Clinical studies of vacuum sealing drainage (VSD正

1、Clinical studies of vacuum sealing drainage (VSD) applications in wound healing in pressureProject Summary Study the effects of different pressure on the wound Include: wound blood flow Bacterial clearance Growth of granulation tissue Re-epithelialization rateThe foundation (A) domestic research In

2、1994, Professor Qiu Huade the first to introduce the technology Two decades has been recognized at home and abroad and is widely used in clinical Now nationally recognized pressure (0.04-0.06Mpa)The foundation (B) foreign research status Fleischtnann recommended negative pressure 450-600mmHg (0.06-0

3、.08Mpa) Morykwas through experimental and clinical studies, the proposed 75-125mmHg (0.01-0.02Mpa) negative pressure to the wound increased perfusion. Vacuum-assisted closure wound different pressures on local blood flow, bacterial clearance rate, the growth of granulation tissue and re-epithelializ

4、ation rate impact, is also been reported.Fleisehmann W，Streeker W，et al.Vacuum sealing as treatment of soft tissue damage in open fractures Unfall chirurg，1993;96(9):488-492Morykwas MJ，Argenta LC，Shelton-Brown EI，et al. Vaeuum assisted closure: a new method for wound control and treatment: animal st

5、udies and basic foundation. Ann Plast Surg, 1997; 38(6):553-562.The foundation （C）Research Significance To summarize the clinical experience Provide a theoretical basis for clinical treatmentThe foundation (D) the key issues to be addressed 1, the establishment of animal wound models; 2, to explore

6、the negative pressure test size.References 1、史立偉,余晶晶,李郵等.我國(guó)道路交通傷的研究進(jìn)展J.浙江創(chuàng)傷外科,2008,13(3):32-34. 2、Fleisehmann W，Streeker W，et al.Vacuum sealing as treatment of soft tissue damage in open fractures Unfall chirurg，1993;96(9):488-492 3、Fleisehmann W,Lang E,Kinzl L.Vaeuum assisted wound closure after de

7、rma of asciotomy of the lower extremity. Unfall chirurg，1996;99(4):283-287. 4、Morykwas MJ，Argenta LC，Shelton-Brown EI，et al. Vaeuum assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg, 1997; 38(6):553-562. 5、ArgentaL C，Morykwas MJ. Vaeu

8、um-assisted closure: a new method for wound control treatment: clinical experience. Ann Plast Surg, 1997; 38(6): 563-576. 6. Roy N, Shah H, Patel V, Bagalkote H (2005) Surgical and psychosocial outcomes in the rural injureda follow-up study of the 2001 earthquake victims. Injury 36(8):927 7. Kovacs

9、L, Kloppel M, Geishauser S, Schmiedl S (1998) Vacuum sealing: a new and promising regimen in the therapy of radiation ulcers. Br J Surg 85:70References 8. Mllner T, Mrkonjic L, Kwasny O, Vcsei V (1997) The use of negative pressure to promote the healing of tissue defects: a clinical trial using the

10、vacuum sealing technique. Br J Plast Surg 50(3):194199 9. Fleischmann W, Strecker W, Bombelli M, Kinzl L (1993) Vacuum sealing as treatment of soft tissue damage in open fractures. Unfallchirurg 96(9):488492 10. Fleischmann W, Russ M, Westhauser A, Stampehl M (1998) Vacuum sealing as carrier system

11、for controlled local drug administration in wound infection. Unfallchirurg 101(8):649654 11. Beno M, Martin J, Hatzl J (2010) Vacuum sealing in the treatment and prevention of prosthetic infectionsa case review. Rozhl Chir 89(8):508512 12. Fleischmann W, Lang E, Russ M (1997) Treatment of infection

12、by vacuum sealing. Unfallchirurg 100(4):301304 13. Li X, Wang H, Zhang C, Chen K, Zhuang L, Ding B (2010) Repair of skin and soft tissue defects of lower limbs with vacuum sealing drainage combined with flaps. Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 24(6):722725References 14. Gustilo RB, MerKow RL,

13、 Templeman D (1990) Current concept review: the management of open fracture. J Bone Join Surg Am 72:290 15. Chapman MW, Mahoney M (1979) The role of early internal fixation in the management of open fracture. Clin Orthop Relat Res 138:120131 16. McKee MD, Yoo DJ, Zdero R, Dupere M, Wild L, Schemitsc

14、h EH, Mahoney J (2008) Combined single-stage osseous and soft tissue reconstruction of the tibia with the Ilizarov method and tissue transfer. J Orthop Trauma 22(3):183189 17. El Barbary H, Abdel Ghani H, Misbah H, Salem K (2005) Complex tibial plateau fractures treated with Ilizarov external fixato

15、r with or without minimal internal fixation. Int Orthop 29:182185 18. Ganocy K 2nd, Lindsey RW (1998) The management of civilian intraarticular gunshot wounds: treatment considerations and proposal of a classification system. Injury 29:SA1SA6 19. Shannon FJ, Mullett H, ORourke K (2002) Unreamed intr

16、amedullary nail versus external fixation in grade III open tibial fractures. J Trauma 52:650654References 20. Haidukewych GJ (2002) Temporary external fixation for the management of complex intra- and periarticular fractures of the lower extremity. J Orthop Trauma 16:678685 21. Panda M, Ntungila N,

17、Kalunda M, Hinsenkamp M (1998) Treatment of chronic osteomyelitis using the Papineau technique. Int Orthop 22:3740 22. Morykwas MJ, Argenta LC, Shelton-Brown EI, McGuirt W (1997) Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann PlastSurg

18、 38(6):553562 23. Philbeck TE Jr, Whittington KT, Millsap MH, Briones RB, Wight DG, Schroeder WJ (1999) The clinical and cost effectiveness of externally applied negative pressure wound therapy in the treatment of wounds in home healthcare Medicare patients. Ostomy Wound Manage 45(11):4150 24. Tang

19、AT, Ohri SK, Haw MP (2000) Novel application of vacuum assisted closure technique to the treatment of sternotomy wound infection. Eur J Cardiothorac Surg 17(4):482484References 25. Morykwas MJ, Argenta LC (1997) Nonsurgical modalities toenhance healing and care of soft tissue wounds. J South OrthopAssoc 6(4):279288 26. Fabian TS, Kaufman HJ, Lett ED, Thomas JB, Rawl DK, LewisPL, Summitt JB, Merryman JI, Schaeffer TD, Sargent LA, BurnsRP (2000) The evaluation of subatmospheric pressure andhyperbaric oxygen in ischemic full-thickness wound healing.Am Surg 66(12):11361143Research objec