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Lesson25About?Nanotechnology)
(第二十五課關(guān)于納米技術(shù))
Vocabulary(詞匯)ImportantSentences(重點(diǎn)句)QuestionsandAnswers(問(wèn)答)Problems(問(wèn)題)
Nanotechnologyisdefinedasfabricationofdeviceswithatomicormolecularscaleprecision.Deviceswithminimumfeaturesizeslessthan100nanometers(nm)areconsideredtobeproductsofnanotechnology.Ananometerisonebillionthofameter(10-9m)andistheunitoflengththatisgenerallymostappropriatefordescribingthesizeofsinglemolecules.Thenanoscalemarksthenebulousboundarybetweentheclassicalandquantummechanicalworlds;thus,realizationofnanotechnologypromisestobringrevolutionarycapabilities.Fabricationofnanomachines,nanoelectronicsandothernanodeviceswillundoubtedlysolveanenormousamountoftheproblemsfacedbymankindtoday.
Nanotechnologyiscurrentlyinaveryinfantilestage.However,wenowhavetheabilitytoorganizematterontheatomicscaleandtherearealreadynumerousproductsavailableasadirectresultofourrapidlyincreasingabilitytofabricateandcharacterizefeaturesizeslessthan100nm.Mirrorsthatdon’tfog,biomimeticpaintwithacontactanglenear180°,genechipsandfatsolublevitaminsinaqueousbeveragesaresomeofthefirstmanifestationsofnanotechnology.However,immenant
(imminent)breakthroughsincomputerscienceandmedicinewillbewheretherealpotentialofnanotechnologywillfirstbeachieved.[1]
Nanoscienceisaninterdisciplinaryfieldthatseekstobringaboutmaturenanotechnology.Focusingonthenanoscaleintersectionoffieldssuchasphysics,biology,engineering,chemistry,computerscienceandmore,nanoscienceisrapidlyexpanding.Nanotechnologycentersarepoppinguparoundtheworldasmorefundingisprovidedandnanotechnologymarketshareincreases.Therapidprogressisapparentbytheincreasingappearanceoftheprefix“nano”inscientificjournalsandthenews.Thus,asweincreaseourabilitytofabricatecomputerchipswithsmallerfeaturesandimproveourabilitytocurediseaseatthemolecularlevel,nanotechnologyishere.1ABriefHistoryofNanotechnology
Theamountofspaceavailabletousforinformationstorage(orotheruses)isenormous.Asfirstdescribedinalecturetitled,There’sPlentyofRoomattheBottomin1959byRichardP.Feynman,thereisnothingbesidesourclumsysizethatkeepsusfromusingthisspace.[2]Inhistime,itwasnotpossibleforustomanipulatesingleatomsormoleculesbecausetheywerefartoosmallforourtools.Thus,hisspeechwascompletelytheoreticalandseeminglyfantastic.Hedescribedhowthelawsofphysicsdonotlimitourabilitytomanipulatesingleatomsandmolecules.Instead,itwasourlackoftheappropriatemethodsfordoingso.However,hecorrectlypredictedthatthetimewouldcomeinwhichatomicallyprecisemanipulationofmatterwouldinevitablyarrive.
Prof.Feynmandescribedsuchatomicscalefabricationasabottom-upapproach,asopposedtothetop-downapproachthatweareaccustomedto.Thecurrenttop-downmethodformanufacturinginvolvestheconstructionofpartsthroughmethodssuchascutting,carvingandmolding.Usingthesemethods,wehavebeenabletofabricatearemarkablevarietyofmachineryandelectronicsdevices.However,thesizesatwhichwecanmakethesedevicesareseverelylimitedbyourabilitytocut,carveandmold.
Bottom-upmanufacturing,ontheotherhand,wouldprovidecomponentsmadeofsinglemolecules,whichareheldtogetherbycovalentforcesthatarefarstrongerthantheforcesthatholdtogethermacro-scalecomponents.Furthermore,theamountofinformationthatcouldbestoredindevicesbuildfromthebottom-upwouldbeenormous.
Sincethatinitialpreviewofnanotechnology,wehavedevelopedseveralmethodswhichprovethatProf.Feynmanwascorrectinhisprophesy.Themostnotablemethodsarescanningprobemicroscopyandthecorrespondingadvancementsinsupramolecularchemistry.Scanningprobemicroscopygivesustheabilitytopositionsingleatomsand/ormoleculesinthedesiredplaceexactlyasProf.Feynmanhadpredicted.AlthoughthelimitationsoftraditionalchemistrywerecriticizedinProf.Feynman’slectureduetoitsseeminglytediousandrandomnature,recentadvancementshaveimproveditspotentialusesfornanotechnology.2WhyMakeNanotechnology?
Onemightask,“whatexactlyarethepotentialusesofnanotechnology?”Inthelimitednumberofyearsthatnanotechnologyhasbeenconsideredpossible,aplethoraofanswerstothisquestionhavebeenpresented.Possibleanswersincludequantumcomputers,longtermlifepreservationandvirtuallyeverythinginbetween.Itseemsthatnanotechnologycouldpotentiallysolvejustaboutanyproblemthatwecouldthinkof;thus,amoreinterestingquestionis,“whatrealproblemswillnanotechnologysolvefirst?”Asofnow,itappearsthatthefirstrevolutionaryapplicationsofnanotechnologywillbeincomputerscienceandmedicine.Thesetwofieldswillmostlikelybeaffectedfirstsincetheybothcallformolecularscalemanipulationofmatterinthenearfuture.3SemiconductorFabrication
Moore’slaw,opticallithographyandthesearchforalternatives.
Computerchips(andthesiliconbasedtransistorswithinthem)arerapidlyshrinkingaccordingtoapredictableformula(byafactorof4every3years—Moore’sLaw).AccordingtotheSemiconductorIndustryAssociation’sextrapolationofformulassuchasthisone(SIAroadmap),itisexpectedthatthesizesofcircuitswithinourchipswillreachthesizeofonlyafewatomsinabout20years.
Sincealmostallofourmoderncomputersaremadefromsiliconsemiconductortransistorspatternedandcarvedbylight(photolithography),theshrinkingofcircuitspredictedbytheSIAmaynotbethemosteconomicalmethodforthefuture.Anenormousamountofmoneyhasbeeninvestedinthesemiconductorindustryinordertoconsistentlyshrinkandimproveoursemiconductorelectronics.Smallercircuitsrequirelessenergy,operatemorequicklyand,ofcourse,takeuplessspace.Thus,Moore’slawhasbeenadheredtosincecomputersfirstbecamecommerciallyavailable.However,thissimpleshrinkingofcomponentscannotcontinueformuchlonger.
AstransistorssuchastheMetal-OxideSemiconductorFieldEffectTransistor(MOSFET-oneoftheprimarycomponentsusedinintegratedcircuits)ismadesmaller,bothitspropertiesandmanufacturingexpensechangewiththescale.Currently,Ultravioletlightisusedtocreatethesiliconcircuitswithalateralresolutionaround200nm(thewavelengthofultravioletlight).Asthecircuitsshrinkbelow100nmnewfabricationmethodsmustbecreated,resultinginincreasingcosts.Furthermore,oncethecircuitsizereachesonlyafewnanometers,quantumeffectssuchastunnelingbegintobecomeimportant,whichdrasticallychangestheabilityforthecomputerstofunctionnormally.Thus,novelmethodsforcomputerchipfabricationhavebeenandarebeingintenselysoughtbymicrochipmanufactures.4MolecularandQuantumComputing
Alternativearchitecturesfornanocomputing
Inadditiontosingleelectrontransistors,twopromisingalternativestotraditionalcomputersaremolecularcomputingandquantumcomputing.Thesetwomethodsareintimatelyrelated,yetdealwithinformationontwodifferentlevels.Muchprogresshasbeenmadeintheseareasduringthelastyearsandbothhavebeenshowntobefeasiblereplacementsforsemiconductorchips.
Quantumcomputingseekstowriteprocessandreadinformationonthequantumlevel.Itisatthenanoscalethatquantummechanicaleffectssuchas(thewaveparticleduality)begintobecomeapparent.Numerousscientistsareseekingwaystostoreinformationwithinthequantummechanicalrealm.Thisisnotasimpletaskbecauseofthedelicatenatureofquantummechanicalsystems.However,sincethelawsofquantummechanicsinvolvesunintuitiveprinciplessuchassuperpositionandentanglement,aquantumcomputerwouldbeabletoviolatesomerulesthatlimitourclassicalcomputers.Forinstance,takingadvantageofsuperpositionwouldmeanthataquantumbitofinformation,termedaqubitwouldbeabletobeusedinseveralcomputationsatthesametime.Takingadvantageofentanglementwouldmeanthattheinformationcouldbeprocessedoverlongdistanceswithouttheclassicalrequirementofwires.[3]
Molecularcomputationisanothermethodcomplimentarytoquantumcomputingthatseekstowriteprocessandreadinformationwithinsinglemolecules.OnemoleculethathasprovedmostpromisingformolecularcomputationisDeoxyriboNucleicAcid(DNA).DNAisalongpolymermadeof4differentnucleotidesthatcanberepresentedbythelettersA,T,CandG.TheorderorsequenceofthesenucleotideswithinDNAprovidestheinformationformakingprotein,themaincomponentsofthemolecularscalemachineryusedbylivingorganismstocarryoutlifesustainingfunctions.
MathematicianshavefiguredoutnumerouswaystouseDNAandthevariousproteinsthatcomewithittocarryoutnumericalcomputationsthatarenotoriouslydifficultforsiliconcomputers,namelyNP-completeproblems.TheadvantagethatmolecularcomputingusingDNAhasoverconventionalcomputingisthatitismassivelyparallel.ThismeansthateachDNAmoleculecanfunctionasasingleprocessor,whichgreatlyimprovesthespeedofcomputationforcomplexproblems.5MedicalApplications
Molecularmedicine,bioinformaticsandbiomolecularnanotechnologyarerapidlyincreasingourabilitytohealandstayhealthy.
Theotherfieldinwhichmolecularscalemanipulationofmatterisreceivingabundantattentionismedicine.Sincealllivingorganismsarecomposedofmolecules,molecularbiologyhasbecometheprimaryfocusofbiotechnology.Countlessdiseaseshavebeencuredbyourabilitytosynthesizesmallmoleculescommonlyknowas‘drugs’thatinteractwiththeproteinmoleculesthatmakeupthemolecularmachinerythatkeepsusalive.OurunderstandingofhowproteinsinteractwithDNA,phospholipidsandotherbiologicalmoleculesiswhatallowssuchprogress.
Livingsystemsareabletolivebecauseofthevastamountofhighlyorderedmolecularmachineryfromwhichtheyarebuilt.ThecentraldogmaofmolecularbiologystatesthattheinformationrequiredtobuildalivingcellororganismisstoredintheDNA(whichwasdescribedaboveforitsuseinmolecularcomputation).ThisinformationistransferredfromtheDNAtotheproteinsbytheprocessescalledtranscriptionandtranslation.Theseprocessesareallexecutedbyvariousbiomolecularcomponents,mostlyproteinandnucleicacids.
Molecularbiologyisafieldinwhichthestudyoftheseinteractionshasledtothediscoveryofnumerouspharmaceuticalsthathavebeenenormouslyeffectiveincuringdisease.Understandingofmolecularmechanismsincludingsubstraterecognition,energyexpenditure,electrontransport,membraneactivityandmuchmorehavegreatlyimprovedourmedicaltechnology.
So,whatdoesthishavetodowithnanotechnology?Firstofallitshowstheabilitiesofmolecularscalemachinery.Sincethegoalofnanotechnologyismolecularandatomicprecision,nanotechnologyhasmuch(ifnoteverything)tolearnfromnature.Copying,borrowingandlearningtricksfromnatureisoneoftheprimarytechniquesusedbynanotechnologyandhasbeentermedbiomimetics.Secondly,ourabilitytodesignsynthetic,semi-syntheticandnaturalmolecularmachinerygivesusanenormouspotentialforcuringdiseaseandpreservinglife.AnextensivetextbooktitledNanomedicinehasbeenwrittenanddoesanexcellentjobofsummarizinghownanotechnologyischangingmedicine.6MolecularSimulation
Computermodelsofatoms,moleculesandnanostructuresprovidethetheorybehindnanoscience.
Finally,abranchofcomputersciencethatisallowingrapidprogresstobemadeinnanotechnologyisthecomputersimulationofmolecularscaleevents.Molecularsimulationisabletoprovideandpredictdataaboutmolecularsystemsthatwouldnormallyrequireenormousefforttoobtainphysically.Byorganizingvirtualatomsinamolecularsimulationenvironment,onecaneffectivelymodelnanoscalesystems.DeepakSrivastava,oneoftheworldsleadingexpertsinmolecularsimulationandcomputationalnanotechnology,hasdescribedthesituationwiththefollowingquote,
Currentlimitationsofmolecularsimulationtechniquesarethemolecularsimulationalgorithmandcomputationtimeforcomplexsystems.Forcefieldalgorithmsarecurrentlyquiteefficientandareoftenusedtoday.However,suchmodelsneglectelectronicpropertiesofthesystem.Inordertocalculateelectrondensity,quantummechanicalmodelsarerequired.However,asthenumberofatomsandelectronsisincreased,thecomputationalcomplexityofthemodelquicklyreachesthelimitsofourmostmodernsupercomputers.Thus,asthecomputationalabilitiesofourcomputersareimproved(oftenwithhelpfromnanoscience),increasinglycomplexsystemswillbewithinthereachofmolecularsimulation.7TheFuture
Nanotechnologyhasarrived,butithasyettorealizeitsfullpotential.
Ourcomputersarequitefastandsmall,butnorevolutionarybreakthroughincomputinghashappenedsincethetransistorwasinvented.Thehumangenomeprojecthasreachedcompletion,yetlimitsinourabilitytocurediseaseonamolecularbasisremain.Whileitisoftendifficulttopredictthefuture,somethingsseeminevitable.Justasaballthrownintotheaircanbeexpectedtofalltotheground,socanweexpectourtechnologytoreachthemolecularscale?
1.?nebulousadj.云霧狀的,星云的,朦朧的,模糊的。
2.?infantileadj.嬰兒(期)的,<貶>幼稚的,孩子氣的;嬰兒的。
3.?biomimeticn.【醫(yī)】擬生態(tài)的,仿生的。
4.?aqueous水的,aqueoushumor水狀體。
5.?manifestationn.顯示,表明,表示;(幽靈的)顯現(xiàn),顯靈。
6.?clumsyadj.笨拙的,笨重的;復(fù)雜難懂的,使用不便的;得罪人的,不得體的。Vocabulary
7.?covalentadj.共有原子價(jià)的,共價(jià)的。
8.?prophesyvt.預(yù)告;預(yù)言。
9.?plethoran.過(guò)多,過(guò)剩,過(guò)量。
10.?imminentadj.即將發(fā)生的,逼近的,臨近的。
11.?bringabout使(船)掉轉(zhuǎn)船頭,造成,引起〔導(dǎo)致〕(某事)。
12.fantasticadj.荒誕的,奇異的,古怪的;極大的,異乎尋常的;極出色的,了不起的。
13.?scanningprobemicroscopy掃描探針顯微鏡。
14.?entanglementn.瓜葛;牽連;糾纏;纏住。
15.?superpositionn.疊加。
16.?tunneln.地下通道,隧道,地道;(動(dòng)物棲息的)穴,洞穴通道vi.打通隧道。
17.?supramolecularchemistry超分子化學(xué)。
18.?photolithography光刻法,影印石版術(shù)。
19.?dogman.教義,教條;信條adj.教義的,教條的;信條的。
20.?transcriptionn.抄寫;標(biāo)音;抄本,副本,文字記錄,翻譯;按速記稿在打字機(jī)上打出文字;錄音,錄制。
21.?translationn.翻譯,譯本,譯文轉(zhuǎn)變;轉(zhuǎn)化。
22.?pharmaceuticaln.醫(yī)藥品。
23.?expendituren.花費(fèi),使用,((尤指金錢的)支出額、精力、時(shí)間、材料等的)耗費(fèi),消耗。
24.?membranen.(動(dòng)物或植物體內(nèi)的)薄膜,隔膜,膜,(植物的)細(xì)胞膜;(可起防水、防風(fēng)等作用的)膜狀物。
25.?biomimeticsn.仿生學(xué)。
[1]However,immenant(imminent)breakthroughsincomputerscienceandmedicinewillbewheretherealpotentialofnanotechnologywillfirstbeachieved.
然而,納米技術(shù)首先發(fā)揮其真正的潛力的地方是即將發(fā)生的在計(jì)算科學(xué)和醫(yī)藥領(lǐng)域的突破。ImportantSentences
[2]Theamountofspaceavailabletousforinformationstorage(orotheruses)isenormous.Asfirstdescribedinalecturetitled,‘There’sPlentyofRoomattheBottom’in1959byRichardP.Feynman,thereisnothingbesidesourclumsysizethatkeepsusfromusingthisspace.
我們可以利用的信息存儲(chǔ)(或者用做其他)空間是巨大的。正如RichardP.Feynman在1959年的名為“There’sPlentyofRoomattheBottom(在底層有大量的空間)”的講演中描述的,除了我們的體積笨重之外,沒(méi)有什么能阻止我們使用這些空間。
[3]However,sincethelawsofquantummechanicsinvolvesunintuitiveprinciplessuchassuperpositionandentanglement,aquantumcomputerwouldbeabletoviolatesomerulesthatlimitourclassicalcomputers.Forinstance,takingadvantageofsuperpositionwouldmeanthataquantumbitofinformation,termedaqubitwouldbeabletobeusedinseveralcomputationsatthesametime.Takingadvantageofentanglementwouldmeanthattheinformationcouldbeprocessedoverlongdistanceswithouttheclassicalrequirementofwires.
但是,由于量子力學(xué)包括一些不直觀的原理,比如疊加和糾纏,量子計(jì)算機(jī)可能違背某些限制經(jīng)典計(jì)算機(jī)的規(guī)則。例如,利用疊加原理,一個(gè)叫做qubit的量子比特信息可能同時(shí)用于幾個(gè)計(jì)算。利
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