皮膚性病接觸性皮炎英文教學(xué)課件

1、Contact Dermatitis接觸性皮炎Definition1Etiology and pathogenesis2Clinical manifestations3Diagnosis and differential diagnosis4Treatment 5 DefinitionContact dermatitis indicates that people get in touch with some substances leads to acute or chronic inflammation on the skin or/and mucosa (粘膜).Etiology and

2、 pathogenesisIrritant contact dermatitis 80%mechanismAllergic contact dermatitis20%Irritant contact dermatitisSome substances are allergic materials on low concentration, but they can be irritant or toxic substances when the concentration is high Substances themselves are irritant or toxicCharacters

3、: The eruptions can occur on everybody who get in touch with them No incubation period(潛伏期) Only place on contact area, boundary is clear Self-limited when remove the allergenEtiology and pathogenesisIrritant contact dermatitis 80%mechanismAllergic contact dermatitis20%Allergic contact dermatitisAll

4、ergic contact dermatitis indicates an acquired sensitivity to various substances that produce inflammatory reactions in those, and only those who have been exposed to the allergen. Allergic reaction type , delayed allergyOnly a few people will be attacked who contact the allergen Characters: Incubat

5、ion period(潛伏期) Place symmetrically(對(duì)稱) Easy to recur Patch test (+) Clinic manifestationAcute stageSubacute stageChronic stageCDAcute contact dermatitis Occur quickly Erythema(紅斑), papule(丘疹), papulovesicle(丘皰 疹) can be seen on contact place, vesicles(小水皰) and bulla(大皰) in severe cases, erosion and

6、 necrosis Boundary is clear Place only on contact area Contacting pattern determines the shape of lesions Itch or painNitric acidAlkaliErythema(紅斑), papule(丘疹), mild proliferation and lichenification(苔蘚樣變)Subacute and chronic contact dermatitisDiaper dermatitis Special contact dermatitisDDNH3diaperb

7、acteriaDiaper dermatitis The diaper replacing is delayed Bacteria Ammonia(氨) Placed on pudendum(陰部), perineum(會(huì)陰) and buttock(臀部), sometimes it spreads to groin(腹股溝) Erythema(紅斑), maculopapule(斑丘疹), papule(丘疹), pustule(膿皰), erosion and ulcers Edge is clearDiaper dermatitisDermatitis rhusDirect touch

8、 or indirect contactAcute clinical featuresPlaced on exposed areas, erythema(紅斑), edema(水腫), papule(丘疹), papulovesticle(丘皰疹) and vesicle(小水皰), bulla(大皰)The cause of allergic contact dermatitis is from fragrance and hair dyeIt can be acute, subacute and chronicLesions can be limited or being spread t

9、o whole bodyCosmetic dermatitisHistory-contact allergenLesions place on contact areaBoundary is clearSelf-limitedPatch test (+)Diagnosis and differential diagnosisPatch testFind causes, avoidance of the primary causeAntihistamine drugs(抗組胺藥) are necessaryAcute stage, calamine lotion(爐甘石洗劑), 3% boric acid(硼酸) wet compress; in subacute, oil of zinc oxide(氧化鋅); in chronic, ointm