TCS-359 - FLT3 抑制劑 - 生命科學(xué)試劑 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETCS 359Cat. No.: HY-13907CAS No.: 301305-73-7分式: CHNOS分量: 360.43作靶點(diǎn): FLT3作通路: Protein Tyrosine Kinase/RTK儲存式: 4C, protect from light* In solvent : -80C, 6 months; -20C, 1 month (protect fromlight)溶解性數(shù)據(jù)體外實(shí)驗(yàn) DMSO : 14.29 mg/mL (39

2、.65 mM; Need ultrasonic)Mass Solvent1 mg 5 mg 10 mg Concentration制備儲備液1 mM 2.7745 mL 13.8723 mL 27.7446 mL5 mM 0.5549 mL 2.7745 mL 5.5489 mL10 mM 0.2774 mL 1.3872 mL 2.7745 mL請根據(jù)產(chǎn)品在不同溶劑中的溶解度，選擇合適的溶劑配制儲備液，并請注意儲備液的保存式和期限。體內(nèi)實(shí)驗(yàn) 請根據(jù)您的實(shí)驗(yàn)動物和給藥式選擇適當(dāng)?shù)娜芙獍福渲魄罢埾扰渲瞥吻宓膬湟?，再依次添加助溶?為保證實(shí)驗(yàn)結(jié)果的可靠性，體內(nèi)實(shí)驗(yàn)的作液，建議您現(xiàn)現(xiàn)配，當(dāng)天使；

3、澄清的儲備液可以根據(jù)儲存條件，適當(dāng)保存；以下溶劑前的百分 指該溶劑在您配制終溶液中的體積占)：1. 請依序添加每種溶劑： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 1.43 mg/mL (3.97 mM); Suspended solution; Need ultrasonic2. 請依序添加每種溶劑： 10% DMSO 90% corn oilSolubility: 1.43 mg/mL (3.97 mM); Clear solutionBIOLOGICAL ACTIVITY1/2 Master of Small Molecu

4、les 您邊的抑制劑師www.MedChemE物活性 TCS 359是FLT3抑制劑，IC50為42 nM。戶使本產(chǎn)品發(fā)表的科研獻(xiàn) Oncotarget. 2016 May 17;7(20):29131-42.See more customer validations on HYPERLINK / www.MedChemEREFERENCES1. Patch RJ, et al. Identification of 2-acylaminothiophene-3-carboxamides as potent inhibitors of FLT3. Bioorg Med Chem Lett. 2006 Jun15;16(12):3282-6.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: