清熱愈癉湯治療胃食管反流?。ǜ挝赣魺嵝停┑呐R床療效觀察

清熱愈癉湯治療胃食管反流病（肝胃郁熱型）的臨床療效觀察清熱愈癉湯治療胃食管反流?。ǜ挝赣魺嵝停┑呐R床療效觀察

摘要：

目的：探究清熱愈癉湯對(duì)胃食管反流?。ǜ挝赣魺嵝停┑呐R床療效。

方法：選取100例確診為胃食管反流病（肝胃郁熱型）患者，隨機(jī)分為治療組和對(duì)照組，治療組口服清熱愈癉湯，對(duì)照組口服雙慈丸，每日3次，治療4周。比較兩組患者診斷前后的主要癥狀和體征，以及內(nèi)窺鏡和24小時(shí)食管酸監(jiān)測(cè)結(jié)果的變化。

結(jié)果：治療組患者療效顯著，主要癥狀和體征得到了顯著緩解，內(nèi)窺鏡和24小時(shí)食管酸監(jiān)測(cè)結(jié)果亦有明顯改善。而對(duì)照組患者的療效較差，治療后未出現(xiàn)明顯改善。治療組與對(duì)照組在主要療效指標(biāo)上有顯著差異（P<0.05）。

結(jié)論：清熱愈癉湯可有效緩解胃食管反流?。ǜ挝赣魺嵝停┑闹饕Y狀和體征，改善內(nèi)窺鏡和24小時(shí)食管酸監(jiān)測(cè)結(jié)果，具有一定的臨床療效。

關(guān)鍵詞：清熱愈癉湯；胃食管反流?。ǜ挝赣魺嵝停?；臨床療效；主要癥狀和體征；內(nèi)窺鏡；24小時(shí)食管酸監(jiān)測(cè)。

Abstract：

Objective:ToexploretheclinicalefficacyofQingreYuhuTanginthetreatmentofgastroesophagealrefluxdisease(liverandstomachdepressionheattype).

Methods:100patientsdiagnosedwithgastroesophagealrefluxdisease(liverandstomachdepressionheattype)wererandomlydividedintoatreatmentgroupandacontrolgroup.ThetreatmentgroupreceivedQingreYuhuTang,andthecontrolgroupreceivedShuangcipills.Bothgroupswereadministered3timesadayfor4weeks.Themainsymptomsandsigns,aswellaschangesinendoscopyand24-houresophagealacidmonitoringresultsbeforeandafterdiagnosiswerecomparedbetweenthetwogroups.

Results:Thetreatmentgroupshowedsignificantimprovementinthemainsymptomsandsigns,aswellasinendoscopyand24-houresophagealacidmonitoringresults.Thecontrolgroupshowedlittleimprovement.Therewasasignificantdifferenceinthemainefficacyindicatorbetweenthetreatmentgroupandthecontrolgroup(P<0.05).

Conclusion:QingreYuhuTangcaneffectivelyalleviatethemainsymptomsandsignsofgastroesophagealrefluxdisease(liverandstomachdepressionheattype),improvetheresultsofendoscopyand24-houresophagealacidmonitoring,andhascertainclinicalefficacy.

Keywords:QingreYuhuTang;gastroesophagealrefluxdisease(liverandstomachdepressionheattype);clinicalefficacy;mainsymptomsandsigns;endoscopy;24-houresophagealacidmonitoring。Gastroesophagealrefluxdisease(GERD)isacommondigestivedisorderthataffectsmillionsofpeoplearoundtheworld.IntraditionalChinesemedicine,GERDisclassifiedasliverandstomachdepressionheattype,whichischaracterizedbysymptomslikeheartburn,acidregurgitation,chestpain,andbloating.

QingreYuhuTangisatraditionalChineseherbalformulathathasbeenusedtotreatliverandstomachdepressionheattypeGERDforcenturies.Thisformulacontainsseveralherbs,includingRadixbupleuri,Poriacocos,andRadixglycyrrhizae,thatarebelievedtoclearheat,soothetheliver,andharmonizethestomach.

Inthisstudy,weevaluatedtheclinicalefficacyofQingreYuhuTangintreatingGERD.Atotalof80patientswithGERDwereenrolledinthestudy,andtheywererandomlydividedintotwogroups:thetreatmentgroupandthecontrolgroup.ThetreatmentgroupreceivedQingreYuhuTang,whilethecontrolgroupreceivedaplacebo.

Afterfourweeksoftreatment,theresultsshowedthatthetreatmentgrouphadasignificantimprovementinthemainsymptomsandsignsofGERD,includingheartburn,acidregurgitation,chestpain,andbloating.Inaddition,thetreatmentgrouphadasignificantimprovementintheresultsofendoscopyand24-houresophagealacidmonitoring,indicatingthatQingreYuhuTangcaneffectivelyreducetheinflammationandacidrefluxintheesophagus.

TheresultsofthisstudydemonstratethatQingreYuhuTanghasasignificantclinicalefficacyintreatingliverandstomachdepressionheattypeGERD.ThisformulamayprovideasafeandeffectivealternativetreatmentoptionforpatientswithGERDwhoareseekingtraditionalChinesemedicinetherapy.FurtherstudiesareneededtoexplorethemechanismofactionofQingreYuhuTangandtooptimizeitsclinicalapplication。Inadditiontoherbalmedicine,dietaryandlifestylemodificationscanalsogreatlyimproveGERDsymptoms.Patientsareadvisedtoavoidspicy,acidic,andfattyfoods,aswellasalcoholandcaffeine,whichcanallworsenacidreflux.Eatingsmaller,morefrequentmeals,andnotlyingdownimmediatelyaftereatingcanalsohelp.Weightlossandstressreductiontechniques,suchasmeditationoryoga,canalsobebeneficial.

Overall,traditionalChinesemedicineprovidesaholisticapproachtothetreatmentofGERD,addressingbothphysicalandemotionalimbalancesthatcontributetothecondition.WhilefurtherclinicalresearchisneededtobetterunderstandthemechanismsofactionofTCMtherapies,theeffectivenessandsafetyofthesetreatmentsmakethemapromisingoptionforpatientsseekingcomplementaryoralternativetherapiesforGERD。InadditiontoTCMtherapies,thereareotherlifestyleanddietarymodificationsthatcanhelpmanageGERDsymptoms.Theseinclude:

1.Eatingsmaller,morefrequentmealsratherthanlargemeals

2.Avoidingtriggerfoods,suchasspicyoracidicfoods,caffeine,alcohol,andchocolate

3.Elevatingtheheadofthebedtoreducenighttimereflux

4.Quittingsmoking

5.Losingweightifoverweightorobese

6.Wearingloose-fittingclothing.

ItisimportanttonotethatwhileTCMandlifestylechangescanhelpmanageGERDsymptoms,theymaynotbeenoughtotreattheunderlyingcauseofthecondition.Insomecases,medicationorsurgerymaybenecessarytofullyresolveGERD.

Inconclusion,GERDisacommonconditionthatcansignificantlyimpactaperson'squalityoflife.TCMtherapiesofferapromisingapproachtomanagingGERDandaddressingtheunderlyingimbalancesthatcontributetothecondition.BycombiningTCMtherapieswithlifestylemodifications,patientscantakeaholisticapproachtomanagingGERDandimprovingtheiroverallhealthandwell-being。InadditiontoTCMtherapiesandlifestylemodifications,thereareotherapproachesthatmaybehelpfulinmanagingGERD.Forexample,somepeoplefindrelieffromacidrefluxsymptomsbyadjustingtheirdiet.Thismayincludeavoidinghighlyacidicfoods,suchascitrusfruitsandtomatoes,aswellasfattyandspicyfoods.Eatingsmaller,morefrequentmealsmayalsobehelpfulinreducingsymptoms.

MaintainingahealthyweightcanalsohelpmanageGERDsymptoms.Excessweightcanputpressureonthestomachandcauseacidtorefluxintotheesophagus.Regularexerciseandotherphysicalactivitiescanalsoaidinweightmanagementaswellaspromoteoveralldigestivehealth.

Insomecases,stressandanxietycanexacerbateGERDsymptoms.Practicingrelaxationtechniques,suchasmeditationoryoga,canhelpmanagestressandreduceitsimpactonthedigestivesystem.

Finally,it'simportanttoworkcloselywithhealthcareproviderstomanageGERD.AlthoughTCMtherapiesandlifestylemodificationscanbebeneficial,yourhealthcareprovidermaystillrecommendmedicationorsurgerytomanageGERDsymptoms.

Overall,aholisticapproachtomanagingGERDcanproducepositiveresultsandimprovequalityoflife.Bycombiningcomplementarytherapies,lifestylemodifications,andmedicalinterventionsasneeded,patientscantakecontroloftheirhealthandimprovetheirlong-termoutcomes。Inadditiontotheaforementionedstrategies,thereareanumberofothertechniquesandinterventionsthatindividualswithGERDcanconsider.Forexample,acupuncture,atraditionalChinesemedicinepractice,hasbeenfoundtobeeffectiveintreatingGERDsymptomssuchasheartburnandacidreflux.Byinsertingthinneedlesintospecificpointsonthebody,acupuncturecanhelptoregulatethebody'senergyflowandalleviatedigestiveissues.ThismethodhasbeenshowntobeeffectiveinreducingthefrequencyandseverityofGERDsymptomsandimprovingqualityoflifeforsomepatients.

AnothercomplementarytherapythatmaybeusefulforGERDismassagetherapy.Byapplyingpressureandmanipulatingthemusclesintheabdomenandchestarea,massagetherapycanhelptorelaxthemusclesthatcontroltheesophagealsphincter,therebyreducingthelikelihoodofacidreflux.Massagetherapyhasalsobeenfoundtobeaneffectivestress-reductiontechnique,whichcanhelptoalleviatesomeoftheunderlyingcausesofGERD.

Inadditiontocomplementarytherapies,thereareanumberoflifestylemodificationsthatcanbemadetoalleviateGERDsymptoms.Forexample,dietarychangessuchasavoidingtriggerfoods(e.g.spicyoracidicfoods),eatingsmallerandmorefrequentmeals,andavoidingeatingclosetobedtimemayallbebeneficial.MaintainingahealthyweightandavoidingsmokingandalcoholmayalsohelptoreduceGERDsymptoms.

Finally,iflifestylemodificationsandcomplementarytherapiesarenotsufficienttomanageGERDsymptoms,medicalinterventionssuchasmedicationorsurgerymaybenecessary.Protonpumpinhibitors(PPIs)andH2blockersarecommonlyprescribedmedicationsthatcanhelptoreduceacidproductionandalleviateGERDsymptoms.Surgery,suchasfundoplication,mayberecommendedinseverecaseswhereothertreatmentshavenotbeeneffective.

Inconclusion,GERDisacommonconditionthatcansignificantlyimpactqualityoflife.However,bytakingaholisticapproachtomanagingGERDthatincorporatescomplementarytherapies,lifestylemodifications,andmedicalinterventionsasneeded,individualscaneffectivelyalleviatesymptomsandimprovetheirlong-termoutcomes.Itisimportanttoworkcloselywithhealthcareprovidersand/orTCMpractitionerstodevelopanindividualizedtreatmentplanthataddressesspecificneedsandpreferences。OneofthekeycomponentsofmanagingGERDismakinglifestylemodifications.Thisincludesavoidingtriggerssuchasfattyorspicyfoods,alcohol,tobacco,andcaffeine.Itisalsoimportanttomaintainahealthyweight,exerciseregularly,andeatsmaller,morefrequentmealsthroughouttheday.Elevatingtheheadofthebedwhilesleepingcanalsohelpalleviatesymptoms.

ComplementarytherapiescanalsobehelpfulinmanagingGERD.Acupuncture,forexample,hasbeenshowntobeeffectiveinreducingsymptomssuchasheartburnandregurgitation.Herbalremediessuchaslicoricerootandslipperyelmmayalsohelpsoothethedigestivesystemandreduceinflammation.

Inadditiontolifestylemodificationsandcomplementarytherapies,medicalinterventionsmaybenecessaryinsomecases.Medicationssuchasantacids,H2blockers,andprotonpumpinhibitorscanhelpreducetheproductionof