生物化學(xué)與分子生物學(xué)（MBBS）智慧樹知到課后章節(jié)答案2023年下錦州醫(yī)科大學(xué)

生物化學(xué)與分子生物學(xué)（MBBS）智慧樹知到課后章節(jié)答案2023年下錦州醫(yī)科大學(xué)錦州醫(yī)科大學(xué)

緒論單元測試

Biochemistrycanbedividedintothreeprincipalareas,thatis：（）

A:thestructuralchemistryofthecomponentsoflivingmatterandrelationshipsofbiologicalfunctiontochemicalstructureB:metabolism,thetotalityofchemicalreactionsthatoccurinlivingmatterC:morphologychangeD:studyofstructureoftheHumanBodyE:geneticbiochemistry,thechemistryofprocessesandsubstancesthatstoreandtransmitbiologicalinformation

答案:thestructuralchemistryofthecomponentsoflivingmatterandrelationshipsofbiologicalfunctiontochemicalstructure;metabolism,thetotalityofchemicalreactionsthatoccurinlivingmatter;geneticbiochemistry,thechemistryofprocessesandsubstancesthatstoreandtransmitbiologicalinformation

第一章測試

Thenitrogencontentofoneproteinsampleis0.5g，andthentheproteincontentofitis：（）

A:1.565gB:6.25gC:1.25gD:12.5gE:3.125g

答案:3.125g

WhichofthefollowingsisbasicAA?（）

A:LysB:ProC:GluD:MetE:Tyr

答案:Lys

Whichofthefollowingaboutα-helixisnotcorrect：（）

A:thepeptidebondsarethemajorbondstostabilizethehelixB:thehelixisclockwiseC:thehelixisrighthandedD:3.6residuespercircleE:onepitchis0.54nm

答案:thepeptidebondsarethemajorbondstostabilizethehelix

OneAA(pI=5.6)willbenegativelychargedinasolution（）?

A:pH5.0B:pH4.7C:pH5.6D:pH8.6E:pH2.6

答案:pH8.6

Whichofthefollowingaboutproteindenaturaionisnotcorrect?（）

A:precipitatedproteinnotbesuretobedenatured(C)B:denaturedproteinmustprecipitateC:thephysico-chemicalpropertyofproteinchangedD:thesecondarybondofproteinarebrokenE:Thespatialstructureofproteinaredestroied

答案:denaturedproteinmustprecipitate

AllthecommonproeinabsorblightatawavelengthofUVcloseto（）nm?

A:200nmB:280nmC:300nmD:340nmE:260nm

答案:280nm

Theaminoacidfoundasconstituentsofmammalianproteinsareall()exceptforglycine?（）

A:D-β-AAB:L-β-AAC:L，D-α-AAD:L-α-AAE:D-α-AA

答案:L-α-AA

Whichofthefollowingaboutproteinsecondarystructureisnotcorrect?（）

A:itistherelativespatialpositionofskeletonatomonproteinmainchainB:aminoacidsequenceofproteinC:itislocalspatialstructureofonecertainpartofpeptidechaininproteinD:itdidnotinvolveintheconformationofsidechainofamnioacidE:itishydrogenbondthatmaintainthestabilityofproteinsecondarystructure

答案:aminoacidsequenceofprotein

Whichofthefollowingaboutquaternarystructueiscorrect?（）

A:alltheproteinhavequaternarystructureB:quaternarystructureofproteinwouldnotsuretobedestoriedC:thestabilityofproteinquaternarystructurewasmaintainedbydisulfidebondD:thesubunitwerepolymerizedbynoncovalentbondE:quaternarystructurewasessentialconditionformaintainingtheproteinbiologicalactivity

答案:thesubunitwerepolymerizedbynoncovalentbond

αhelixofproteinstructurebelongsto（）

A:secondarystructureB:domainC:tertiarystructureD:motifE:quaternarystructure

答案:secondarystructure

第二章測試

5’-endofthemajorityofmRNAineukaryoteshas（）

A:CCA-OHB:poly(A)tailC:initiationcodonD:stopcodonE:capsequence

答案:capsequence

WhichstatementisNOTtruefortRNA?（）

A:ThesecondarystructureoftRNAiscloverleafstructure.B:tRNAcontainsrarebases.C:VarioustRNAarepresentinthecell.D:tRNAisusuallycomposedof70-90nucleotides.E:AnticodonloopcontainstheanticodonthatiscomposedofthreebasesCCA.

答案:AnticodonloopcontainstheanticodonthatiscomposedofthreebasesCCA.

WhichstatementisNOTtrueforRNA?（）

A:tRNAcontainsmorerarebasesthanotherRNAs.B:RNAcontainsregionaldouble-strandedstructure.C:Itisusuallysingle-strandedmolecule.D:rRNAistheplaceforproteinsynthesis.E:mRNAcontainsthegeneticcodon.

答案:rRNAistheplaceforproteinsynthesis.

WhichstatementistrueforTm?（）

A:isusuallyRNAB:Higherpurityofnucleicacid,largerrangeofTmC:HigherGCcontent，higherTm.D:ThenucleicacidwithhigherE:HigherATcontent,higherTmF:Smallernucleicacid,largerrangeofTm.

答案:HigherGCcontent，higherTm.

ThesecondarystructureofDNAis（）

A:regionaldouble-strandedhelixB:supercoilC:double-strandedhelixD:polyAsequenceE:invertedLshape

答案:double-strandedhelix

ThetertiarystructureoftRNAis（）

A:polyAsequenceB:supercoilC:regionaldouble-strandedhelixD:double-strandedhelixE:invertedLshape

答案:invertedLshape

3'-endofmRNAhas（）

A:regionaldouble-strandedhelixB:invertedLshapeC:polyAsequenceD:double-strandedhelixE:supercoil

答案:polyAsequence

TheRNAthatcancarryaminoacidandtransferittoribosomeis（）

A:hnRNAB:rRNAC:mRNAD:siRNAE:tRNA

答案:tRNA

Thetemplateofproteinsynthesisis（）

A:hnRNAB:rRNAC:tRNAD:siRNAE:mRNA

答案:mRNA

DNAcanbeseparatedintotwosinglechainsduringheating（）

A:HybridizationB:DissociationofnucleicacidC:DNAdenaturationD:DNArenaturationE:Hydrolysisofnucleicacid

答案:DNAdenaturation

第三章測試

Whichoffollowingiscorrectaboutenzyme?（）

A:allenzymesareproteinsB:enzymesarebiocatalyststhatcatalyzethemultipledynamicprocessesinthebodyC:catalyticDNAandRNAarenotbiocatalystsD:enzymescannotbeupdatedinlivingtissueE:thesubstratesofenzymeareallorganiccompounds

答案:enzymesarebiocatalyststhatcatalyzethemultipledynamicprocessesinthebody

Whichoffollowingiscorrectaboutcharacterofenzyme?（）

A:alltheenzymescanacceleratetheratesofreactionsB:theenzymescatalyzethereactionswithhighefficiencyforitscoenzymeorprostheticgroupC:enzymesspeedupreactionbyelevatingtheactivationenergyD:enzymescanchangeequilibriumpointofreactionE:allgroupsinactivesitearetermedtheessentialgroups

答案:allgroupsinactivesitearetermedtheessentialgroups

Specificityofenzymerefersto：（）

A:differentclassificationofenzymesB:theabilityofanenzymetodiscriminatebetweentwocompetingsubstratesC:specificsitethatenzymeexistD:differentcatalyticmechanismE:enzymeshavehighlyspecificityforcoenzymes

答案:theabilityofanenzymetodiscriminatebetweentwocompetingsubstrates

Whichoffollowingisnotcorrectaboutactivesiteofanenzyme?（）

A:therearebindinggroupsandcatalyticgroupsinitB:allgroupsinactivesitearetermedtheessentialgroupsC:theenzymeswhichcatalyzethesamereactionhavethesameactivesiteD:itisformedbygroupsthatprimarystructureisclosetoeachotherinthepolypeptidesequenceE:itbindssubstrateandcatalyzesthereaction

答案:itisformedbygroupsthatprimarystructureisclosetoeachotherinthepolypeptidesequence

WhichoffollowingisnotcorrectaboutKm?（）

A:KmreflectsapproximatelytheaffinityofenzymetosubstrateB:KmisoneofthecharacteristicconstantsoftheenzymeC:KmisindependentofenzymeconcentrationD:KmisindependentofenzymestructureE:KmisequivalenttothesubstrateconcentrationatwhichVisequaltoVmax/2

答案:Kmisindependentofenzymestructure

Therelationshipbetweencompetitiveinhibitorandsubstrateisthattheyhave:（）

A:samemolecularweightB:similarstructureC:samephysico-chemicalpropertyD:samefunctionE:samesolubility

答案:similarstructure

Isoenzymesareenzymesthat：（）

A:havethesamephysiocochemicalpropertiesB:showthesameelectrophoreticmobilityC:havethesameimmunologicalpropertiesD:havethesamestructureE:catalyzethesamereaction

答案:catalyzethesamereaction

Whichoffollowingisnotcorrectaboutallostericenzyme?（）

A:itisknownasrate-limitingenzymeB:allostericeffectorbindstoactivesiteofenzymeC:allostericeffectorbindswithenzymereversiblyD:itcontainsmanysubunitsE:allostericeffectorbindswithenzymenoncovalently

答案:allostericeffectorbindstoactivesiteofenzyme

Whichoffollowingisnotcorrectaboutcovalentmodification?（）

A:enzymebindswithspecificchemicalgroupscovalentlyB:themostcommontypeisphosphorylationC:itconsumesATPD:itisafastregulationE:activityofenzymeincreasedafterphosphorylated

答案:activityofenzymeincreasedafterphosphorylated

WhichoffollowingisnotcorrectaboutLDHisoenzymes?（）

A:twosubunitsareproductsofdifferentgenesB:havethesameKmtothesamesubstrateC:containsHandMsubunitsD:differentisoenzymesshowsacharacteristicelectrophoreticmobilityE:LDHhasfivedifferentisoenzymes

答案:havethesameKmtothesamesubstrate

第四章測試

Theend-productofglycolysisis:（）

A:pyruvateB:acetyl-CoAC:oxaloacetateD:lactateE:uricacid

答案:lactate

Thekeyenzymeoftheglycolysisis:（）

A:pyruvatekinaseB:fructose1,6-bisphophataseC:pyruvatedehydrogenaseD:pyruvatecarboxylaseE:LDH

答案:pyruvatedehydrogenase

Whyerythrocytesmetabolizeglucosebyanaerobicglycolysis?（）

A:absenceofTPPB:lackofmitochondriaC:absenceofoxygenD:lackofmicrosomeE:absenceofcoenzymeA

答案:lackofmitochondria

1moleculeofpyruvatewhichisoxidizedcompletelymaygenerate()moleculesofATP.（）

A:19B:14or15C:20D:12.5E:21

答案:12.5

Substrate-levelphosphorylationincitrateacidcycleis:（）

A:citrate→α－ketoglutarateB:succinyl-CoA→succinateC:succinate→fumarateD:fumarate→malateE:malate→oxaloacetate

答案:succinyl-CoA→succinate

Whichoffollowingisnotthekeyenzymeinaerobicoxidationofcarbohydrate?（）

A:citratesynthaseB:isocitratedehydrogenaseC:succinatedehydrogenaseD:a－ketoglutaratedehydrogenasecomplexE:pyruvatedehydrogenasecomplex

答案:succinatedehydrogenase

HowmanyATPsareproducedbytheoxidationofamoleculeofaceylCoAviathecitricacidcycle?

A:12B:11C:9D:13E:10

答案:13

WhichoffollowinggenerateFADH2afterdehydrogenation?（）

A:acetoacetateB:fumarateC:succinateD:malateE:oxaloacetate

答案:succinate

Whatarethemostimportantproductsthecellsgeneratebymeansofthepentosephosphatepathway?（）

A:ribulose-1,5-biophosphateandNADPHB:NADP+andribose-5-phosphateC:lactateandATPD:NADPHandUDP-riboseE:ribose-5-phosphateandNADPH

答案:ribose-5-phosphateandNADPH

Whichismetabolizedthroughboththeglycolyticpathwayandthepentosephosphatepathway?（）

A:glucose1-phosphateB:glucose6-phosphateC:fructose1,6-bisphophateD:fructose6-phosphateE:ribose5-phosphate

答案:glucose6-phosphate

第五章測試

Whichofthefollowingmetabolicprocessiscompletedinmitochondriontotally（）

A:petosephosphatepathwayB:aerobicoxidationC:glycogenesisD:gluconeogenesisE:oxidativephosphorylation

答案:oxidativephosphorylation

Whichofthefollowingisthemostimportantelementintheregulationofoxidativephosphorylation?（）

A:O2B:Cytaa3C:NADHD:FADH2E:［ADP］/［ATP]

答案:［ADP］/［ATP]

WhichagentisaninhibitorofelectrontransportatComplexⅢ?（）

A:DNPB:antimycinAC:amobarbitalD:rotenoneE:piericidinA

答案:antimycinA

Whichofthefollowingisnottheenergy-richcompound?（）

A:creatinephosphateB:PEPC:ATPD:2,3-bisphoglycerateE:1,3-bisphoglycerate

答案:2,3-bisphoglycerate

WhichoffollowingisthecarrierofNADHfromcytosoltomitchondria?（）

A:malateB:aspartateC:α-ketoglutarateD:oxaloacetateE:carnitine

答案:malate

Thecoenzymeofα-glycerophosphatedehydrogenaseinmitochondriais:（）

A:FMNB:NADP+C:FADD:NAD+E:HSCoA

答案:FAD

HowmanyATPswillbeproducedwhen1cytosolicNADHistransportedintothemitochondriabyα-glycerophosphateshuttle?（）

A:5B:1C:2.5D:1.5E:4

答案:1.5

WhichofthefollowingenzymeusesFADasprotheticgroup?（）

A:α-ketoglutaratedehydrogenasecomplexB:malatedehydrogenaseC:isocitratedehydrogenaseD:succinatedehydrogenaseE:lactatedehydrogenase

答案:succinatedehydrogenase

Thecharacteristicofbiologicaloxidationis（）

A:notregulatedbycircumstanceB:directcombinationofhydrogenandoxygentoformwaterC:nonenzymaticreactionD:energyreleasedgraduallyandhighavailabilityE:takenplacemainlyincytosol

答案:energyreleasedgraduallyandhighavailability

TheorderofNADHrespiratorychainis:（）

A:NAD+→complexⅡ→complexⅠ→CoQ→complexⅢB:NAD+→complexⅡ→CoQ→complexⅢC:NAD+→complexⅠ→CoQ→complexⅡ→complexⅢD:NAD+→complexⅠ→complexⅡ→CoQ→complexⅢE:NAD+→complexⅠ→CoQ→complexⅢ

答案:NAD+→complexⅠ→CoQ→complexⅢ

第六章測試

NADPHinfattyacidsynthesiscomesfrom:（）

A:aerobicoxidationofglucoseB:glucuronatepathwayC:gluconeogenesisD:glycolysisE:pentosephosphatepathway

答案:pentosephosphatepathway

HowmanymolsofATPareyieldedwhen1molstearicacid(18C)isoxidizedtoCO2andH2O?（）

A:120B:165C:131D:182E:199

答案:120

Whichisnotrequiredinβ-Oxidationoffattyacids?（）

A:NADP+B:carnitineC:CoASHD:FADE:NAD+

答案:NADP+

Whichoffollowingdoesnotutilizeketonebodies?（）

A:liverB:skeletalmuscleC:brainD:heartE:kindey

答案:liver

Cholineisactivatedintheformof（）,beforeitentersdiacylglycerolpathway.

A:GDP-cholineB:ADP-cholineC:CDP-cholineD:UDP-cholineE:CMP-choline

答案:CDP-choline

Intheliver,（）istherate–limitingenzymeonthepathwayforsynthesisofcholesterol.

A:ACATB:HMGCoAreductaseC:HSLD:LCATE:HMGCoAsynthase

答案:HMGCoAreductase

ThemajorfunctionofHDLis（）

A:totransportfreefattyacidB:totransportendogenousTGfromtheintestinetothetissuesC:totransportendogenousfromcholesterolthelivertothetissuesD:tocarryexogenousTGandCEfromtheintestinetothetissuesE:reversecholesteroltransport

答案:reversecholesteroltransport

WhichisthemajorformthattransportsendogenousTAGsfromthelivertothetissues?（）

A:IDLB:CMC:LDLD:HDLE:VLDL

答案:VLDL

Thelipoproteinthattransferendogenouscholesterolis:（）

A:VLDLB:HDLC:LDLD:IDLE:CM

答案:LDL

WhichisthemajorformthattransportsexogenousTAGstothecirculation?（）

A:HDLB:LDLC:VLDLD:IDLE:CM

答案:CM

第七章測試

WhichofthefollowingisnotproducedbyTyr?（）

A:epinephrineB:norepinephrineC:dopamineD:PheE:melanin

答案:Phe

Whichofthefollowingisthestorageandtransportationstyleofammonia?（）

A:GlnB:AsnC:GluD:TyrE:GSH

答案:Gln

Whichofthefollowingisnottheoutletofα-ketoacidthatproducedbydeaminationofaminoacid?（）

A:beconvertedtoessentialamminoacidB:beconvertedtoglucoseandketonbodiesC:giverisetoCO2andH2OD:beconvertedtoglucoseE:beconvertedtoketonbodies

答案:beconvertedtoessentialamminoacid

Whichofthefollowingisthecarrierofonecarbonunit?（）

A:SAMB:FH4C:FH2D:biotinE:folicacid

答案:FH4

WhichofthefollowingaminoacidcanproducePAPS?（）

A:glutamateB:taurineC:homocysteineD:cysteineE:methionine

答案:cysteine

WhichofthefollowingisthedirectdonorofCH3?（）

A:N5,N10-CH2-FH4B:FADC:SAMD:N5,N10=CH-FH4E:N5-CH3-FH4

答案:SAM

Inthesynthesisofurea,oneNcomefromNH3,anotherNcomefrom（）directly?

A:AspB:ProC:GluD:PheE:Lys

答案:Asp

Intheprocessofureacycle,whichofthefollowingsubstancecangooutmitochondrion?（）

A:ornithineB:argininosuccinicacidC:arginineD:carbomoylphosphateE:citrulline

答案:citrulline

Whichofthefollowingisnotonecarbonunit?（）

A:CH3B:CH2C:CHD:CO2E:CHO

答案:CO2

Whichofthefollowingisonlyketogenicaminoacid?（）

A:GlycineB:IsoleucineC:ThreonineD:TyrosineE:Leucine

答案:Leucine

第八章測試

Whichofthefollowingisfirstsynthesizedintheprocessofdenovosynthesisofpurinenucleotide?（）

A:IMPB:AMPC:ATPD:GTPE:GMP

答案:IMP

Whichofthefollowingistheendproductionofpurinenucleotidecatabolicmetabolism?（）

A:uricacidB:β-alanineC:ureaD:creatineE:creatinine

答案:uricacid

WhichofthefollowingisthemethylgroupdonorofTMP?（）

A:N5-CH3-FH4B:N5，N10-CH2-FH4C:N10-CHO-FH4D:N5，N10=CH-FH4E:N5-CH=NH-FH4

答案:N5，N10-CH2-FH4

Whichofthefollowingistheenzymethatcatalyzethesynthesisofuricacid?（）

A:adenosinedeaminaseB:xanthineoxidaseC:urateoxidaseD:GuanosinedeaminaseE:nucleophosphatase

答案:xanthineoxidase

Whichofthefollowingsubstancedirectlylinknucleotidesynthesisandglucosemetabolism?（）

A:glucoseB:glucose-1,6-diphosphateC:glucose-1-phosphateD:ribose-5-phosphateE:glucose-6-phosphate

答案:glucose-6-phosphate

Whichofthefollowingisnotthedirectmaterialofdenovosynthesisofpurinenucleotide?（）

A:aspartateB:glutamateC:glycineD:onecarbonunitE:CO2

答案:glutamate

Whichofthefollowingisdirectlyreduced,andproducedeoxynucleotide?（）

A:NTPB:ribonucleosideC:riboseD:NMPE:NDP

答案:NDP

Whichofthefollowingistheanalogueofazaserine?（）

A:aspartateB:glutamineC:serineD:glycineE:asparagine

答案:glutamine

WhichofthefollowingmaterialcouldprovideC4andC5forpurinering?（）

A:GlycineB:glutamateC:alanineD:glutamineE:aspartate

答案:Glycine

Whichofthefollowingisthecommonmaterialforthesynthesisofpyrimidineandpurinenucleotide?（）

A:folicacidB:fumarateC:glutamineD:glycineE:asparagine

答案:glutamine

第九章測試

Whichofthefollowingisnotthedonatorofbiotransformation?（）

A:UDPGAB:PAPSC:SAMD:acetylCoAE:UDPG

答案:UDPG

Whichofthefollowingcanprovideactivemethylgroup?（）

A:GlyB:UDPGAC:PAPSD:NADPHE:SAM

答案:SAM

Whichofthefollowingcanprovideactivesulphate?（）

A:SAMB:GlyC:PAPSD:NADPHE:UDPGA

答案:PAPS

ThemostimportantphaseIreactionofthebiotransformationis（）

A:syntheticreactionB:reductionreactionC:decarboxylationreactionD:oxidationreactionE:hydrolysisreaction

答案:oxidationreaction

Themostrelevantofthebiotransformationprocessinliveris（）

A:peroxidaseB:catalaseC:oxygendehydrogenaseD:oxygenatomE:cytochromeP450

答案:cytochromeP450

Non-nutritionalsubstancecan（）afterbiotransformation.

A:decreasethetoxicityB:excretefromthebileacidorurineC:increasethewatersolubilityD:decreasethedrugactivityE:increaselipidesolubility

答案:decreasethetoxicity;excretefromthebileacidorurine;increasethewatersolubility;decreasethedrugactivity

Thecommondonorsoftheconjugatedsubstancesare（）inthephaseIIreactionoftheliver.

A:SAMB:acetylCoAC:PAPSD:UDPGE:UDPGA

答案:SAM;acetylCoA;PAPS;UDPGA

ThemostimportantphaseIIreactioninthebiotransformationis（）.

A:combinewithanacylgroupB:combinewithglutathioneC:combinewithglucuronicacidD:combinewithmethylgroupE:combinewithsulphuricacid

答案:combinewithglucuronicacid

Whichisthemostimportantenzymetakingpartintheoxidationreactionofthebiotransformation?（）

A:amineoxidaseB:alcoholdehydrogenaseC:dioxygenaseD:hydrolaseE:monooxygenase

答案:monooxygenase

Themostsignificanceofthebiotransformationisto（）.

A:increasethebioactivityorthetoxicityofthedrugB:detoxicateC:provideenergyD:inactivebioactivesubstancesE:increasethesolubilityofthenon-nutritionalsubstanceandeliminatefromthebody

答案:increasethesolubilityofthenon-nutritionalsubstanceandeliminatefromthebody

第十章測試

DNAandRNAarecomposedoffourtypesofdeoxyribonucleotidesandribonucleotides,respectivelylinkedwith（）?

A:peptidebondsB:disulfidebondsC:3’,5’-phosphodiesterD:hydrogenbondsE:saltbonds

答案:3’,5’-phosphodiester

TheprokaryoticDNA-polcoreenzymeismadeupwith（）?

A:αεθB:αβγC:αβεD:noneoftheaboveE:α2ββ’γ

答案:αεθ

IntheprokaryoticDNAreplication,whichofthefollowingisNOTneeded?（）

A:DnaAB:DnaGC:DnaBD:PCNAE:SSB

答案:PCNA

WhichoftheseenzymeisnotconcernedwithDNAreplication？（）

A:RNAdependentDNApolymeraseB:DNAligaseC:topoisomeraseD:DNAdependentDNApolymeraseE:DNAdependentRNApolymerase

答案:RNAdependentDNApolymerase

IntheinitiationofDNAreplication,theproperorderthatfollowingenzymeandproteinactingis?1,DNA-polⅢ2，SSB3，primase4,helicase（）

A:2,3,4,1B:1,2,3,4C:1,4,2,3D:3,1,2,4E:4,2,3,1

答案:4,2,3,1

Whichofthefollowingcouldproofreading,DNArepairing,fillingofgaps?（）

A:DNApolδB:DNApolγC:DNApolⅢD:DNApolⅠE:DNApolα

答案:DNApolⅠ

WhichofthefollowingserveastheenzymeinmitochondriaDNAreplication?（）

A:DNApolδB:DNApolⅠC:DNApolγD:DNApolαE:DNApolⅢ

答案:DNApolγ

InDNAreplication,whatisthereasonofOkazakifragmentgenerated?（）

A:thedirectionofreplicationisdifferentwiththedirectionofunwindingB:comefromprimerC:DNAbecoiledandtiedknotsinreplicationD:thespeedofDNAreplicationistoofastE:bidirectionalreplication

答案:thedirectionofreplicationisdifferentwiththedirectionofunwinding

ThematerialsofDNAsynthesisare：（）

A:dATP，dGTP，dCTP，dTTPB:dADP，dGDP，dCDP，dTDPC:dAMP，dGMP，dCMP，dTMPD:ATP，GTP，CTP，UTPE:AMP，GMP，CMP，UMP

答案:dATP，dGTP，dCTP，dTTP

Whichofthefollowingistheproductofthereplicationdiscontinuously?（）

A:RNAB:KlenowfragmentC:OkazakifragmentD:leadingstrandE:primer

答案:Okazakifragment

WhichofthefollowingisthelargerfragmentofDNApolⅠ?（）

A:OkazakifragmentB:KlenowfragmentC:laggingstrandD:primerE:leadingstrand

答案:Klenowfragment

第十一章測試

Whichoneiscorrectabouttheexon?（）

A:SplicingistheprocessthatcanremovetheexonsB:TheDNAsequencethatistranscribedbutnottranslatedC:TheDNAsequencethatistranscribedandtranslatedD:NoncodingregionE:TheDNAsequencethatisnottranscribed

答案:TheDNAsequencethatistranscribedandtranslated

ThetranscriptofRNApolymeraseIineukaryotesis（）

A:45SrRNAB:tRNAC:miRNAD:snRNAE:hnRNA

答案:45SrRNA

TheprimaryroleofRNApolymeraseⅢistosynthesis（）

A:lncRNAB:tRNAand5SrRNAC:45SrRNAD:hnRNAE:snRNA

答案:tRNAand5SrRNA

WhichonecaninhibitprokaryoticRNApolymerasespecifically?（）

A:AmanitinB:RifampicinC:NitronicsaltD:PseudouridineE:Chloromycetin

答案:Rifampicin

RNAholoenzymeincludesσsubunit,itbindswithDNAtemplatestrandattheinitiationofthetranscription.Intheelongationstage，theσsubunitwill（）

A:servethefunctionasterminationfactor.B:bindtothetemplatestrandloosely.C:movewithholoenzymeonDNAstrandD:intheelongationstage,theconformationwillbechanged.E:dissociatefromtheholoenzymeintheelongationstage.

答案:dissociatefromtheholoenzymeintheelongationstage.

Feather-likestructureoftranscriptionunderelectronmicroscopeindicates（）

A:translationwasinitiatedbeforethetranscriptiontermination.B:double-strandtemplatemeltedtosinglestrands.C:severalinitiationsitesinthetranscriptionD:formationofpolysomeappearsafterthetranscription.E:transcriptionproductRNAandtemplateDNAcanformlongheterodoublestrand.

答案:translationwasinitiatedbeforethetranscriptiontermination.

ThebindingsiteofTFⅡDis（）

A:PribnowboxB:GCboxC:CAATboxD:TATAboxE:CCAATbox

答案:TATAbox

第十二章測試

WhichofthefollowingmaterialcancarrythegeneticinformationofDNAtothecytoplasmandtoguidethebiosynthesisofprotein（）。

A:mRNAB:DNAC:exonD:tRNAE:rRNA

答案:mRNA

Inthecharacteristicsofthecodons,theframeshiftmutationisrelatedto（）。

A:degeneracyB:wobbleC:directionD:universalityE:non-punctuationandnonoverlapping

答案:non-punctuationandnonoverlapping

Aminoacyl-tRNAsynthetasehasspecificityfor（）。

A:ATPB:GTPC:tRNAonlyD:aminoacidandtRNAE:aminoacidonly

答案:aminoacidandtRNA

WhichofthefollowingtRNAanticodonismatchedwithmRNAcodonACG（）。

A:UGCB:CGUC:CGTD:GCAE:TGC

答案:CGU

Theintroductionofeukaryoticsecretoryproteinsintotheendoplasmicreticulumis（）。

A:molecularchaperoneB:EFC:RFD:IFE:signalpeptide

答案:signalpeptide

Thesubstancethatisnotneededforproteinbiosynthesisis（）。

A:DNAB:mRNAC:multipleproteinfactorsD:aminoacidsE:ribosome

答案:DNA

Whichenzymecatalyzestheformationofpeptidebond（）。

A:aminoacyl-tRNAsynthetaseB:translocaseC:transpeptidaseD:proteindisulfideisomeraseE:peptideprolylcis-transisomerase

答案:transpeptidase

Theenergyrequiredforpeptidechainelongationinprokaryoticproteinbiosynthesisis（）。

A:ATPB:GTPC:UTPD:CTPE:GDP

答案:GTP

Substancesinvolvedinproteinbiosynthesisare（）。

A:mRNAB:aminoacidC:tRNAD:GTPE:ATP

答案:mRNA;aminoacid;tRNA;GTP;ATP

Whatcomponentsareneededfortheribosomecycle（）。

A:aminoacyl-tRNAB:mRNAC:ribosomeD:elongationfactorE:GTP

答案:aminoacyl-tRNA;mRNA;ribosome;elongationfactor;GTP

第十三章測試

Thegeneralregulatorypointofgeneexpressionis（）。

A:geneactivationB:post-transcriptionalprocessingC:transcriptioninitiationD:translationinitiationE:post-translationalprocessing

答案:transcriptioninitiation

Whichofthefollowingdoesnotbelongtogeneexpression（）。

A:ThetranslationofmRNAintoproteinB:ThetranscriptionofrRNAC:ThereplicationofRNAD:ThetranscriptionofmRNAE:ThetranscriptionoftRNA

答案:ThereplicationofRNA

Operonsdonotinclude（）。

A:regulatorysequenceB:operatorC:trans-actingfactorD:promoterE:structuralgene

答案:trans-actingfactor

WhichisboundbyRNApolymeraseandinitiatestranscription（）。

A:silencerB:enhancerC:promoterD:operonE:attenuator

答案:promoter

Whichinducesthetranscriptionoflacoperon（）。

A:fructoseB:lactoseC:allolactoseD:arabinoseE:glucose

答案:allolactose

WhichofthefollowinggeneraltranscriptionfactorscanrecognizeandbindtoTATAboxdirectly（）。

A:TFⅡDB:TFⅡAC:TFⅡED:TFⅡFE:TFⅡB

答案:TFⅡD

Whichofthefollowingbelongstoacis-actingelement（）。

A:enhancerB:ρfactorC:transcriptionalrepressorD:transcriptionalactivatorE:σfactor

答案:enhancer

Whichofthefollowingbelongstoatrans-actingfactor（）。

A:operatorB:elongationfactorC:transcriptionfactorD:promotorE:enhancer

答案:transcriptionfactor

Thestructureoflacoperonconsistof（）。

A:oneoperatorB:IgeneC:oneenhancerD:onepromoterE:threestructuralgenes

答案:oneoperator;Igene;onepromoter;threestructuralgenes

Whenthetryptophanlevelsarehigh,thetryptophanoperonisregulatedby（）。

A:negativeregulationB:attenuatorC:repressorproteinD:positiveregulationE:cAMP-CAPcomplex

答案:negativeregulation;attenuator;repressorprotein

第十四章測試

Whichofthefollowingdoesnotbelongtosecondmessenger（）。

A:cGMPB:DAGC:IP3

D:PIP2E:cAMP

答案:PIP2

Whichofthefollowingdonotparticipateincellularsignaltransduction（）。

A:NOB:NAD+C:insulinD:Ca2+E:Ach

答案:NAD+

Thechemicalnatureofintracellularreceptorsis（）。

A:glycolipidB:DNAbindingproteinC:lipoproteinD:glycoproteinE:Gprotein

答案:DNAbindingprotein

Whichofthefollowingaboutpropertiesofbindingofhormoneandreceptorisnotcorrect（）。

A:highspecificityB:covalentbondingC:specifiedmodeofactionD:highaffinityE:saturability

答案:covalentbonding

Gproteinisreferredto（）。

A:guanylatecyclaseB:PKAC:GRB2bindingproteinD:GTPbindingproteinE:PKG

答案:GTPbindingprotein

WhichofthefollowingdoesnotparticipateinAC-cAMP-PKApathway（）。

A:receptorB:ACC:ligandD:GProteinE:cGMP

答案:cGMP

TheαsubunitofGproteinhavetheactivityof（）。

A:CTPaseB:GTPaseC:TTPaseD:ATPaseE:UTPase