatment dose of PTV 50 Gy/25 was planned. Each patient was designed with 5 wild IMRT and 2 arc VMAT. Use the same optimization parameters. Evaluation of target VPTV105%， Dmin， uniformity index HIptv， conformality

3、 index CIptv; risk of organ OAR average dose Dmean， V40， V30， V20; difference in machine hop MU and treatment time Time Evaluate and conduct statistical analysis. Results The VPTV105%， Dmin， HIptv， and CIptv were better than the IMRT in the two groups，the difference was statistically significant P0.

4、05. The mean bladder dose Dmean， V40， and V30 of VMAT were better than IMRT in the two groups，the difference was statistically significant P0.05. There was no significant difference in the doses of the femoral head and rectum between the two groups P0.05. The MU and Time of VMAT were better than IMR

5、T in the two groups，the difference was statistically significant P0.05. Conclusion Compared with IMRT， VMAT has a better dose distribution in the target area of cervical cancer radiotherapy， and the bladder irradiation volume and average dose are smaller. There is no obvious advantage in the femoral

6、 head and rectum on both sides. The number of treatment hops is greatly reduced， the loss to the accelerator is relatively small， and the treatment time of the patient is significantly reduced. Without considering the economic factors of treatment costs， the VMAT treatment plan further increases the dose distribution in the target area， provides better protection of the bladder， and has a better dosimetric advantage. 0.05;兩組打算中VMAT的平均機(jī)器跳數(shù)和平均治療時(shí)間優(yōu)于IMRT，差異具有統(tǒng)計(jì)學(xué)意義P0.05;兩組打算中VMAT的MU和Time均優(yōu)于IMRTP<0.05，這是VMAT的一個(gè)顯著優(yōu)勢(shì)。綜上所述，與IMRT相比，VMAT在宮頸癌放療的靶區(qū)劑量分布更優(yōu)，膀胱的照射體積和平均劑量更小，兩側(cè)股骨頭和