Scutellarein-tetramethyl-ether-Standard-生命科學(xué)試劑-MCE

Hotline:400-820-3792Inhibitors?ScreeningLibraries?Proteinswww.MedChemEScutellareintetramethylether(Standard)Cat.No.:HY-N4314RCASNo.:1168-42-9分?式:C??H??O?分?量:342.34作?靶點:Bacterial;COX;NOSynthase;NF-κB作?通路:Anti-infection;Immunology/Inflammation;NF-κB儲存?式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY?物活性Scutellareintetramethylether(Standard)Scutellareintetramethylether的分析標(biāo)準(zhǔn)品。本產(chǎn)品?于研究及分析應(yīng)?。Scutellareintetramethylether(4',5,6,7-Tetramethoxyflavone)可以從Eupatoriumodoratum中得到的?物活性成分。Scutellareintetramethylether具有抗炎、抗、增強凝?和抗腫瘤的活性。Scutellareintetramethylether通過調(diào)節(jié)NF-κB通路發(fā)揮抗炎作?，并通過抑制外排泵來調(diào)節(jié)細(xì)耐藥性。此外，Scutellareintetramethylether通過內(nèi)性凝?途徑加速凝?時間。研究表明，Scutellareintetramethylether能有效抑制肝癌細(xì)胞系HepG2的?長(IC50=20.08μg/mL)。REFERENCES[1].PandithH,etal.EffectofSiamweedextractanditsbioactivecomponentscutellareintetramethyletheronanti-inflammatoryactivitythroughNF-κBpathway.JEthnopharmacol.2013May20;147(2):434-41.[2].MaiaGL,etal.FlavonoidsfromPraxelisclematideaR.M.KingandRobinsonmodulatebacterialdrugresistance.Molecules.2011Jun10;16(6):4828-35.[3].TriratanaT,etal.EffectofEupatoriumodoratumonbloodcoagulation.JMedAssocThai.1991May;74(5):283-7.[4].XianfengZhang,etal."DissectingtheantitumoreffectsofScutellariabarbata:Initialinsightsintothemetabolismofscutellarinandluteolinbygutmicrobiota."JournalofPharmaceuticalandBiomedicalAnalysis248(2024):116325.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;021-58955